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For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…

Molecular Networks · Quantitative Biology 2009-11-13 Matthew Scott , Terence Hwa , Brian Ingalls

Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities…

Molecular Networks · Quantitative Biology 2011-09-30 Pau Rué , Gürol M. Süel , Jordi Garcia-Ojalvo

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

We study a noisy oscillator with pulse delayed feedback, theoretically and in an electronic experimental implementation. Without noise, this system has multiple stable periodic regimes. We consider two types of noise: i) phase noise acting…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 Vladimir Klinshov , Dmitry Shchapin , Otti D'Huys

A new type of noised-induced phase transitions that should occur in systems of elements with motivated behavior is considered. By way of an example, a simple oscillatory system {x,v} with additive white noise is analyzed numerically. A…

Soft Condensed Matter · Physics 2007-05-23 Ihor Lubashevsky , Morteza Hajimahmoodzadeh , Albert Katsnelson , Peter Wagner

Intrinsic or demographic noise has been shown to play an important role in the dynamics of a variety of systems including predator-prey populations, intracellular biochemical reactions, and oscillatory chemical reaction systems, and is…

Statistical Mechanics · Physics 2013-03-14 C. Michael Giver , Bulbul Chakraborty

Networks of globally coupled, noise activated, bistable elements with connection time delays are considered. The dynamics of these systems is studied numerically using a Langevin description and analytically using (1) a Gaussian…

Statistical Mechanics · Physics 2009-11-11 Daniel Huber , Lev Tsimring

We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this…

Molecular Networks · Quantitative Biology 2016-12-21 Alan Veliz-Cuba , Chinmaya Gupta , Matthew R. Bennett , Krešimir Josić , William Ott

We study noise-enhanced frequency mixing in an underdamped micromechanical torsional oscillator. The oscillator is electrostatically driven into bistability by a strong, periodic voltage at frequency $\omega_d$. A second, weak ac voltage is…

Other Condensed Matter · Physics 2007-05-23 H. B. Chan , C. Stambaugh

What input signals will lead to synchrony vs. desynchrony in a group of biological oscillators? This question connects with both classical dynamical systems analyses of entrainment and phase locking and with emerging studies of stimulation…

Dynamical Systems · Mathematics 2015-03-17 Guillaume Lajoie , Eric Shea-Brown

Noise-induced phase transitions are common in various complex systems, from physics to biology. In this article, we investigate the emergence of crucial events in noise-induced phase transition processes and their potential significance for…

Data Analysis, Statistics and Probability · Physics 2023-06-28 Jacob D. Baxley , David R. Lambert , Mauro Bologna , Bruce J. West , Paolo Grigolini

Negative serial correlations in single spike trains are an effective method to reduce the variability of spike counts. One of the factors contributing to the development of negative correlations between successive interspike intervals is…

Neurons and Cognition · Quantitative Biology 2011-10-04 Eugenio Urdapilleta

We investigate the effects of quenched disorder on the coherent response in a driven system of coupled oscillators. In particular, the interplay between quenched noise and periodic driving is explored, with particular attention to the…

Statistical Mechanics · Physics 2009-11-10 H. Hong

We investigate the predictive power of recurrent neural networks for oscillatory systems not only on the attractor, but in its vicinity as well. For this we consider systems perturbed by an external force. This allows us to not merely…

Adaptation and Self-Organizing Systems · Physics 2019-07-02 Rok Cestnik , Markus Abel

The mechanism of phase synchronization between uncoupled limit-cycle oscillators induced by common external impulsive forcing is analyzed. By reducing the dynamics of the oscillator to a random phase map, it is shown that phase…

Adaptation and Self-Organizing Systems · Physics 2007-06-13 H. Nakao , K. Arai , K. Nagai , Y. Tsubo , Y. Kuramoto

The entrainment between weakly-coupled nonlinear oscillators, as well as between complex signals such as those representing physiological activity, is frequently assessed in terms of whether a stable relationship is detectable between the…

Neurons and Cognition · Quantitative Biology 2019-02-27 Ludovico Minati , Natsue Yoshimura , Mattia Frasca , Stanislaw Drozdz , Yasuharu Koike

We study the impact of noise on a neural population rate model of up and down states. Up and down states are typically observed in neuronal networks as a slow oscillation, where the population switches between high and low firing rates…

Neurons and Cognition · Quantitative Biology 2015-04-24 Zachary McCleney , Zachary P. Kilpatrick

We find that feedback control may induce "pseudo" nonlinear dynamics in a damped harmonic oscillator, whose centroid trajectory in the phase space behaves like a classical nonlinear system. Thus, similar to nonlinear amplifiers (e.g.,…

Quantum Physics · Physics 2015-05-14 Jing Zhang , Yu-xi Liu , Re-Bing Wu , Chun-Wen Li , Tzyh-Jong Tarn

In multi-terminal networks, feedback increases the capacity region and helps communication devices to coordinate. In this article, we deepen the relationship between coordination and feedback by considering a point-to-point scenario with an…

Information Theory · Computer Science 2016-11-15 Maël Le Treust

Additive noise is known to produce counter-intuitive behaviors in nonlinear dynamical systems. Previously, it was shown that systems with a deterministic limit cycle can display bistable switching between metastable states in the presence…

Chaotic Dynamics · Physics 2015-01-26 Michael A. Schwemmer , Jay M. Newby