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Modern machine learning algorithms are increasingly computationally demanding, requiring specialized hardware and distributed computation to achieve high performance in a reasonable time frame. Many hyperparameter search algorithms have…

Machine Learning · Computer Science 2018-07-16 Richard Liaw , Eric Liang , Robert Nishihara , Philipp Moritz , Joseph E. Gonzalez , Ion Stoica

Query-based universal sound separation is fundamental to intelligent auditory systems, aiming to isolate specific sources from mixtures. Despite recent advances, existing methods continue to suffer from residual interference in complex…

Sound · Computer Science 2026-02-02 Kai Li , Jintao Cheng , Chang Zeng , Zijun Yan , Helin Wang , Zixiong Su , Bo Zheng , Xiaolin Hu

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

The task of Multiple Sequence Alignment (MSA) is a constrained combinatorial optimization problem that is generally considered a complex computational problem. In this paper, we first present a binary encoding of MSA and devise a…

Highly-repetitive collections of strings are increasingly being amassed by genome sequencing and genetic variation experiments, as well as by storing all versions of human-generated files, like webpages and source code. Existing indexes for…

Data Structures and Algorithms · Computer Science 2016-04-22 Djamal Belazzougui , Fabio Cunial , Travis Gagie , Nicola Prezza , Mathieu Raffinot

Audio fingerprinting systems must efficiently and robustly identify query snippets in an extensive database. To this end, state-of-the-art systems use deep learning to generate compact audio fingerprints. These systems deploy indexing…

Audio and Speech Processing · Electrical Eng. & Systems 2023-01-20 Anup Singh , Kris Demuynck , Vipul Arora

A basic problem in metagenomics is to assign a sequenced read to the correct species in the reference collection. In typical applications in genomic epidemiology and viral metagenomics the reference collection consists of set of species…

Data Structures and Algorithms · Computer Science 2020-06-11 Dustin Cobas , Veli Mäkinen , Massimiliano Rossi

Efficient modeling of long sequences of high-order data requires a more efficient architecture than Transformer. In this paper, we investigate two key aspects of extending linear recurrent models, especially those originally designed for…

Machine Learning · Computer Science 2025-08-19 Yibo Zhong

DNA sequence alignment is an important workload in computational genomics. Reference-guided DNA assembly involves aligning many read sequences against candidate locations in a long reference genome. To reduce the computational load of this…

Hardware Architecture · Computer Science 2024-01-23 Courtney Golden , Dan Ilan , Nicholas Cebry , Christopher Batten

DNA sequencing to identify genetic variants is becoming increasingly valuable in clinical settings. Assessment of variants in such sequencing data is commonly implemented through Bayesian heuristic algorithms. Machine learning has shown…

Genomics is changing our understanding of humans, evolution, diseases, and medicines to name but a few. As sequencing technology is developed collecting DNA sequences takes less time thereby generating more genetic data every day. Today the…

Quantitative Methods · Quantitative Biology 2020-07-29 Sahand Salamat , Tajana Rosing

Sequence alignment is a memory bound computation whose performance in modern systems is limited by the memory bandwidth bottleneck. Processing-in-memory architectures alleviate this bottleneck by providing the memory with computing…

Hardware Architecture · Computer Science 2023-03-28 Safaa Diab , Amir Nassereldine , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu , Izzat El Hajj

Many applications of cross-modal music retrieval are related to connecting sheet music images to audio recordings. A typical and recent approach to this is to learn, via deep neural networks, a joint embedding space that correlates short…

Sound · Computer Science 2023-09-22 Luis Carvalho , Gerhard Widmer

Multiple signal classification algorithm (MUSICAL) provides a super-resolution microscopy method. In the previous research, MUSICAL has enabled data-parallelism well on a desktop computer or a Linux-based server. However, the running time…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Quan Do , Jon Ivar Kristiansen , Krishna Agarwal , Phuong Hoai Ha

In this paper we introduce a novel parallel pipeline for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, named HPG-Aligner, leverages the speed of the Burrows-Wheeler Transform to map…

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…

Large language models perform strongly on general tasks but remain constrained in specialized settings such as music, particularly in the music-entertainment domain, where corpus scale, purity, and the match between data and training…

Computation and Language · Computer Science 2025-11-19 Kai Tian , Yirong Mao , Wendong Bi , Hanjie Wang , Que Wenhui

In recent years, artificial neural networks (ANNs) have become a universal tool for tackling real-world problems. ANNs have also shown great success in music-related tasks including music summarization and classification, similarity…

Sound · Computer Science 2020-01-08 Stefan Lattner

Multivariate association analysis is of primary interest in many applications. Despite the prevalence of high-dimensional and non-Gaussian data (such as count-valued or binary), most existing methods only apply to low-dimensional data with…

Methodology · Statistics 2021-04-01 Gen Li , Irina Gaynanova

Motivation: The comparison of diverse genomic datasets is fundamental to understanding genome biology. Researchers must explore many large datasets of genome intervals (e.g., genes, sequence alignments) to place their experimental results…

Genomics · Quantitative Biology 2012-08-20 Ryan M. Layer , Kevin Skadron , Gabriel Robins , Ira M. Hall , Aaron R. Quinlan
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