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The firing dynamics of biological neurons in mathematical models is often determined by the model's parameters, representing the neurons' underlying properties. The parameter estimation problem seeks to recover those parameters of a single…

Neurons and Cognition · Quantitative Biology 2022-10-05 Long Le , Yao Li

There have been two separate lines of work on estimating Ising models: (1) estimating them from multiple independent samples under minimal assumptions about the model's interaction matrix; and (2) estimating them from one sample in…

Statistics Theory · Mathematics 2020-12-11 Yuval Dagan , Constantinos Daskalakis , Nishanth Dikkala , Anthimos Vardis Kandiros

We present a short introduction into the framework of piecewise deterministic Markov processes. We illustrate the abstract mathematical setting with a series of examples related to dispersal of biological systems, cell cycle models, gene…

Probability · Mathematics 2015-12-08 Ryszard Rudnicki , Marta Tyran-Kaminska

We study variable selection (also called support recovery) in high-dimensional sparse linear regression when one has external information on which variables are likely to be associated with the response. Consistent recovery is only possible…

Statistics Theory · Mathematics 2026-02-16 Paul Rognon-Vael , David Rossell , Piotr Zwiernik

Many causal systems such as biological processes in cells can only be observed indirectly via measurements, such as gene expression. Causal representation learning -- the task of correctly mapping low-level observations to latent causal…

Machine Learning · Computer Science 2025-10-31 Elliot Layne , Jason Hartford , Sébastien Lachapelle , Mathieu Blanchette , Dhanya Sridhar

Sparse Gaussian processes and various extensions thereof are enabled through inducing points, that simultaneously bottleneck the predictive capacity and act as the main contributor towards model complexity. However, the number of inducing…

Machine Learning · Computer Science 2021-07-27 Anders Kirk Uhrenholt , Valentin Charvet , Bjørn Sand Jensen

We address the problem of estimating unknown model parameters and state variables in stochastic reaction processes when only sparse and noisy measurements are available. Using an asymptotic system size expansion for the backward equation we…

Data Analysis, Statistics and Probability · Physics 2010-07-02 Andreas Ruttor , Manfred Opper

In large venues like shopping malls and airports, knowledge on the indoor populations fuels applications such as business analytics, venue management, and safety control. In this work, we provide means of modeling populations in partitions…

Databases · Computer Science 2024-10-30 Xiao Li , Huan Li , Hua Lu , Christian S. Jensen

Dynamic community detection concerns inferring how community memberships evolve over time, including the emergence, persistence, merging, and dissolution of groups in temporal networks. We propose a Bayesian nonparametric model for…

Methodology · Statistics 2026-04-09 Xenia Miscouridou , Francesca Panero , Antreas Laos

This work proposes a general framework for capturing noise-driven transitions in spatially extended non-equilibrium systems and explains the emergence of coherent patterns beyond the instability onset. The framework relies on stochastic…

Dynamical Systems · Mathematics 2024-12-16 Mickaël D. Chekroun , Honghu Liu , James C. McWilliams

Markovian memory embedded in a binary system is shaping its evolution on the basis of its current state and introduces either clustering or dispersion of binary states. The consequence is directly observed in the lengthening or shortening…

Applications · Statistics 2008-02-18 Fotini Pallikari , Nikitas Papasimakis

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

To understand how rich dynamics emerge in neural populations, we require models exhibiting a wide range of activity patterns while remaining interpretable in terms of connectivity and single-neuron dynamics. However, it has been challenging…

Neurons and Cognition · Quantitative Biology 2020-03-10 Alexandre René , André Longtin , Jakob H. Macke

In cluster analysis interest lies in probabilistically capturing partitions of individuals, items or observations into groups, such that those belonging to the same group share similar attributes or relational profiles. Bayesian posterior…

Methodology · Statistics 2017-03-23 Riccardo Rastelli , Nial Friel

Biological systems are characterized by the ubiquitous roles of weak, that is, non-covalent molecular interactions, small, often very small, numbers of specific molecules per cell, and Brownian motion. These combine to produce stochastic…

Cell Behavior · Quantitative Biology 2023-04-27 Michael W. Klymkowsky

The aim of this work is to learn models of population dynamics of physical systems that feature stochastic and mean-field effects and that depend on physics parameters. The learned models can act as surrogates of classical numerical models…

Machine Learning · Statistics 2024-10-28 Jules Berman , Tobias Blickhan , Benjamin Peherstorfer

Stochastic fluctuations of molecule numbers are ubiquitous in biological systems. Important examples include gene expression and enzymatic processes in living cells. Such systems are typically modelled as chemical reaction networks whose…

Quantitative Methods · Quantitative Biology 2017-01-13 David Schnoerr , Guido Sanguinetti , Ramon Grima

Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system…

Molecular Networks · Quantitative Biology 2008-09-18 Vahid Shahrezaei , Julien F Ollivier , Peter S Swain

Success in modeling complex phenomena such as human perception hinges critically on the availability of data and computational power. Significant progress has been made in modeling such phenomena using probabilistic methods, particularly in…

Data Analysis, Statistics and Probability · Physics 2019-02-20 Danh-Tai Hoang , Juyong Song , Vipul Periwal , Junghyo Jo

The goal of this paper is to provide mathematically rigorous tools for modelling the evolution of a community of interacting individuals. We model the population by a measure space where the measure determines the abundance of individual…

Probability · Mathematics 2017-05-17 Thomas Cass , Terry Lyons