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The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…

Populations and Evolution · Quantitative Biology 2015-05-11 Connor O. McCoy , Trevor Bedford , Vladimir N. Minin , Philip Bradley , Harlan Robins , Frederick A. Matsen

We consider string matching with variable length gaps. Given a string $T$ and a pattern $P$ consisting of strings separated by variable length gaps (arbitrary strings of length in a specified range), the problem is to find all ending…

Data Structures and Algorithms · Computer Science 2011-10-14 Philip Bille , Inge Li Goertz , Hjalte Wedel Vildhøj , David Kofoed Wind

We investigate the problem of generating common randomness (CR) from finite compound sources aided by unidirectional communication over rate-limited perfect channels. The two communicating parties, often referred to as terminals, observe…

Information Theory · Computer Science 2024-01-26 Rami Ezzine , Moritz Wiese , Christian Deppe , Holger Boche

We observe the propagation of information in a system of self-replicating strings of code (``Artificial Life'') as a function of fitness and mutation rate. Comparison with theoretical predictions based on the reaction-diffusion equation…

adap-org · Physics 2008-02-03 Johan Chu , Chris Adami

When considering binary strings, it's natural to wonder how many distinct subsequences might exist in a given string. Given that there is an existing algorithm which provides a straightforward way to compute the number of distinct…

Combinatorics · Mathematics 2023-06-22 Yonah Biers-Ariel , Anant Godbole , Elizabeth Kelley

Each human genome is a 3 billion base pair set of encoding instructions. Decoding the genome using deep learning fundamentally differs from most tasks, as we do not know the full structure of the data and therefore cannot design…

Machine Learning · Computer Science 2016-05-24 Laura Deming , Sasha Targ , Nate Sauder , Diogo Almeida , Chun Jimmie Ye

Labeled infinite trees provide combinatorial interpretations for many integer sequences generated by nested recurrence relations. Typically, such sequences are monotone increasing. Several of these sequences also have straightforward…

Combinatorics · Mathematics 2022-11-07 Nathan Fox

The study of regenerating codes has advanced tremendously in recent years. However, most known constructions require large field size, and hence may be hard to implement in practice. By using notions from the theory of extension fields, we…

Information Theory · Computer Science 2016-09-22 Netanel Raviv

In this paper we present a model containing modifications to the Signal-passing Tile Assembly Model (STAM), a tile-based self-assembly model whose tiles are capable of activating and deactivating glues based on the binding of other glues.…

Emerging Technologies · Computer Science 2022-03-30 Andrew Alseth , Daniel Hader , Matthew J. Patitz

In modern neuroscience, memory has been postulated to stored in neural circuits as sequential spike train and Reverberation is one of the specific example.Former research has made much progress on phenomenon description. However, the…

Neurons and Cognition · Quantitative Biology 2022-11-29 Yi Ren , Yanyang Xiao , Guo-Qiang Bi , Pek-Ming Lau

Motivation: Gene regulatory interactions are of fundamental importance to various biological functions and processes. However, only a few previous computational studies have claimed success in revealing genome-wide regulatory landscapes…

Molecular Networks · Quantitative Biology 2017-02-09 Shupeng Gui , Rui Chen , Liang Wu , Ji Liu , Hongyu Miao

DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA…

Biomolecules · Quantitative Biology 2015-11-10 Stephanie Johnson , Martin Lindén , Rob Phillips

P systems with active membranes were used to generate languages, in the sense of languages associated with the structure of membrane systems. Here, we analyze the power of P systems with membrane creation and dissolution restricted to…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-08-18 Rama Raghavan , H. Ramesh , Marian Gheorghe , Shankara Narayanan Krishna

Reproducibility of modeling is a problem that exists for any machine learning practitioner, whether in industry or academia. The consequences of an irreproducible model can include significant financial costs, lost time, and even loss of…

Machine Learning · Computer Science 2018-10-11 Peter Sugimura , Florian Hartl

It takes several years for the developing brain of a baby to fully master word repetition-the task of hearing a word and repeating it aloud. Repeating a new word, such as from a new language, can be a challenging task also for adults.…

Computation and Language · Computer Science 2025-06-17 Daniel Dager , Robin Sobczyk , Emmanuel Chemla , Yair Lakretz

In the trace reconstruction problem, the goal is to reconstruct an unknown string $x$ of length $n$ from multiple traces obtained by passing $x$ through the deletion channel. In the relaxed problem of $approximate$ trace reconstruction, the…

Probability · Mathematics 2021-07-15 Zachary Chase , Yuval Peres

Computer simulations of complex population genetic models are an essential tool for making sense of the large-scale datasets of multiple genome sequences from a single species that are becoming increasingly available. A widely used approach…

Populations and Evolution · Quantitative Biology 2026-04-23 Parul Johri , Fanny Pouyet , Brian Charlesworth

In this work we seek clusters of genomic words in human DNA by studying their inter-word lag distributions. Due to the particularly spiked nature of these histograms, a clustering procedure is proposed that first decomposes each…

Applications · Statistics 2021-01-13 Ana Helena Tavares , Jakob Raymaekers , Peter J. Rousseeuw , Paula Brito , Vera Afreixo

We study the complexity of the problem of searching for a set of patterns that separate two given sets of strings. This problem has applications in a wide variety of areas, most notably in data mining, computational biology, and in…

Computational Complexity · Computer Science 2016-12-20 Giuseppe Lancia , Luke Mathieson , Pablo Moscato

Recursive processing in sentence comprehension is considered a hallmark of human linguistic abilities. However, its underlying neural mechanisms remain largely unknown. We studied whether a modern artificial neural network trained with…

Computation and Language · Computer Science 2021-05-04 Yair Lakretz , Dieuwke Hupkes , Alessandra Vergallito , Marco Marelli , Marco Baroni , Stanislas Dehaene
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