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Self-supervised representation learning on image-text data facilitates crucial medical applications, such as image classification, visual grounding, and cross-modal retrieval. One common approach involves contrasting semantically similar…

Machine Learning · Computer Science 2023-08-15 Peiqi Wang , Yingcheng Liu , Ching-Yun Ko , William M. Wells , Seth Berkowitz , Steven Horng , Polina Golland

The performance of machine learning models is determined by the quality of their learned features. They should be invariant under irrelevant data variation but sensitive to task-relevant details. To visualize whether this is the case, we…

Machine Learning · Computer Science 2026-03-24 Armand Rousselot , Joran Wendebourg , Ullrich Köthe

We consider the problem of image representation for the tasks of unsupervised learning and semi-supervised learning. In those learning tasks, the raw image vectors may not provide enough representation for their intrinsic structures due to…

Machine Learning · Computer Science 2014-02-20 Yiyi Liao , Yue Wang , Yong Liu

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

This paper introduces a novel approach to leverage features learned from both supervised and self-supervised paradigms, to improve image classification tasks, specifically for vehicle classification. Two state-of-the-art self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Shihan Ma , Jidong J. Yang

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

An important topic in medical research is the process of improving the images obtained from medical devices. As a consequence, there is also a need to improve medical image resolution and analysis. Another issue in this field is the large…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Elena-Simona Apostol , Ciprian-Octavian Truică

Previous work has shown that feature maps of deep convolutional neural networks (CNNs) can be interpreted as feature representation of a particular image region. Features aggregated from these feature maps have been exploited for image…

Computer Vision and Pattern Recognition · Computer Science 2016-11-08 Jiedong Hao , Jing Dong , Wei Wang , Tieniu Tan

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Intensity inhomogeneities in images constitute a considerable challenge in image segmentation. In this paper we propose a novel biconvex variational model to tackle this task. We combine a total variation approach for multi class…

Numerical Analysis · Mathematics 2017-05-09 Jan Henrik Fitschen , Katharina Losch , Gabriele Steidl

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

Tissues and Organs · Quantitative Biology 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Medical Image Retrieval is a challenging field in Visual information retrieval, due to the multi-dimensional and multi-modal context of the underlying content. Traditional models often fail to take the intrinsic characteristics of data into…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Sowmya Kamath S , Karthik K

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Proximity Distribution Kernel is an effective method for bag-of-featues based image representation. In this paper, we investigate the soft assignment of visual words to image features for proximity distribution. Visual word contribution…

Computer Vision and Pattern Recognition · Computer Science 2014-06-03 Quanquan Wang , Yongping Li

Few-shot classification aims to learn to classify new object categories well using only a few labeled examples. Transferring feature representations from other models is a popular approach for solving few-shot classification problems. In…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Chun-Nam Yu , Yi Xie

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…