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The demise of Moore's Law and Dennard Scaling has revived interest in specialized computer architectures and accelerators. Verification and testing of this hardware depend heavily upon cycle-accurate simulation of register-transfer-level…

Hardware Architecture · Computer Science 2024-02-09 Mahyar Emami , Sahand Kashani , Keisuke Kamahori , Mohammad Sepehr Pourghannad , Ritik Raj , James R. Larus

B-spline based orbital representations are widely used in Quantum Monte Carlo (QMC) simulations of solids, historically taking as much as 50% of the total run time. Random accesses to a large four-dimensional array make it challenging to…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-10 Amrita Mathuriya , Ye Luo , Anouar Benali , Luke Shulenburger , Jeongnim Kim

Today's unrelenting increase in demand for information processing creates the need for novel computing concepts. Reservoir computing is such a concept that lends itself particularly well to photonic hardware implementations. Over recent…

Emerging Technologies · Computer Science 2016-12-28 Akram Akrout , Arno Bouwens , François Duport , Quentin Vinckier , Marc Haelterman , Serge Massar

Parallel processing is a principle which enables simultaneous implementation of anesthesia induction and operating room (OR) turnover with the aim of improving OR utilization. In this article, we study the problem of scheduling surgeries…

Optimization and Control · Mathematics 2022-01-03 Batuhan Celik , Serhat Gul , Melih Celik

Modern parallel computing devices, such as the graphics processing unit (GPU), have gained significant traction in scientific and statistical computing. They are particularly well-suited to data-parallel algorithms such as the particle…

Computation · Statistics 2015-06-12 Lawrence M. Murray , Anthony Lee , Pierre E. Jacob

Computational protein structure determination involves optimization in a problem space much too large to exhaustively search. Existing approaches include optimization algorithms such as gradient descent and simulated annealing, but these…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-04 Michael Bryson , Xijiang Miao , Homayoun Valafar

The simulator is an R package that streamlines the process of performing simulations by creating a common infrastructure that can be easily used and reused across projects. Methodological statisticians routinely write simulations to compare…

Computation · Statistics 2016-07-04 Jacob Bien

We present a shared-memory parallelization of flow-based refinement, which is considered the most powerful iterative improvement technique for hypergraph partitioning at the moment. Flow-based refinement works on bipartitions, so current…

Data Structures and Algorithms · Computer Science 2022-01-06 Lars Gottesbüren , Tobias Heuer , Peter Sanders

Standard gradient descent methods yield point estimates with no measure of confidence. This limitation is acute in overparameterized and low-data regimes, where models have many parameters relative to available data and can easily overfit.…

Machine Learning · Computer Science 2025-08-22 Carlos Stein Brito

We propose new sequential sorting operations by adapting techniques and methods used for designing parallel sorting algorithms. Although the norm is to parallelize a sequential algorithm to improve performance, we adapt a contrarian…

Data Structures and Algorithms · Computer Science 2016-09-01 Alexandros V Gerbessiotis

We report on a broader evaluation of statistical bootstrap resampling methods as a tool for pixel-level calibration and imaging fidelity assessment in radio interferometry. Pixel-level imaging fidelity assessment is a challenging problem,…

Instrumentation and Methods for Astrophysics · Physics 2015-05-14 Athol Kemball , Adam Martinsek , Modhurita Mitra , Hsin-Fang Chiang

RNA-sequencing has revolutionized biomedical research and, in particular, our ability to study gene alternative splicing. The problem has important implications for human health, as alternative splicing may be involved in malfunctions at…

Applications · Statistics 2015-12-11 David Rossell , Camille Stephan-Otto Attolini , Manuel Kroiss , Almond Stöcker

State machine replication protocols, like MultiPaxos and Raft, are a critical component of many distributed systems and databases. However, these protocols offer relatively low throughput due to several bottlenecked components. Numerous…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-05-18 Michael Whittaker , Ailidani Ailijiang , Aleksey Charapko , Murat Demirbas , Neil Giridharan , Joseph M. Hellerstein , Heidi Howard , Ion Stoica , Adriana Szekeres

High-performance, multi-core processors are the key to accelerating workloads in several application domains. To continue to scale performance at the limit of Moore's Law and Dennard scaling, software and hardware designers have turned to…

Hardware Architecture · Computer Science 2023-10-27 Changxi Liu , Alen Sabu , Akanksha Chaudhari , Qingxuan Kang , Trevor E. Carlson

Joint modeling has become increasingly popular for characterizing the association between one or more longitudinal biomarkers and competing risks time-to-event outcomes. However, semiparametric multivariate joint modeling for large-scale…

Methodology · Statistics 2025-06-17 Shanpeng Li , Emily Ouyang , Jin Zhou , Xinping Cui , Gang Li

The use of Model Predictive Control in industry is steadily increasing as more complicated problems can be addressed. Due to that online optimization is usually performed, the main bottleneck with Model Predictive Control is the relatively…

Optimization and Control · Mathematics 2014-01-31 Isak Nielsen , Daniel Axehill

Statistical procedures such as Bayes factor model selection and Bayesian model averaging require the computation of normalizing constants (e.g., marginal likelihoods). These normalizing constants are notoriously difficult to obtain, as they…

Computation · Statistics 2018-09-19 Quentin F. Gronau , Henrik Singmann , Eric-Jan Wagenmakers

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

As modern analogue/mixed-signal design increasingly relies on optimization-in-the-loop flows, such as AI and LLM-based sizing agents that repeatedly invoke SPICE-efficient, accurate high-performance simulators have become an indispensable…

Hardware Architecture · Computer Science 2026-04-06 Xuanhao Bao , Danial Chitnis

The paper introduces PDSP-Bench, a novel benchmarking system designed for a systematic understanding of performance of parallel stream processing in a distributed environment. Such an understanding is essential for determining how Stream…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-16 Pratyush Agnihotri , Boris Koldehofe , Roman Heinrich , Carsten Binnig , Manisha Luthra