English
Related papers

Related papers: Alignment-free comparison of next-generation seque…

200 papers

In Bora et al. (2017), a mathematical framework was developed for compressed sensing guarantees in the setting where the measurement matrix is Gaussian and the signal structure is the range of a generative neural network (GNN). The problem…

Information Theory · Computer Science 2022-11-10 Aaron Berk , Simone Brugiapaglia , Babhru Joshi , Yaniv Plan , Matthew Scott , Özgür Yilmaz

In this paper, we study the problem of compressed sensing using binary measurement matrices and $\ell_1$-norm minimization (basis pursuit) as the recovery algorithm. We derive new upper and lower bounds on the number of measurements to…

Machine Learning · Statistics 2020-04-28 Mahsa Lotfi , Mathukumalli Vidyasagar

The recent development of artificial intelligence (AI) technology, especially the advance of deep neural network (DNN) technology, has revolutionized many fields. While DNN plays a central role in modern AI technology, it has been rarely…

Machine Learning · Statistics 2023-12-07 Tingting Hou , Chang Jiang , Qing Lu

Associating genetic markers with a multidimensional phenotype is an important yet challenging problem. In this work, we establish the equivalence between two popular methods: kernel-machine regression (KMR), and kernel distance covariance…

Machine Learning · Statistics 2014-04-03 Wen-Yu Hua , Debashis Ghosh

Gromov-Wasserstein (GW) is a powerful tool to compare probability measures whose supports are in different metric spaces. GW suffers however from a computational drawback since it requires to solve a complex non-convex quadratic program. We…

Machine Learning · Statistics 2020-06-18 Tam Le , Nhat Ho , Makoto Yamada

Likelihood-free methods are useful for parameter estimation of complex models with intractable likelihood functions for which it is easy to simulate data. Such models are prevalent in many disciplines including genetics, biology, ecology…

Methodology · Statistics 2022-03-29 Christopher Drovandi , David T Frazier

The excellent performance of deep neural networks is usually accompanied by a large number of parameters and computations, which have limited their usage on the resource-limited edge devices. To address this issue, abundant methods such as…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Muzhou Yu , Linfeng Zhang , Kaisheng Ma

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

We survey permutation-based methods for approximate k-nearest neighbor search. In these methods, every data point is represented by a ranked list of pivots sorted by the distance to this point. Such ranked lists are called permutations. The…

Machine Learning · Computer Science 2016-11-01 Bilegsaikhan Naidan , Leonid Boytsov , Eric Nyberg

Edit distances between merge trees of scalar fields have many applications in scientific visualization, such as ensemble analysis, feature tracking or symmetry detection. In this paper, we propose branch mappings, a novel approach to the…

Computational Geometry · Computer Science 2022-08-12 Florian Wetzels , Heike Leitte , Christoph Garth

Finite-context models (FCMs) are widely used for compressing symbolic sequences such as DNA, where predictive performance depends critically on the context length k and smoothing parameter {\alpha}. In practice, these hyperparameters are…

Machine Learning · Statistics 2026-03-23 José Contente , Ana Martins , Armando J. Pinho , Sónia Gouveia

We propose a metric for the space of multiple sequence alignments that can be used to compare two alignments to each other. In the case where one of the alignments is a reference alignment, the resulting accuracy measure improves upon…

Quantitative Methods · Quantitative Biology 2011-11-09 Ariel S. Schwartz , Eugene W. Myers , Lior Pachter

We have developed an alignment-free method that calculates phylogenetic distances using a maximum likelihood approach for a model of sequence change on patterns that are discovered in unaligned sequences. To evaluate the phylogenetic…

Quantitative Methods · Quantitative Biology 2007-05-23 Michael Höhl , Isidore Rigoutsos , Mark A. Ragan

Many commonly studied species now have more than one chromosome-scale genome assembly, revealing a large amount of genetic diversity previously missed by approaches that map short reads to a single reference. However, many species still…

Populations and Evolution · Quantitative Biology 2024-09-19 Miles D. Roberts , Olivia Davis , Emily B. Josephs , Robert J. Williamson

Second-generation sequencing technologies have replaced array-based technologies and become the default method for genomics and epigenomics analysis. Second-generation sequencing technologies sequence tens of millions of DNA/cDNA fragments…

Methodology · Statistics 2017-02-08 Ping Ma , Nan Zhang , Jianhua Z. Huang , Wenxuan Zhong

Smart Grids measure energy usage in real-time and tailor supply and delivery accordingly, in order to improve power transmission and distribution. For the grids to operate effectively, it is critical to collect readings from…

Information Theory · Computer Science 2012-02-24 Sheng Cai , Jihang Ye , Minghua Chen , Jianxin Yan , Sidharth Jaggi

In recent years, compressed sensing (CS) has been applied in the field of synthetic aperture radar (SAR) imaging and shows great potential. The existing models are, however, based on application of the sensing matrix acquired by the exact…

Information Theory · Computer Science 2014-05-23 Jian Fang , Zongben Xu , Bingchen Zhang , Wen Hong , Yirong Wu

Next-generation sequencing (NGS) is a pivotal technique in genome sequencing due to its high throughput, rapid results, cost-effectiveness, and enhanced accuracy. Its significance extends across various domains, playing a crucial role in…

Genomics · Quantitative Biology 2025-04-28 Fathima Nuzla Ismail , Shanika Amarasoma

Kernel methods are powerful tools in machine learning. They have to be computationally efficient. In this paper, we present a novel Geometric-based approach to compute efficiently the string subsequence kernel (SSK). Our main idea is that…

Machine Learning · Computer Science 2015-03-02 Slimane Bellaouar , Hadda Cherroun , Djelloul Ziadi

The edit distance under the DCJ model can be computed in linear time for genomes with equal content or with Indels. But it becomes NP-Hard in the presence of duplications, a problem largely unsolved especially when Indels are considered. In…

Data Structures and Algorithms · Computer Science 2017-05-29 Zhaoming Yin , Jijun Tang , Stephen W. Schaeffer , David A. Bader