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Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

Chemical Physics · Physics 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

Markov decision process models and algorithms can be used to identify optimal policies for dispatching ambulances to spatially distributed customers, where the optimal policies indicate the ambulance to dispatch to each customer type in…

Optimization and Control · Mathematics 2023-03-03 Laura A. Albert

The last decade has seen max-stable processes emerge as a common tool for the statistical modeling of spatial extremes. However, their application is complicated due to the unavailability of the multivariate density function, and so…

Methodology · Statistics 2009-02-23 Simone A. Padoan , Mathieu Ribatet , Scott A. Sisson

We consider two classes of irreducible Markovian arrival processes specified by the matrices $C$ and $D$. The Markov Modulated Poison Process (MMPP) and the Markovian Switched Poison Process (MSPP). The former exhibits a diagonal $D$ while…

Probability · Mathematics 2019-05-07 Azam Asanjarani , Yoni Nazarathy

Expectation Maximization (EM) is among the most popular algorithms for estimating parameters of statistical models. However, EM, which is an iterative algorithm based on the maximum likelihood principle, is generally only guaranteed to find…

Statistics Theory · Mathematics 2016-08-30 Ji Xu , Daniel Hsu , Arian Maleki

We consider a novel, analytical queuing model for vehicle coordination at signal-free intersections. Vehicles arrive at an intersection according to Poisson processes, and the crossing times are constants dependent of vehicle types. We use…

Systems and Control · Electrical Eng. & Systems 2020-09-29 Hanwen Dai , Li Jin

We propose Markov two-components processes (M2CP) as a probabilistic model of asynchronous systems based on the trace semantics for concurrency. Considering an asynchronous system distributed over two sites, we introduce concepts and tools…

Systems and Control · Computer Science 2015-07-01 Samy Abbes

This paper presents a novel two-step approach for the fundamental problem of learning an optimal map from one distribution to another. First, we learn an optimal transport (OT) plan, which can be thought as a one-to-many map between the two…

Probabilistic circuits (PCs) such as sum-product networks efficiently represent large multi-variate probability distributions. They are preferred in practice over other probabilistic representations such as Bayesian and Markov networks…

Machine Learning · Computer Science 2024-02-07 Shivvrat Arya , Tahrima Rahman , Vibhav Gogate

State estimation in robotic systems presents significant challenges, particularly due to the prevalence of multimodal posterior distributions in real-world scenarios. One effective strategy for handling such complexity is to compute maximum…

Robotics · Computer Science 2026-01-27 Min-Won Seo , Solmaz S. Kia

This paper proposes a novel max-pressure (MP) algorithm that incorporates pedestrian traffic into the MP control architecture. Pedestrians are modeled as being included in one of two groups: those walking on sidewalks and those queued at…

Systems and Control · Electrical Eng. & Systems 2024-09-26 Hao Liu , Vikash V. Gayah , Michael Levin

The application of current generation computing machines in safety-centric applications like implantable biomedical chips and automobile safety has immensely increased the need for reviewing the worst-case error behavior of computing…

Information Theory · Computer Science 2021-08-23 Karthikeyan Lingasubramanian , Syed M. Alam , Sanjukta Bhanja

The maximum-likelihood method for quantum estimation is reviewed and applied to the reconstruction of density matrix of spin and radiation as well as to the determination of several parameters of interest in quantum optics.

Quantum Physics · Physics 2009-11-07 M. G. A. Paris , G. M. D'Ariano , M. F. Sacchi

Understanding transport capacity in intermittently connected mobile networks (ICMN) is crucial since different applications have different interactivity and bandwidth requirements. One practical issue is how to transform an application's…

Networking and Internet Architecture · Computer Science 2010-01-21 John Whitbeck , Vania Conan , Marcelo Dias de Amorim

Maximum Likelihood Estimation (MLE) and Likelihood Ratio Test (LRT) are widely used methods for estimating the transition probability matrix in Markov chains and identifying significant relationships between transitions, such as equality.…

Methodology · Statistics 2024-06-04 Yining Zhou , Ming Gao , Yiting Chen , Xiaoping Shi

Airspace models have played an important role in the development and evaluation of aircraft collision avoidance systems for both manned and unmanned aircraft. As Urban Air Mobility (UAM) systems are being developed, we need new encounter…

Artificial Intelligence · Computer Science 2019-07-15 Sydney M. Katz , Anne-Claire Le Bihan , Mykel J. Kochenderfer

Consider the batch-arrival $GI^X/M/c/N$ model with $c$ servers, general inter-arrival batch times, finite buffer, and exponential service times. Inter-arrival batch times, batch sizes, and service times are $i.i.d.$ and independent of each…

Probability · Mathematics 2022-12-20 Muhammad El-Taha , Thomas Michaud

Motivated by disease progression-related studies, we propose an estimation method for fitting general non-homogeneous multi-state Markov models. The proposal can handle many types of multi-state processes, with several states and various…

Methodology · Statistics 2024-07-22 Alessia Eletti , Giampiero Marra , Rosalba Radice

We present two new methods for estimating the order (memory depth) of a finite alphabet Markov chain from observation of a sample path. One method is based on entropy estimation via recurrence times of patterns, and the other relies on a…

Statistics Theory · Mathematics 2007-06-13 Yuval Peres , Paul Shields

Markov networks are frequently used in sciences to represent conditional independence relationships underlying observed variables arising from a complex system. It is often of interest to understand how an underlying network differs between…

Methodology · Statistics 2021-04-26 Byol Kim , Song Liu , Mladen Kolar