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Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

We propose a genetic algorithm (GA) based method for modifying n-best lists produced by a machine translation (MT) system. Our method offers an innovative approach to improving MT quality and identifying weaknesses in evaluation metrics.…

Computation and Language · Computer Science 2023-06-01 Josef Jon , Ondřej Bojar

For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statistical considerations which clearly show…

Applications · Statistics 2010-10-04 Florian Frommlet , Felix Ruhaltinger , Piotr Twarog , Malgorzata Bogdan

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

In this paper we develop and test algorithmic techniques to estimate genotypes fitnesses by analysis of observed daily frequency data monitoring the long-term evolution of bacterial populations. In particular, we develop a non-linear least…

Populations and Evolution · Quantitative Biology 2020-10-05 Sergey S. Sarkisov , Ilya Timofeyev , Robert Azencott

Verifying the robustness of machine learning models against evasion attacks at test time is an important research problem. Unfortunately, prior work established that this problem is NP-hard for decision tree ensembles, hence bound to be…

Machine Learning · Computer Science 2023-11-14 Stefano Calzavara , Lorenzo Cazzaro , Giulio Ermanno Pibiri , Nicola Prezza

This paper examines the use of a hierarchical coevolutionary genetic algorithm under different partnering strategies. Cascading clusters of sub-populations are built from the bottom up, with higher-level sub-populations optimising larger…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Larry Bull

Trait differences between species may be attributable to natural selection. However, quantifying the strength of evidence for selection acting on a particular trait is a difficult task. Here we develop a population-genetic test for…

Populations and Evolution · Quantitative Biology 2017-08-09 Nico Riedel , Bhavin S. Khatri , Michael Lässig , Johannes Berg

The effective planning and allocation of resources in modern breeding programs is a complex task. Breeding program design and operational management have a major impact on the success of a breeding program and changing parameters such as…

Quantitative Methods · Quantitative Biology 2024-07-25 Azadeh Hassanpour , Johannes Geibel , Henner Simianer , Antje Rohde , Torsten Pook

Resource constrained job scheduling is a hard combinatorial optimisation problem that originates in the mining industry. Off-the-shelf solvers cannot solve this problem satisfactorily in reasonable timeframes, while other solution methods…

Neural and Evolutionary Computing · Computer Science 2024-07-23 Su Nguyen , Dhananjay Thiruvady , Yuan Sun , Mengjie Zhang

In evolutionary algorithms, the fitness of a population increases with time by mutating and recombining individuals and by a biased selection of more fit individuals. The right selection pressure is critical in ensuring sufficient…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Marcus Hutter , Shane Legg

In NeuroEvolution, the topologies of artificial neural networks are optimized with evolutionary algorithms to solve tasks in data regression, data classification, or reinforcement learning. One downside of NeuroEvolution is the large amount…

Neural and Evolutionary Computing · Computer Science 2019-02-12 Jörg Stork , Martin Zaefferer , Thomas Bartz-Beielstein

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

The primary aim of automated performance improvement is to reduce the running time of programs while maintaining (or improving on) functionality. In this paper, Genetic Programming is used to find performance improvements in regular…

Neural and Evolutionary Computing · Computer Science 2017-04-14 Brendan Cody-Kenny , Michael Fenton , Adrian Ronayne , Eoghan Considine , Thomas McGuire , Michael O'Neill

This study explores the application of machine learning-based genetic linguistics for identifying heavy metal response genes in rice (Oryza sativa). By integrating convolutional neural networks and random forest algorithms, we developed a…

Machine Learning · Computer Science 2025-03-24 Ruiqi Yang , Jianxu Wang , Wei Yuan , Xun Wang , Mei Li

Modern pattern recognition tasks use complex algorithms that take advantage of large datasets to make more accurate predictions than traditional algorithms such as decision trees or k-nearest-neighbor better suited to describe simple…

Machine Learning · Statistics 2021-10-14 AGaurav Arwade , Sigurdur Olafsson

In this paper, we develop a set of genetic programming operators and an initialization population process based on concepts of functional programming rewriting for boosting inductive genetic programming. Such genetic operators are used…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Edwin Camilo Cubides , Jonatan Gomez

Accurate and precise crop yield prediction is invaluable for decision making at both farm levels and regional levels. To make yield prediction, crop models are widely used for their capability to simulate hypothetical scenarios. While…

Machine Learning · Computer Science 2024-04-02 Yuji Saikai

As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…

Applications · Statistics 2013-08-15 Deniz Akdemir

We propose a mathematical framework for natural selection in finite populations. Traditionally, many of the selection-based processes used to describe cultural and genetic evolution (such as imitation and birth-death models) have been…

Populations and Evolution · Quantitative Biology 2015-11-18 Alex McAvoy
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