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This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features that make R…

Genomics · Quantitative Biology 2014-01-14 Laurent Gatto , Andy Christoforou

With the agile development process of most academic and corporate entities, designing a robust computational back-end system that can support their ever-changing data needs is a constantly evolving challenge. We propose the implementation…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-07 Conor Flynn , Kristin P. Bennett , John S. Erickson , Aaron Green , Oshani Seneviratne

In managed languages, serialization of objects is typically done in bespoke binary formats such as Protobuf, or markup languages such as XML or JSON. The major limitation of these formats is readability. Human developers cannot read binary…

Software Engineering · Computer Science 2025-12-16 Julian Wachter , Deepika Tiwari , Martin Monperrus , Benoit Baudry

Statistical analysis is the tool of choice to turn data into information, and then information into empirical knowledge. To be valid, the process that goes from data to knowledge should be supported by detailed, rigorous guidelines, which…

Software Engineering · Computer Science 2024-10-03 Carlo A. Furia , Richard Torkar , Robert Feldt

Applications integrating analysis components require a programmable interface which defines statistical operations independently of any programming language. By separating concerns of scientific computing from application and implementation…

Computation · Statistics 2014-06-19 Jeroen Ooms

Many protocol implementations are reactive systems, where the protocol process is in continuous interaction with other processes and the environment. If a bug can be exposed only in a certain state, a fuzzer needs to provide a specific…

Cryptography and Security · Computer Science 2023-06-06 Jinsheng Ba , Marcel Böhme , Zahra Mirzamomen , Abhik Roychoudhury

To increase performance and efficiency, systems use FPGAs as reconfigurable accelerators. A key challenge in designing these systems is partitioning computation between processors and an FPGA. An appropriate division of labor may be…

Hardware Architecture · Computer Science 2021-07-21 Endri Bezati , Mahyar Emami , Jörn Janneck , James Larus

The success of large pretrained Transformers is closely tied to tokenizers, which convert raw input into discrete symbols. Extending these models to graph-structured data remains a significant challenge. In this work, we introduce a graph…

Machine Learning · Computer Science 2026-03-13 Zeyuan Guo , Enmao Diao , Cheng Yang , Chuan Shi

Linking information across sources is fundamental to a variety of analyses in social science, business, and government. While large language models (LLMs) offer enormous promise for improving record linkage in noisy datasets, in many…

Computation and Language · Computer Science 2024-06-26 Abhishek Arora , Melissa Dell

Today's datacenter applications rely on datastores that are required to provide high availability, consistency, and performance. To achieve high availability, these datastores replicate data across several nodes. Such replication is managed…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-25 M. R. Siavash Katebzadeh , Antonios Katsarakis , Boris Grot

When components of a system exchange data, they need to serialise the data so that it can be sent over the network. Then, the recipient has to deserialise the data in order to be able to process it. These steps take time and have an impact…

Programming Languages · Computer Science 2025-04-30 Arthur Jamet , Michael Vollmer

Recent advancements in developing Pre-trained Language Models for Code (Code-PLMs) have urged many areas of Software Engineering (SE) and brought breakthrough results for many SE tasks. Though these models have achieved the state-of-the-art…

Software Engineering · Computer Science 2025-05-19 ZiXiao Zhao , Fatemeh H. Fard

Graphical models provide powerful tools to uncover complicated patterns in multivariate data and are commonly used in Bayesian statistics and machine learning. In this paper, we introduce the R package BDgraph which performs Bayesian…

Machine Learning · Statistics 2019-05-14 Reza Mohammadi , Ernst C. Wit

We propose to use agent-based simulation models for the development of statistical methods in Official Statistics, especially in relation with the new digital data sources. We present a mobile network data simulator which is managed through…

Applications · Statistics 2022-01-21 B. Oancea , D. Salgado , S. Barragan , M. Necula

High-dimensional prediction considers data with more variables than samples. Generic research goals are to find the best predictor or to select variables. Results may be improved by exploiting prior information in the form of co-data,…

Methodology · Statistics 2022-05-17 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

Robust estimation provides essential tools for analyzing data that contain outliers, ensuring that statistical models remain reliable even in the presence of some anomalous data. While robust methods have long been available in R, users of…

Computation · Statistics 2024-11-05 Sarah Leyder , Jakob Raymaekers , Peter J. Rousseeuw , Thomas Servotte , Tim Verdonck

We describe NIMBLE, a system for programming statistical algorithms for general model structures within R. NIMBLE is designed to meet three challenges: flexible model specification, a language for programming algorithms that can use…

Detecting buffer overruns from a source code is one of the most common and yet challenging tasks in program analysis. Current approaches have mainly relied on rigid rules and handcrafted features devised by a few experts, limiting…

Software Engineering · Computer Science 2017-03-08 Min-je Choi , Sehun Jeong , Hakjoo Oh , Jaegul Choo

Random Linear Network Coding (RLNC) has emerged as a powerful tool for robust high-throughput multicast. Projection analysis - a recently introduced technique - shows that the distributed packetized RLNC protocol achieves (order) optimal…

Information Theory · Computer Science 2011-02-17 Bernhard Haeupler , Muriel Médard

Even though in recent years the scale of statistical analysis problems has increased tremendously, many statistical software tools are still limited to single-node computations. However, statistical analyses are largely based on dense…

Computation · Statistics 2016-11-01 Rodrigo Canales , Elmar Peise , Paolo Bientinesi