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Neuroscientists today can measure activity from more neurons than ever before, and are facing the challenge of connecting these brain-wide neural recordings to computation and behavior. Here, we first describe emerging tools and…

Neurons and Cognition · Quantitative Biology 2022-01-10 Anne E. Urai , Brent Doiron , Andrew M. Leifer , Anne K. Churchland

Two major initiatives to accelerate research in the brain sciences have focused attention on developing a new generation of scientific instruments for neuroscience. These instruments will be used to record static (structural) and dynamic…

Neurons and Cognition · Quantitative Biology 2013-07-30 Thomas Dean , Biafra Ahanonu , Mainak Chowdhury , Anjali Datta , Andre Esteva , Daniel Eth , Nobie Redmon , Oleg Rumyantsev , Ysis Tarter

A statistical framework is introduced for a broad class of problems involving synchronization or registration of data across a sensor network in the presence of noise. This framework enables an estimation-theoretic approach to the design…

Networking and Internet Architecture · Computer Science 2010-10-15 Stephen D. Howard , Douglas Cochran , William Moran , Frederick R. Cohen

Models of neural networks have proven their utility in the development of learning algorithms in computer science and in the theoretical study of brain dynamics in computational neuroscience. We propose in this paper a spatial neural…

Neural and Evolutionary Computing · Computer Science 2014-05-06 Lucas Antiqueira , Liang Zhao

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

Neurons and Cognition · Quantitative Biology 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

Many questions in neuroscience involve understanding of the responses of large populations of neurons. However, when dealing with large-scale neural activity, interpretation becomes difficult, and comparisons between two animals, or across…

Neurons and Cognition · Quantitative Biology 2022-05-18 Max Dabagia , Konrad P Kording , Eva L Dyer

Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely new approaches may be required, motivating an analysis…

Neuroscientists classify neurons into different types that perform similar computations at different locations in the visual field. Traditional methods for neural system identification do not capitalize on this separation of 'what' and…

Machine Learning · Statistics 2018-01-30 David A. Klindt , Alexander S. Ecker , Thomas Euler , Matthias Bethge

In distributed-parameter inverse problems in computational mechanics, spatially varying fields are inferred from noisy, indirect, and heterogeneous observations. The relevant identifiability question concerns which spatial perturbation…

Computational Engineering, Finance, and Science · Computer Science 2026-05-28 Tammam Bakeer

Spike train signals recorded from a large population of neurons often exhibit low-dimensional spatio-temporal structure and modeled as conditional Poisson observations. The low-dimensional signals that capture internal brain states are…

Neurons and Cognition · Quantitative Biology 2024-08-19 Hyungju Jeon , Il Memming Park

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Considering visual localization accuracy at the planning time gives preference to robot motion that can be better localized and thus has the potential of improving vision-based navigation, especially in visually degraded environments. To…

Robotics · Computer Science 2020-08-11 Zichao Zhang , Davide Scaramuzza

We consider the information transmission problem in neurons and its possible implications for learning in neural networks. Our approach is based on recent developments in statistical physics and complexity science. Combining sensory…

Neurons and Cognition · Quantitative Biology 2025-09-30 Siddharth Kackar

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

Neural signals are characterized by rich temporal and spatiotemporal dynamics that reflect the organization of cortical networks. Theoretical research has shown how neural networks can operate at different dynamic ranges that correspond to…

Neurons and Cognition · Quantitative Biology 2017-07-05 Luca Ambrogioni , Marcel A. J. van Gerven , Eric Maris

We consider the task of region-based source separation of reverberant multi-microphone recordings. We assume pre-defined spatial regions with a single active source per region. The objective is to estimate the signals from the individual…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-14 Julian Wechsler , Srikanth Raj Chetupalli , Wolfgang Mack , Emanuël A. P. Habets

Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…

Neurons and Cognition · Quantitative Biology 2024-03-25 Rubén Calvo , Carles Martorell , Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Multi-electrode arrays (MEAs) can record extracellular action potentials (also known as 'spikes') from hundreds or thousands of neurons simultaneously. Inference of a functional network from a spike train is a fundamental and formidable…

Computational Engineering, Finance, and Science · Computer Science 2020-07-07 Yun Zhao , Richard Jiang , Zhenni Xu , Elmer Guzman , Paul K. Hansma , Linda Petzold

A central goal of neuroscience is to understand the representations formed by brain activity patterns and their connection to behavior. The classical approach is to investigate how individual neurons encode the stimuli and how their tuning…

Neurons and Cognition · Quantitative Biology 2021-04-21 Nikolaus Kriegeskorte , Xue-Xin Wei

Neural networks are known to exploit spurious artifacts (or shortcuts) that co-occur with a target label, exhibiting heuristic memorization. On the other hand, networks have been shown to memorize training examples, resulting in…

Machine Learning · Computer Science 2024-02-05 Rachit Bansal , Danish Pruthi , Yonatan Belinkov
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