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Loss of plasticity is one of the main challenges in continual learning with deep neural networks, where neural networks trained via backpropagation gradually lose their ability to adapt to new tasks and perform significantly worse than…

Machine Learning · Computer Science 2025-03-27 Jiuqi Wang , Rohan Chandra , Shangtong Zhang

One aim shared by multiple settings, such as continual learning or transfer learning, is to leverage previously acquired knowledge to converge faster on the current task. Usually this is done through fine-tuning, where an implicit…

Machine Learning · Computer Science 2023-10-17 Tudor Berariu , Wojciech Czarnecki , Soham De , Jorg Bornschein , Samuel Smith , Razvan Pascanu , Claudia Clopath

Neuronal circuits can learn and replay firing patterns evoked by sequences of sensory stimuli. After training, a brief cue can trigger a spatiotemporal pattern of neural activity similar to that evoked by a learned stimulus sequence.…

Neurons and Cognition · Quantitative Biology 2015-07-03 Alan Veliz-Cuba , Harel Shouval , Kresimir Josic , Zachary P. Kilpatrick

This paper introduces an algorithm for discovering implicit and delayed causal relations between events observed by a robot at arbitrary times, with the objective of improving data-efficiency and interpretability of model-based…

Machine Learning · Computer Science 2020-08-05 Junchi Liang , Abdeslam Boularias

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

Learning, especially rapid learning, is critical for survival. However, learning is hard: a large number of synaptic weights must be set based on noisy, often ambiguous, sensory information. In such a high-noise regime, keeping track of…

Neurons and Cognition · Quantitative Biology 2021-03-22 Laurence Aitchison , Jannes Jegminat , Jorge Aurelio Menendez , Jean-Pascal Pfister , Alex Pouget , Peter E. Latham

Large language models display in-context learning as an emergent effect of scale, but they rely on static weights during inference. In contrast, biological systems continually adapt via synaptic plasticity. We investigate whether explicit,…

Neural and Evolutionary Computing · Computer Science 2025-11-06 Siddharth Chaudhary

Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

Neurons and Cognition · Quantitative Biology 2026-05-20 Genki Shimizu , Taro Toyoizumi

Deep continual learning requires models to adapt to new tasks without retraining from scratch. However, neural networks can lose their ability to adapt to new tasks after training on previous ones, a phenomenon known as loss of plasticity.…

Machine Learning · Computer Science 2026-05-12 Jiuqi Wang , Jayanth Srinivasa , Claire Chen , Shuze Daniel Liu , Ali Payani , Shangtong Zhang

Real-world deployment of machine learning models is challenging because data evolves over time. While no model can work when data evolves in an arbitrary fashion, if there is some pattern to these changes, we might be able to design methods…

Machine Learning · Computer Science 2024-05-03 Rasool Fakoor , Jonas Mueller , Zachary C. Lipton , Pratik Chaudhari , Alexander J. Smola

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

Time-dependent data-generating distributions have proven to be difficult for gradient-based training of neural networks, as the greedy updates result in catastrophic forgetting of previously learned knowledge. Despite the progress in the…

Machine Learning · Computer Science 2023-04-03 Matthias De Lange , Gido van de Ven , Tinne Tuytelaars

Recent alignment techniques, such as reinforcement learning from human feedback, have been widely adopted to align large language models with human preferences by learning and leveraging reward models. In practice, these models often…

Machine Learning · Computer Science 2025-10-29 Ignavier Ng , Patrick Blöbaum , Siddharth Bhandari , Kun Zhang , Shiva Kasiviswanathan

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

Neural and Evolutionary Computing · Computer Science 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

Rewards play an essential role in reinforcement learning. In contrast to rule-based game environments with well-defined reward functions, complex real-world robotic applications, such as contact-rich manipulation, lack explicit and…

Machine Learning · Computer Science 2022-05-30 Yuning Wu , Jieliang Luo , Hui Li

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

Neural and Evolutionary Computing · Computer Science 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

To learn useful dynamics on long time scales, neurons must use plasticity rules that account for long-term, circuit-wide effects of synaptic changes. In other words, neural circuits must solve a credit assignment problem to appropriately…

Neurons and Cognition · Quantitative Biology 2019-05-30 Owen Marschall , Kyunghyun Cho , Cristina Savin

Continual learning is inherently a constrained learning problem. The goal is to learn a predictor under a no-forgetting requirement. Although several prior studies formulate it as such, they do not solve the constrained problem explicitly.…

Machine Learning · Computer Science 2024-06-03 Juan Elenter , Navid NaderiAlizadeh , Tara Javidi , Alejandro Ribeiro

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

Neurons and Cognition · Quantitative Biology 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

Causal models bring many benefits to decision-making systems (or agents) by making them interpretable, sample-efficient, and robust to changes in the input distribution. However, spurious correlations can lead to wrong causal models and…

Machine Learning · Computer Science 2020-12-09 Sergei Volodin , Nevan Wichers , Jeremy Nixon
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