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Calculating free energies is an important and notoriously difficult task for molecular simulations. The rapid increase in computational power has made it possible to probe increasingly complex systems, yet extracting accurate free energies…

Chemical Physics · Physics 2014-07-29 Viveca Lindahl , Jack Lidmar , Berk Hess

Frailty is a geriatric syndrome associated with the lack of physiological reserve and consequent adverse outcomes (therapy complications and death) in older adults. Recent research has shown associations between heart rate (HR) dynamics (HR…

Quantitative Methods · Quantitative Biology 2023-03-27 Patricio Arrué , Kaveh Laksari , Nima Toosizadeh

We propose an extensive framework for additive regression models for correlated functional responses, allowing for multiple partially nested or crossed functional random effects with flexible correlation structures for, e.g., spatial,…

Methodology · Statistics 2013-11-26 Fabian Scheipl , Ana-Maria Staicu , Sonja Greven

One of the major research questions regarding human microbiome studies is the feasibility of designing interventions that modulate the composition of the microbiome to promote health and cure disease. This requires extensive understanding…

Methodology · Statistics 2021-11-18 Matthew D. Koslovsky , Kristi L. Hoffman , Carrie R. Daniel , Marina Vannucci

We develop a framework to uncover and analyze dynamical anomalies from massive, nonlinear and non-stationary time series data. The framework consists of three steps: preprocessing of massive data sets to eliminate erroneous data segments,…

Medical Physics · Physics 2016-12-26 Liang Huang , Xuan Ni , William L. Ditto , Mark Spano , Paul R. Carney , Ying-Cheng Lai

The importance of sleep is paramount for maintaining physical, emotional and mental wellbeing. Though the relationship between sleep and physical activity is known to be important, it is not yet fully understood. The explosion in popularity…

Childhood overweight and obesity is one of the main health problems in the world since it is related to the early appearance of different diseases, in addition to being a risk factor for later developing obesity in adulthood with its health…

Subjective wellness data can provide important information on the well-being of athletes and be used to maximize player performance and detect and prevent against injury. Wellness data, which are often ordinal and multivariate, include…

Applications · Statistics 2020-05-20 Erin M. Schliep , Toryn L. J. Schafer , Matthew Hawkey

Existing work in human activity detection classifies physical activities using a single fixed-length subset of a sensor signal. However, temporally consecutive subsets of a sensor signal are not utilized. This is not optimal for classifying…

Neural and Evolutionary Computing · Computer Science 2018-12-06 Niko Reunanen , Ville Könönen , Hermanni Hälvä , Jani Mäntyjärvi , Arttu Lämsä , Jussi Liikka

A major challenge in neuroimaging is understanding the mapping of neurophysiological dynamics onto cognitive functions. Traditionally, these maps have been constructed by examining changes in the activity magnitude of regions related to…

Wearable electronics are often used for estimating the energy expenditure of the user based on heart rate measurement. While heart rate is a good predictor of calorie consumption at high intensities, it is less precise at low intensity…

Signal Processing · Electrical Eng. & Systems 2020-05-11 Saku Levikari , Antti Immonen , Mikko Kuisma , Heikki Peltonen , Mika Silvennoinen , Heikki Kyrolainen , Pertti Silventoinen

Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Yuwei Zheng , Zijian Gao , Yuting Shen , Jiadong Zhang , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

The way we eat and what we eat, the way we move and the way we sleep significantly impact the risk of becoming obese. These aspects of behavior decompose into several personal behavioral elements including our food choices, eating place…

Computers and Society · Computer Science 2019-11-20 Christos Diou , Ioannis Sarafis , Vasileios Papapanagiotou , Ioannis Ioakimidis , Anastasios Delopoulos

Functional data are often extremely high-dimensional and exhibit strong dependence structures but can often prove valuable for both prediction and inference. The literature on functional data analysis is well developed; however, there has…

Methodology · Statistics 2020-11-09 Paul A. Parker , Scott H. Holan

Varying coefficient models are widely used to characterize dynamic associations between longitudinal outcomes and covariates. Existing work on varying coefficient models, however, all assumes that observation times are independent of the…

Methodology · Statistics 2026-01-27 Yu Gu , Yangjianchen Xu , Peijun Sang

Research on the growth of online tagging systems not only is interesting in its own right, but also yields insights for website management and semantic web analysis. Traditional models that describing the growth of online systems can be…

Information Retrieval · Computer Science 2015-05-20 Lingfei Wu

Machine learning models excel with abundant annotated data, but annotation is often costly and time-intensive. Active learning (AL) aims to improve the performance-to-annotation ratio by using query methods (QMs) to iteratively select the…

Machine Learning · Computer Science 2026-02-17 Hannes Kath , Thiago S. Gouvêa , Daniel Sonntag

Advanced wearable sensor devices have enabled the recording of vast amounts of movement data from individuals regarding their physical activities. This data offers valuable insights that enhance our understanding of how physical activities…

Software Engineering · Computer Science 2024-08-20 Thomas Peroutka , Ilir Murturi , Praveen Kumar Donta , Schahram Dustdar

Phobias significantly impact the quality of life of affected persons. Two methods of assessing anxiety responses are questionnaires and behavioural avoidance tests (BAT). While these can be used in a clinical environment they only record…

Human-Computer Interaction · Computer Science 2025-07-21 Florian Grensing , Vanessa Schmücker , Anne Sophie Hildebrand , Tim Klucken , Maria Maleshkova

When the study variable is functional and storage capacities are limited or transmission costs are high, selecting with survey sampling techniques a small fraction of the observations is an interesting alternative to signal compression…

Statistics Theory · Mathematics 2013-02-15 Hervé Cardot , Camelia Goga , Pauline Lardin
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