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Next-generation sequencing (NGS) is a pivotal technique in genome sequencing due to its high throughput, rapid results, cost-effectiveness, and enhanced accuracy. Its significance extends across various domains, playing a crucial role in…

Genomics · Quantitative Biology 2025-04-28 Fathima Nuzla Ismail , Shanika Amarasoma

Optical Music Recognition (OMR) is an important technology within Music Information Retrieval. Deep learning models show promising results on OMR tasks, but symbol-level annotated data sets of sufficient size to train such models are not…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Eelco van der Wel , Karen Ullrich

Objective: To develop and evaluate a scalable methodology for harmonizing inconsistent units in large-scale clinical datasets, addressing a key barrier to data interoperability. Materials and Methods: We designed a novel unit harmonization…

Machine Learning · Computer Science 2025-11-18 Jordi de la Torre

Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

Hardware Architecture · Computer Science 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

Data diversity and volume are crucial to the success of training deep learning models, while in the medical imaging field, the difficulty and cost of data collection and annotation are especially huge. Specifically in robotic surgery, data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-08 An Wang , Mobarakol Islam , Mengya Xu , Hongliang Ren

Deep learning is one of the most successful and far-reaching strategies used in machine learning today. However, the scale and utility of neural networks is still greatly limited by the current hardware used to train them. These concerns…

Machine Learning · Computer Science 2022-01-12 Davis Arthur , Prasanna Date

Automatic Music Generation (AMG) has become an interesting research topic for many scientists in artificial intelligence, who are also interested in the music industry. One of the main challenges in AMG is that there is no clear objective…

Artificial Intelligence · Computer Science 2022-06-06 Maryam Majidi , Rahil Mahdian Toroghi

Scientific research increasingly depends on robust and scalable IT infrastructures to support complex computational workflows. With the proliferation of services provided by research infrastructures, NRENs, and commercial cloud providers,…

Kernel methods are an important class of techniques in machine learning. To be effective, good feature maps are crucial for mapping non-linearly separable input data into a higher dimensional (feature) space, thus allowing the data to be…

Quantum Physics · Physics 2024-07-16 Rowan Pellow-Jarman , Anban Pillay , Ilya Sinayskiy , Francesco Petruccione

The growing availability of observational databases like electronic health records (EHR) provides unprecedented opportunities for secondary use of such data in biomedical research. However, these data can be error-prone and need to be…

Methodology · Statistics 2024-05-28 Sarah C. Lotspeich , Gustavo G. C. Amorim , Pamela A. Shaw , Ran Tao , Bryan E. Shepherd

The two most common data-structures for genome indexing, FM-indices and hash-tables, exhibit a fundamental trade-off between memory footprint and performance. We present Ranger, a new indexing technique for nucleotide sequences that is both…

Data Structures and Algorithms · Computer Science 2023-08-09 Alon Rashelbach , Ori Rottensterich , Mark Silberstien

Large-scale genomic workflows used in precision medicine can process datasets spanning tens to hundreds of gigabytes per sample, leading to high memory spikes, intensive disk I/O, and task failures due to out-of-memory errors. Simple static…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Daniel Mas Montserrat , Ray Verma , Míriam Barrabés , Francisco M. de la Vega , Carlos D. Bustamante , Alexander G. Ioannidis

We propose HILBERT (HIerarchical Long-sequence Balanced Embedding with Reciprocal contrastive Training), a cross-attentive multimodal framework for learning document-level audio-text representations from long, segmented sequences in…

Machine Learning · Computer Science 2026-04-20 Habibeh Naderi , Behrouz Haji Soleimani , Stan Matwin

In systems biology, it is becoming increasingly common to measure biochemical entities at different levels of the same biological system. Hence, data fusion problems are abundant in the life sciences. With the availability of a multitude of…

Summary: Microbiome HiFi Amplicon Sequence Simulator (MHASS) creates realistic synthetic PacBio HiFi amplicon sequencing datasets for microbiome studies, by integrating genome-aware abundance modeling, realistic dual-barcoding strategies,…

Genomics · Quantitative Biology 2025-09-17 Rye Howard-Stone , Ion Mandoiu

The Burrows-Wheeler Transform (BWT) is a word transformation introduced in 1994 for Data Compression. It has become a fundamental tool for designing self-indexing data structures, with important applications in several area in science and…

Data Structures and Algorithms · Computer Science 2019-07-05 Raffaele Giancarlo , Giovanni Manzini , Antonio Restivo , Giovanna Rosone , Marinella Sciortino

High-Performance Computing (HPC) platforms enable scientific software to achieve breakthroughs in many research fields such as physics, biology, and chemistry, by employing Research Software Engineering (RSE) techniques. These include 1)…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-16 Matan Rusanovsky , Re'em Harel , Lee-or Alon , Idan Mosseri , Harel Levin , Gal Oren

This paper presents a new input format, channel-wise subband input (CWS), for convolutional neural networks (CNN) based music source separation (MSS) models in the frequency domain. We aim to address the major issues in CNN-based…

Audio and Speech Processing · Electrical Eng. & Systems 2023-10-10 Haohe Liu , Lei Xie , Jian Wu , Geng Yang

Mixed-precision neural network (MPNN) that utilizes just enough data width for the neural network processing is an effective approach to meet the stringent resources constraints including memory and computing of MCUs. Nevertheless, there is…

Hardware Architecture · Computer Science 2024-07-29 Junfeng Gong , Cheng Liu , Long Cheng , Huawei Li , Xiaowei Li

In this paper, we present a neural network approach for synchronizing audio recordings of human piano performances with their corresponding loosely aligned MIDI files. The task is addressed using a Convolutional Recurrent Neural Network…

Sound · Computer Science 2025-06-30 Sebastian Murgul , Moritz Reiser , Michael Heizmann , Christoph Seibert