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We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change…

Applications · Statistics 2012-04-10 Matt Silver , Eva Janousova , Xue Hua , Paul M. Thompson , Giovanni Montana

Incorporation of prior knowledge about organ shape and location is key to improve performance of image analysis approaches. In particular, priors can be useful in cases where images are corrupted and contain artefacts due to limitations in…

Canonical distances such as Euclidean distance often fail to capture the appropriate relationships between items, subsequently leading to subpar inference and prediction. Many algorithms have been proposed for automated learning of suitable…

Machine Learning · Statistics 2020-08-24 Tyler M. Tomita , Joshua T. Vogelstein

Traditionally, medical discoveries are made by observing associations and then designing experiments to test these hypotheses. However, observing and quantifying associations in images can be difficult because of the wide variety of…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Ryan Poplin , Avinash V. Varadarajan , Katy Blumer , Yun Liu , Michael V. McConnell , Greg S. Corrado , Lily Peng , Dale R. Webster

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

In recent years, ML algorithms have been shown to be useful for predicting diseases based on health data and posed a potential application area for these algorithms such as modeling of diseases. The majority of these applications employ…

Machine Learning · Computer Science 2024-12-24 Elham Musaaed , Nabil Hewahi , Abdulla Alasaadi

We describe the use of an unsupervised Random Forest for similarity learning and improved unsupervised anomaly detection. By training a Random Forest to discriminate between real data and synthetic data sampled from a uniform distribution…

Machine Learning · Statistics 2025-04-23 Joshua S. Harvey , Joshua Rosaler , Mingshu Li , Dhruv Desai , Dhagash Mehta

We propose a stochastic optimization method for minimizing loss functions, expressed as an expected value, that adaptively controls the batch size used in the computation of gradient approximations and the step size used to move along such…

Machine Learning · Computer Science 2020-03-04 Achraf Bahamou , Donald Goldfarb

Several computer vision and artificial intelligence projects are nowadays exploiting the manifold data distribution using, e.g., the diffusion process. This approach has produced dramatic improvements on the final performance thanks to the…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Federico Magliani , Laura Sani , Stefano Cagnoni , Andrea Prati

Machine learning is widely used in developing computer-aided diagnosis (CAD) schemes of medical images. However, CAD usually computes large number of image features from the targeted regions, which creates a challenge of how to identify a…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Morteza Heidari , Sivaramakrishnan Lakshmivarahan , Seyedehnafiseh Mirniaharikandehei , Gopichandh Danala , Sai Kiran R. Maryada , Hong Liu , Bin Zheng

Cardiovascular diseases are one of the most common causes of death in the world. Prevention, knowledge of previous cases in the family, and early detection is the best strategy to reduce this fact. Different machine learning approaches to…

Machine Learning · Computer Science 2019-10-07 Jefferson L. P. Lima , David Macêdo , Cleber Zanchettin

Detection of coronary artery stenosis in coronary CT angiography (CCTA) requires highly personalized surface meshes enclosing the coronary lumen. In this work, we propose to use graph convolutional networks (GCNs) to predict the spatial…

Image and Video Processing · Electrical Eng. & Systems 2019-08-16 Jelmer M. Wolterink , Tim Leiner , Ivana Išgum

We propose two deep neural network architectures for classification of arbitrary-length electrocardiogram (ECG) recordings and evaluate them on the atrial fibrillation (AF) classification data set provided by the PhysioNet/CinC Challenge…

Machine Learning · Computer Science 2018-04-10 Martin Zihlmann , Dmytro Perekrestenko , Michael Tschannen

Importance: Coronary algorithm for cardiac sub structures and prospective real-time surveillance of cardiac dose exposure. Methods: Retro and prospective study to validate AI auto-segmentation. A 3D UNet was trained on 560 thoracic CT scans…

We propose a hybrid sequential deep learning model to predict the risk of AMD progression in non-exudative AMD eyes at multiple timepoints, starting from short-term progression (3-months) up to long-term progression (21-months). Proposed…

Quantitative Methods · Quantitative Biology 2019-03-01 Imon Banerjee , Luis de Sisternes , Joelle Hallak , Theodore Leng , Aaron Osborne , Mary Durbin , Daniel Rubin

This manuscript proposes a novel methodology for developing an interpretable prediction model for irregular Electrocardiogram (ECG) classification, using features extracted by a 1-D Deconvolutional Neural Network (1-D DNN). Given the…

Applications · Statistics 2024-10-17 Giacomo Lancia , Cristian Spitoni

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Feature subsampling is a core component of random forests and other ensemble methods. While recent theory suggests that this randomization acts solely as a variance reduction mechanism analogous to ridge regularization, these results…

Machine Learning · Statistics 2026-01-06 Xin Chen , Jason M. Klusowski , Yan Shuo Tan , Chang Yu

To predict lung nodule malignancy with a high sensitivity and specificity, we propose a fusion algorithm that combines handcrafted features (HF) into the features learned at the output layer of a 3D deep convolutional neural network (CNN).…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Shulong Li , Panpan Xu , Bin Li , Liyuan Chen , Zhiguo Zhou , Hongxia Hao , Yingying Duan , Michael Folkert , Jianhua Ma , Steve Jiang , Jing Wang

Sparse Neural Networks (SNNs) have emerged as powerful tools for efficient feature selection. Leveraging the dynamic sparse training (DST) algorithms within SNNs has demonstrated promising feature selection capabilities while drastically…