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Inverse inference, or "brain reading", is a recent paradigm for analyzing functional magnetic resonance imaging (fMRI) data, based on pattern recognition and statistical learning. By predicting some cognitive variables related to brain…

A recent interest in resting state functional magnetic resonance imaging (rsfMRI) lies in subdividing the human brain into anatomically and functionally distinct regions of interest. For example, brain parcellation is often used for…

Despite impressive performance on numerous visual tasks, Convolutional Neural Networks (CNNs) --- unlike brains --- are often highly sensitive to small perturbations of their input, e.g. adversarial noise leading to erroneous decisions. We…

Regularization for denoising in magnetic resonance imaging (MRI) is typically achieved using convex regularization functions. Recently, deep learning techniques have been shown to provide superior denoising performance. However, this comes…

Signal Processing · Electrical Eng. & Systems 2025-08-21 Akash Prabakar , Abhishek Shreekant Bhandiwad , Abijith Jagannath Kamath , Chandra Sekhar Seelamantula

Regularized models are often sensitive to the scales of the features in the data and it has therefore become standard practice to normalize (center and scale) the features before fitting the model. But there are many different ways to…

Machine Learning · Statistics 2025-07-04 Johan Larsson , Jonas Wallin

To learn and reason in the presence of uncertainty, the brain must be capable of imposing some form of regularization. Here we suggest, through theoretical and computational arguments, that the combination of noise with synchronization…

Neurons and Cognition · Quantitative Biology 2013-12-06 Jake Bouvrie , Jean-Jacques Slotine

Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised…

Machine Learning · Computer Science 2012-07-03 Gael Varoquaux , Alexandre Gramfort , Bertrand Thirion

Some prominent discretisation methods such as finite elements provide a way to approximate a function of $d$ variables from $n$ values it takes on the nodes $x_i$ of the corresponding mesh. The accuracy is $n^{-s_a/d}$ in $L^2$-norm, where…

Numerical Analysis · Mathematics 2024-07-19 Camille Pouchol , Marc Hoffmann

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

Modern deep neural networks require a tremendous amount of data to train, often needing hundreds or thousands of labeled examples to learn an effective representation. For these networks to work with less data, more structure must be built…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Reuben Feinman , Brenden M. Lake

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Functional Magnetic Resonance Imaging (fMRI) provides dynamical access into the complex functioning of the human brain, detailing the hemodynamic activity of thousands of voxels during hundreds of sequential time points. One approach…

Neurons and Cognition · Quantitative Biology 2008-01-16 Francois G. Meyer , Greg J. Stephens

Due to developments in instruments and computers, functional observations are increasingly popular. However, effective methodologies for flexibly estimating the underlying trends with valid uncertainty quantification for a sequence of…

Methodology · Statistics 2022-09-22 Tomoya Wakayama , Shonosuke Sugasawa

Functional magnetic resonance imaging (fMRI) is a notoriously noisy measurement of brain activity because of the large variations between individuals, signals marred by environmental differences during collection, and spatiotemporal…

Regularization is crucial to the success of many practical deep learning models, in particular in a more often than not scenario where there are only a few to a moderate number of accessible training samples. In addition to weight decay,…

Machine Learning · Computer Science 2018-08-07 Che-Wei Huang , Shrikanth S. Narayanan

We develop a new statistical method for estimating functional connectivity between neurophysiological signals represented by a multivariate time series. We use partial coherence as the measure of functional connectivity. Partial coherence…

Applications · Statistics 2011-08-17 Mark Fiecas , Hernando Ombao

In this paper, we study norm-based regularization methods for neural networks. We compare existing penalization approaches and introduce two regularization strategies that extend classical ridge- and lasso-type penalties to neural network…

Machine Learning · Statistics 2026-05-04 Muhammad Qasim , Farrukh Javed

We study in this paper a smoothness regularization method for functional linear regression and provide a unified treatment for both the prediction and estimation problems. By developing a tool on simultaneous diagonalization of two positive…

Statistics Theory · Mathematics 2012-11-13 Ming Yuan , T. Tony Cai

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

Methodology · Statistics 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson
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