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Molecular phenotypes link genomic information with organismic functions, fitness, and evolution. Quantitative traits are complex phenotypes that depend on multiple genomic loci. In this paper, we study the adaptive evolution of a…

Populations and Evolution · Quantitative Biology 2015-06-19 Torsten Held , Armita Nourmohammad , Michael Lässig

Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be the levels of signalling, movement and growth activity, etc.…

Cell Behavior · Quantitative Biology 2025-04-11 Tommaso Lorenzi , Kevin J Painter , Chiara Villa

Mating preferences of many biological species are not constant but season-dependent. Within the framework of evolutionary game theory this can be modeled with two finite opposite-sex populations playing against each other following the…

Populations and Evolution · Quantitative Biology 2015-08-13 Olena Tkachenko , Juzar Thingna , Sergey Denisov , Vasily Zaburdaev , Peter Hänggi

The phenotypic equilibrium, i.e. heterogeneous population of cancer cells tending to a fixed equilibrium of phenotypic proportions, has received much attention in cancer biology very recently. In previous literature, some theoretical models…

Cell Behavior · Quantitative Biology 2015-09-24 Yuanling Niu , Yue Wang , Da Zhou

We examine the feasibility of predicting and subsequently managing the future evolution of a Complex Adaptive System. Our archetypal system mimics a competitive population of mechanical, biological, informational or human objects. We show…

Disordered Systems and Neural Networks · Physics 2007-05-23 David M. D. Smith , Neil F. Johnson

Ecosystems frequently display the coexistence of diverse species under resource competition, typically resulting in skewed distributions of rarity and abundance. A potential driver of such coexistence is environmental fluctuations that…

Populations and Evolution · Quantitative Biology 2025-08-07 Davide Zanchetta , Deepak Gupta , Sofia Moschin , Samir Suweis , Amos Maritan , Sandro Azaele

A class of models for large-scale evolution and mass extinctions is presented. These models incorporate environmental changes on all scales, from influences on a single species to global effects. This is a step towards a unified picture of…

adap-org · Physics 2007-05-23 C. Wilke , S. Altmeyer , T. Martinetz

Frequency-dependent selection reflects the interaction between different species as they battle for limited resources in their environment. In a stochastic evolutionary game the species relative fitnesses guides the evolutionary dynamics…

Probability · Mathematics 2020-12-29 Lea Popovic , Liam Peuckert

Groups of animals often tend to arrange themselves in flocks that have characteristic spatial attributes and temporal dynamics. Using a dynamic continuum model for a flock of individuals, we find equilibria of finite spatial extent where…

Adaptation and Self-Organizing Systems · Physics 2012-01-16 Nicholas A. Mecholsky , Edward Ott , Thomas M. Antonsen , Parvez Guzdar

We study the Tangled Nature model of macro evolution and demonstrate that the co-evolutionary dynamics produces an increasingly correlated core of well occupied types. At the same time the entire configuration of types becomes increasing…

Statistical Mechanics · Physics 2015-03-13 Dominic Jones , Henrik Jeldtoft Jensen , Paolo Sibani

A simplified form of the time dependent evolutionary dynamics of a quasispecies model with a rugged fitness landscape is solved via a mapping onto a random flux model whose asymptotic behavior can be described in terms of a random walk. The…

Statistical Mechanics · Physics 2009-11-11 Clement Sire , Satya N. Majumdar , David S. Dean

We investigate steady states of a quasilinear first order hyperbolic partial integro-differential equation. The model describes the evolution of a hierarchical structured population with distributed states at birth. Hierarchical…

Analysis of PDEs · Mathematics 2019-03-25 J. Z. Farkas , P. Hinow

Ecosystems dynamics is often considered as driven by a coupling of species' resource consumption and its population size dynamics. Such resource-population dynamics is captured by MacArthur-type models. One biologically relevant feature…

Populations and Evolution · Quantitative Biology 2023-07-10 Elena Bellavere , Christian H. S. Hamster , Joshua A. Dijksman

To study population dynamics, ecologists and wildlife biologists use relative abundance data, which are often subject to temporal preferential sampling. Temporal preferential sampling occurs when sampling effort varies across time. To…

Methodology · Statistics 2022-12-14 Michael R. Schwob , Mevin B. Hooten , Travis McDevitt-Galles

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

Theoretical analysis proves that human survivability is dominated by an unusual physical, rather than biological, mechanism, which yields an exact law. The law agrees with all experimental data, but, contrary to existing theories, it is the…

Biological Physics · Physics 2009-11-07 Mark Ya. Azbel'

We study a system of PDEs modeling the population dynamics of two competitive species whose spatial movements are governed by both diffusion and mutually repulsive chemotaxis effects. We prove that solutions to this system are globally…

Analysis of PDEs · Mathematics 2022-02-16 Guanlin Li , Yao Yao

To explore the coupling between a growing population of microorganisms such as E. coli and a nonuniform nutrient distribution, we formulate a minimalistic model. It consists of active Brownian particles that divide and grow at a…

Biological Physics · Physics 2024-01-11 Till Welker , Holger Stark

Mathematical models play an increasingly important role in the interpretation of biological experiments. Studies often present a model that generates the observations, connecting hypothesized process to an observed pattern. Such generative…

Populations and Evolution · Quantitative Biology 2014-06-18 Steven A. Frank

We present an individual based model of evolutionary ecology. The reproduction rate of individuals characterized by their genome depends on the composition of the population in genotype space. Ecological features such as the taxonomy and…

Statistical Mechanics · Physics 2016-08-31 Matt Hall , Kim Christensen , Simone A. di Collobiano , Henrik Jeldtoft Jensen