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Optimization results are one method for understanding neural computation from Nature's perspective and for defining the physical limits on neuron-like engineering. Earlier work looks at individual properties or performance criteria and…

Neurons and Cognition · Quantitative Biology 2017-12-21 William B Levy , Toby Berger , Mustafa Sungkar

Most nervous systems encode information about stimuli in the responding activity of large neuronal networks. This activity often manifests itself as dynamically coordinated sequences of action potentials. Since multiple electrode recordings…

Neurons and Cognition · Quantitative Biology 2011-11-09 Kristina Lisa Klinkner , Cosma Rohilla Shalizi , Marcelo F. Camperi

Precise control of signal propagation in modular neural networks represents a fundamental challenge in computational neuroscience. We establish a framework for identifying optimal control nodes that maximize stimulus transmission between…

Neurons and Cognition · Quantitative Biology 2025-08-18 Bulat Batuev , Arsenii Onuchin , Sergey Sukhov

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

Spiking neural network is a type of artificial neural network in which neurons communicate between each other with spikes. Spikes are identical Boolean events characterized by the time of their arrival. A spiking neuron has internal…

Neural and Evolutionary Computing · Computer Science 2016-02-16 Oleg Y. Sinyavskiy

The generation and conduction of action potentials represents a fundamental means of communication in the nervous system, and is a metabolically expensive process. In this paper, we investigate the energy efficiency of neural systems in a…

Neurons and Cognition · Quantitative Biology 2014-04-23 Lianchun Yu , Liwei Liu

We present a neuronal network model inspired by the Ising model, where each neuron is a binary spin ($s_i = \pm1$) interacting with its neighbors on a 2D lattice. Updates are asynchronous and follow Metropolis dynamics, with a…

Neurons and Cognition · Quantitative Biology 2025-06-10 Sajedeh Sarmastani , Maliheh Ghodrat , Yousef Jamali

Over the brief time intervals available for processing retinal output, roughly 50 to 300 msec, the number of extra spikes generated by individual ganglion cells can be quite variable. Here, computer-generated spike trains were used to…

Neurons and Cognition · Quantitative Biology 2007-09-14 Garrett T. Kenyon

We consider an excitatory population of subthreshold Izhikevich neurons which exhibit noise-induced firings. By varying the coupling strength $J$, we investigate population synchronization between the noise-induced firings which may be used…

Neurons and Cognition · Quantitative Biology 2014-03-06 Sang-Yoon Kim , Woochang Lim

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…

Neurons and Cognition · Quantitative Biology 2016-10-31 Eugenio Urdapilleta

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase-lock…

Neurons and Cognition · Quantitative Biology 2009-11-13 Ramana Dodla , Charles J. Wilson

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang

In network models of spiking neurons, the joint impact of network structure and synaptic parameters on activity propagation is still an open problem. Here we use an information-theoretical approach to investigate activity propagation in…

Neurons and Cognition · Quantitative Biology 2020-04-14 Rodrigo F. O. Pena , Vinicius Lima , Renan O. Shimoura , João P. Novato , Antonio C. Roque

Spike patterns have been reported to encode sensory information in several brain areas. Here we assess the role of specific patterns in the neural code, by comparing the amount of information transmitted with different choices of the…

Quantitative Methods · Quantitative Biology 2009-12-14 Hugo Gabriel Eyherabide , Ines Samengo

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

The dynamics of three mutually coupled cortical neurons with time delays in the coupling are explored numerically and analytically. The neurons are coupled in a line, with the middle neuron sending a somewhat stronger projection to the…

Chaotic Dynamics · Physics 2011-01-25 Alexandra S. Landsman , Ira B. Schwartz

Sensory systems across all modalities and species exhibit adaptation to continuously changing input statistics. Individual neurons have been shown to modulate their response gains so as to maximize information transmission in different…

Neurons and Cognition · Quantitative Biology 2023-06-01 Lyndon R. Duong , Colin Bredenberg , David J. Heeger , Eero P. Simoncelli

Radio communication over interstellar distances is studied, accounting for noise, dispersion, scattering and motion. Large transmitted powers suggest maximizing power efficiency (ratio of information rate to average signal power) as opposed…

Instrumentation and Methods for Astrophysics · Physics 2016-03-01 David G. Messerschmitt

In terms of the long-distance communication of a single neuron, interpulse intervals (IPIs) are a possible alternative to rate and binary codes. As a proxy for IPI, the time-to-spike (TTS) for a neuron can be found in the biophysical and…

Neurons and Cognition · Quantitative Biology 2019-01-15 Chandan Singh , William B. Levy