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The identification of cells and particles based on their transport properties in microfluidic devices is crucial for numerous applications in biology and medicine. Neutrally buoyant particles transported in microfluidic channels, migrate…

A flowing pair of particles in inertial microfluidics gives important insights into understanding and controlling the collective dynamics of particles like cells or droplets in microfluidic devices. They are applied in medical cell analysis…

Fluid Dynamics · Physics 2018-05-25 Christian Schaaf , Felix Rühle , Holger Stark

Inertial microfluidic is able to focus and separate particles in microchannels based on the characteristic geometry and intrinsic hydrodynamic effect. Yet, the vertical position of suspended particles in the microchannel cannot be…

Fluid Dynamics · Physics 2022-07-22 Chengliang Xuan , Weiyin Liang , Bing He , Binghai Wen

Inertial microfluidics is a promising tool for many lab-on-a-chip applications. Particles in channel flows with Reynolds numbers above one undergo cross-streamline migration to a discrete set of equilibrium positions in square and…

Fluid Dynamics · Physics 2014-02-04 Christopher Prohm , Holger Stark

In recent years, manipulation of particles by inertial microfluidics has attracted significant attention. Most studies focused on inertial focusing of particles suspended within liquid phase, in which the ratio of the density of the…

Fluid Dynamics · Physics 2018-12-07 Maoqiang Jiang , Shizhi Qian , Zhaohui Liu

At finite Reynolds numbers, Re, particles migrate across laminar flow streamlines to their equilibrium positions in microchannels. This migration is attributed to a lift force, and the balance between this lift and gravity determines the…

Inertial lift forces are exploited within inertial microfluidic devices to position, segregate, and sort particles or droplets. However the forces and their focusing positions can currently only be predicted by numerical simulations, making…

Fluid Dynamics · Physics 2016-07-21 Kaitlyn Hood , Sungyon Lee , Marcus Roper

At finite Reynolds numbers particles migrate across flow streamlines to their equilibrium positions in microchannels. Such a migration is attributed to an inertial lift force, and it is well-known that the equilibrium location of…

Soft Condensed Matter · Physics 2020-01-17 Tatiana V. Nizkaya , Evgeny S. Asmolov , Jens Harting , Olga I. Vinogradova

Particles suspended in a fluid flow through a curved duct can focus to specific locations within the duct cross-section. This particle focusing is a result of a balance between two dominant forces acting on the particle: (i) the inertial…

Dynamical Systems · Mathematics 2024-01-17 Rahil N. Valani , Brendan Harding , Yvonne M. Stokes

Particles traveling at high velocities through microfluidic channels migrate from their starting streamlines due to inertial lift forces. Theories predict different scaling laws for these forces and there is little experimental evidence by…

Fluid Dynamics · Physics 2017-07-06 Kaitlyn Hood , Soroush Kahkeshani , Dino Di Carlo , Marcus Roper

Particles suspended in fluid flow through a curved duct focus to stable equilibrium positions in the duct cross-section due to the balance of two dominant forces: (i) inertial lift force - arising from the inertia of the fluid, and (ii)…

Fluid Dynamics · Physics 2021-12-10 Rahil N. Valani , Brendan Harding , Yvonne M. Stokes

This study investigates the lift force acting on a finite-size, neutrally buoyant spherical particle suspended in a liquid while flowing through a shallow channel at low Reynolds numbers. Using an immersed boundary method, we calculate the…

Fluid Dynamics · Physics 2026-04-29 Guiquan Wang , Willem Van Roy , Chengxun Liu , Tim Stakenborg , Benjamin Jones

This study examines the motion of spherical inertial particles in a three-dimensional rotating cylindrical vortex - a simplified model of geophysical flow structures such as oceanic eddies. The analytical vortex formulation enables the…

Fluid Dynamics · Physics 2025-06-12 Orr Avni , Alok Kumar , Yuval Dagan

Particles suspended in fluid flow through a closed duct can focus to specific stable locations in the duct cross-section due to hydrodynamic forces arising from the inertia of the disturbed fluid. Such particle focusing is exploited in…

Fluid Dynamics · Physics 2023-01-25 Rahil Valani , Brendan Harding , Yvonne Stokes

KEY WORDS suspensions, inertial focusing, particle-laden flows, high Reynolds numbers SHORT SUMMARY The inertial migration of particles in square channel flows at the micro-scale has been deeply investigated in the last two decades. The…

Soft Condensed Matter · Physics 2019-03-20 Yichang Wang , Yanfeng Gao , Pascale Magaud , Lucien Baldas , Christine Lafforgue , Stéphane Colin

The mechanical deformability of single cells is an important indicator for various diseases such as cancer, blood diseases and inflammation. Lab-on-a-chip devices allow to separate such cells from healthy cells using hydrodynamic forces. We…

Fluid Dynamics · Physics 2019-02-08 Christian Schaaf , Holger Stark

In inertial microfluidics colloidal particles in a Poiseuille flow experience the Segr\'e-Silberberg lift force, which drives them to specific positions in the channel cross section. Due to the Saffman effect an external force applied along…

Soft Condensed Matter · Physics 2020-06-15 Felix Rühle , Christian Schaaf , Holger Stark

In microfluidic devices, inertia drives particles to focus on a finite number of inertial focusing streamlines. Particles on the same streamline interact to form one-dimensional microfluidic crystals (or "particle trains"). Here we develop…

Fluid Dynamics · Physics 2018-09-12 Kaitlyn Hood , Marcus Roper

We observe novel positional control of a colloidal particle in microchannel flow of a nematic liquid crystal. Lattice Boltzmann simulations show multiple equilibrium particle positions, the existence and position of which are tunable using…

Soft Condensed Matter · Physics 2022-09-26 Magdalena Lesniewska , Nigel Mottram , Oliver Henrich

Inertial focusing in curved microfluidic ducts exploits the interaction of drag force from the Dean flow with the inertial lift force to separate particles or cells laterally across the cross-section width according to their size.…

Fluid Dynamics · Physics 2023-10-31 Brendan Harding , Yvonne M. Stokes , Rahil N. Valani
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