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This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are…

Emerging Technologies · Computer Science 2020-12-29 Mehmet Sukru Kuran , H. Birkan Yilmaz , Ilker Demirkol , Nariman Farsad , Andrea Goldsmith

In molecular communication (MC), molecules are released from the transmitter to convey information. This paper considers a realistic molecule shift keying (MoSK) scenario with two species of molecule in two reservoirs, where the molecules…

Information Theory · Computer Science 2024-04-04 Dongliang Jing , Lin Lin , Andrew W. Eckford

Channel memory and inter-symbol interference (ISI) are harmful factors in diffusion-based molecular communication (DBMC) between bionanosensors. To tackle these problems, this paper proposes a lightweight ISI-mitigating coding scheme to…

Information Theory · Computer Science 2023-05-24 Dongliang Jing , Andrew W. Eckford

In this paper, we design matched filters for diffusive molecular communication systems taking into account the following impairments: signal-dependent diffusion noise, inter-symbol interference (ISI), and external interfering molecules. The…

Information Theory · Computer Science 2017-05-05 Vahid Jamali , Arman Ahmadzadeh , Robert Schober

This paper presents a novel physics-based model for signal propagation in closed-loop molecular communication (MC) systems, which are particularly relevant for many envisioned biomedical applications, such as health monitoring or drug…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Lukas Brand , Fardad Vakilipoor , Sören Botsch , Timo Jakumeit , Sebastian Lotter , Robert Schober , Maximilian Schäfer

In Molecular Communications via Diffusion (MCvD), messenger molecules are emitted by a transmitter and propagate randomly through the fluidic environment. In biological systems, the environment can be considered a bounded space, surrounded…

Information Theory · Computer Science 2024-04-29 Anil Kamber , H. Birkan Yilmaz , Ali Emre Pusane , Tuna Tugcu

This paper considers the impact of external noise sources, including interfering transmitters, on a diffusive molecular communication system, where the impact is measured as the number of noise molecules expected to be observed at a passive…

Information Theory · Computer Science 2015-11-20 Adam Noel , Karen C. Cheung , Robert Schober

This letter introduces a novel algorithm for generating codebooks in molecular communications (MC). The proposed algorithm utilizes character entropy to effectively mitigate inter-symbol interference (ISI) during MC via diffusion. Based on…

Information Theory · Computer Science 2023-06-07 Haewoong Hyun Changmin Lee , Miaowen Wen , Sang-Hyo Kim , Chan-Byoung Chae

In this letter, we consider a 3D molecular communication via diffusion system (MCvDS) with a single point transmitter and multiple fully-absorbing spherical receivers whose centers are distributed as a Poisson point process (PPP) in the…

Information Theory · Computer Science 2020-08-20 Nithin V. Sabu , Abhishek K. Gupta

This paper focuses on molecular communication (MC) systems using two types of signaling molecules which may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can…

Information Theory · Computer Science 2019-07-25 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

Inter-symbol interference (ISI) with heteroscedastic, or state-dependent, noise is a defining feature of molecular communication via diffusion (MCvD). However, such noise variance dependency across ISI states has not been systematically…

Information Theory · Computer Science 2026-03-09 Erencem Ozbey , H. Birkan Yilmaz , Chan-Byoung Chae

Joint detection and decoding (JDD) achieves rates based on information theory but is too complex to implement for many channels with memory or nonlinearities. Successive interference cancellation (SIC) at the receiver, combined with…

Information Theory · Computer Science 2025-01-15 Alex Jäger , Gerhard Kramer

Consider impersonation attack by an active malicious nano node (Eve) on a diffusion based molecular communication (DbMC) system---Eve transmits during the idle slots to deceive the nano receiver (Bob) that she is indeed the legitimate nano…

Cryptography and Security · Computer Science 2019-07-19 Sidra Zafar , Waqas Aman , Muhammad Mahboob Ur Rahman , Akram Alomainy , Qammer H. Abbasi

Diffusive molecular communications (DiMC) have recently gained attention as a candidate for nano- to micro- and macro-scale communications due to its simplicity and energy efficiency. As signal propagation is solely enabled by Brownian…

Information Theory · Computer Science 2021-01-11 Mustafa Can Gursoy , Masoumeh Nasiri-Kenari , Urbashi Mitra

This paper studies microfluidic molecular communication receivers with finite-capacity Langmuir adsorption driven by an effective surface concentration. In the reaction-limited regime, we derive a closed-form single-pulse response kernel…

Signal Processing · Electrical Eng. & Systems 2026-01-19 Ruifeng Zheng , Pengjie Zhou , Pit Hofmann , Martín Schottlender , Fatima Rani , Juan A. Cabrera , Frank H. P. Fitzek

Digital receivers are required to recover the transmitted symbols from their observed channel output. In multiuser multiple-input multiple-output (MIMO) setups, where multiple symbols are simultaneously transmitted, accurate symbol…

Signal Processing · Electrical Eng. & Systems 2020-06-17 Nir Shlezinger , Rong Fu , Yonina C. Eldar

Molecular communication has a key role to play in future medical applications, including detecting, analyzing, and addressing infectious disease outbreaks. Overcoming inter-symbol interference (ISI) is one of the key challenges in the…

Information Theory · Computer Science 2022-04-20 Xuan Chen , Miaowen Wen , Fei Ji , Yu Huang , Yuankun Tang , Andrew W. Eckford

We consider channels affected by intersymbol interference with reduced-complexity, mutual information optimized, channel-shortening detection. For such settings, we optimize the transmit filter, taking into consideration the reduced…

Information Theory · Computer Science 2013-10-24 Andrea Modenini , Fredrik Rusek , Giulio Colavolpe

Molecular communication (MC) enables information exchange at the nano- and microscale, with applications in areas like drug delivery and health monitoring. These event-driven scenarios often require alternatives to traditional transmission.…

Information Theory · Computer Science 2025-06-18 Yaning Zhao , Luca Miszewski , Christian Deppe , Massimiliano Pierobon

Data transmission rate in molecular communication systems can be improved by using multiple transmitters and receivers. In molecular multiple-input multiple-output (MIMO) systems which use only single type of molecules, the performance at…

Information Theory · Computer Science 2019-04-23 Nithin V. Sabu , Neeraj Varshney , Abhishek K. Gupta