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In inertial microfluidics lift forces cause a particle to migrate across streamlines to specific positions in the cross section of a microchannel. We control the rotational motion of a particle and demonstrate that this allows to manipulate…

Fluid Dynamics · Physics 2014-02-11 Christopher Prohm , Nikolas Zöller , Holger Stark

At finite Reynolds numbers particles migrate across flow streamlines to their equilibrium positions in microchannels. Such a migration is attributed to an inertial lift force, and it is well-known that the equilibrium location of…

Soft Condensed Matter · Physics 2020-01-17 Tatiana V. Nizkaya , Evgeny S. Asmolov , Jens Harting , Olga I. Vinogradova

A flowing pair of particles in inertial microfluidics gives important insights into understanding and controlling the collective dynamics of particles like cells or droplets in microfluidic devices. They are applied in medical cell analysis…

Fluid Dynamics · Physics 2018-05-25 Christian Schaaf , Felix Rühle , Holger Stark

At finite Reynolds numbers, Re, particles migrate across laminar flow streamlines to their equilibrium positions in microchannels. This migration is attributed to a lift force, and the balance between this lift and gravity determines the…

The mechanical deformability of single cells is an important indicator for various diseases such as cancer, blood diseases and inflammation. Lab-on-a-chip devices allow to separate such cells from healthy cells using hydrodynamic forces. We…

Fluid Dynamics · Physics 2019-02-08 Christian Schaaf , Holger Stark

Inertial microfluidic is able to focus and separate particles in microchannels based on the characteristic geometry and intrinsic hydrodynamic effect. Yet, the vertical position of suspended particles in the microchannel cannot be…

Fluid Dynamics · Physics 2022-07-22 Chengliang Xuan , Weiyin Liang , Bing He , Binghai Wen

KEY WORDS suspensions, inertial focusing, particle-laden flows, high Reynolds numbers SHORT SUMMARY The inertial migration of particles in square channel flows at the micro-scale has been deeply investigated in the last two decades. The…

Soft Condensed Matter · Physics 2019-03-20 Yichang Wang , Yanfeng Gao , Pascale Magaud , Lucien Baldas , Christine Lafforgue , Stéphane Colin

Inertial lift forces are exploited within inertial microfluidic devices to position, segregate, and sort particles or droplets. However the forces and their focusing positions can currently only be predicted by numerical simulations, making…

Fluid Dynamics · Physics 2016-07-21 Kaitlyn Hood , Sungyon Lee , Marcus Roper

The identification of cells and particles based on their transport properties in microfluidic devices is crucial for numerous applications in biology and medicine. Neutrally buoyant particles transported in microfluidic channels, migrate…

Finite-size neutrally buoyant particles in a channel flow are known to accumulate at specific equilibrium positions or spots in the channel cross-section if the flow inertia is finite at the particle scale. Experiments in different conduit…

Fluid Dynamics · Physics 2018-10-23 Anupam Gupta , Pascale Magaud , Christine Lafforgue , Micheline Abbas

Viscoelastic microfluidic devices are promising for various microscale procedures such as particle sorting and separation. In this study, we perform three dimensional computational investigation of a particle in a viscoelastic channel flow…

Fluid Dynamics · Physics 2019-10-29 Amir Hossein Raffiee , Arezoo M. Ardekani , Sadegh Dabiri

Understanding particle transport and localisation in porous channels, especially at moderate Reynolds numbers, is relevant for many applications ranging from water reclamation to biological studies. Recently, researchers experimentally…

Fluid Dynamics · Physics 2019-01-30 Mike Garcia , Baskar Ganapathysubramanian , Sumita Pennathur

In recent years, manipulation of particles by inertial microfluidics has attracted significant attention. Most studies focused on inertial focusing of particles suspended within liquid phase, in which the ratio of the density of the…

Fluid Dynamics · Physics 2018-12-07 Maoqiang Jiang , Shizhi Qian , Zhaohui Liu

Particles traveling at high velocities through microfluidic channels migrate from their starting streamlines due to inertial lift forces. Theories predict different scaling laws for these forces and there is little experimental evidence by…

Fluid Dynamics · Physics 2017-07-06 Kaitlyn Hood , Soroush Kahkeshani , Dino Di Carlo , Marcus Roper

Within microcentrifuge devices, a microfluidic vortex separates larger particles from a heterogeneous suspension using inertial migration, a phenomenon that causes particles to migrate across streamlines. The ability to selectively capture…

Fluid Dynamics · Physics 2023-03-14 Samuel Christensen , Marcus Roper

Particles traveling through inertial microfluidic devices migrate to focusing streamlines. We present a numerical method that calculates migration velocities of particles in inertial microfluidic channels of arbitrary cross section by…

Fluid Dynamics · Physics 2022-10-19 Samuel Christensen , Raymond Chu , Christopher R Anderson , Marcus Roper

We observe novel positional control of a colloidal particle in microchannel flow of a nematic liquid crystal. Lattice Boltzmann simulations show multiple equilibrium particle positions, the existence and position of which are tunable using…

Soft Condensed Matter · Physics 2022-09-26 Magdalena Lesniewska , Nigel Mottram , Oliver Henrich

Mixing in numerous medical and chemical applications, involving overly long microchannels, can be enhanced by inducing flow instabilities. The channel length, is thus shortened in the inertial microfluidics regime due to the enhanced…

Fluid Dynamics · Physics 2019-05-13 Saunak Sengupta , Sukhendu Ghosh , Sandeep Saha , Suman Chakraborty

Visual inspections for identifying focusing points in inertial microfluidic flows are prone to misinterpreting stable locations and focusing shifts in the case of non-trivial focusing patterns. We develop and deploy an approach for…

Fluid Dynamics · Physics 2019-01-18 Aditya Kommajosula , Jeong-ah Kim , Wonhee Lee , Baskar Ganapathysubramanian

Efficient sorting of target cells is crucial for advancing cellular research in biology and medical diagnostics. Inertial microfluidics, an emerging technology, offers a promising approach for label-free particle sorting with high…

Fluid Dynamics · Physics 2023-08-04 Sayan Karmakar , Md Safwan Mondal , Anish Pal , Sourav Sarkar
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