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Principal component analysis (PCA) is a popular dimension reduction technique often used to visualize high-dimensional data structures. In genomics, this can involve millions of variables, but only tens to hundreds of observations.…

Statistics Theory · Mathematics 2020-06-11 Kristoffer Hellton , Magne Thoresen

Principal component analysis (PCA) is a widely used dimension reduction tool in the analysis of many kind of high-dimensional data. It is used in signal processing, mechanical engineering, psychometrics, and other fields under different…

Methodology · Statistics 2014-01-15 Ngoc Mai Tran , Maria Osipenko , Wolfgang Karl Haerdle

In many longitudinal studies, a large number of variables are measured repeatedly over time, with substantial missing data. Existing methods, such as probabilistic principal component analysis (PPCA), are ill-equipped to handle such…

Methodology · Statistics 2026-04-27 Xinyu Zhang , Ameer Qaqish , D. Y. Lin , Didong Li

Intermittency analysis of factorial moments is a promising method used for the detection of power-law scaling in high-energy collision data. In particular, it has been employed in the search of fluctuations characteristic of the critical…

Data Analysis, Statistics and Probability · Physics 2025-07-03 Nikolaos Davis

The announcement in the summer of 2023 about the discovery of evidence for a gravitational wave background (GWB) using pulsar timing arrays (PTAs) has ignited both the PTA and the larger scientific community's interest in the experiment and…

Instrumentation and Methods for Astrophysics · Physics 2025-04-22 Nima Laal , Stephen R. Taylor , Rutger van Haasteren , William G Lamb , Xavier Siemens

Understanding disease progression at the molecular pathway level usually requires capturing both structural dependencies between pathways and the temporal dynamics of disease evolution. In this work, we solve the former challenge by…

Machine Learning · Computer Science 2025-02-11 Dai Shi , Kuan Yan , Lequan Lin , Yue Zeng , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

Big data applications, such as medical imaging and genetics, typically generate datasets that consist of few observations n on many more variables p, a scenario that we denote as p>>n. Traditional data processing methods are often…

Data Analysis, Statistics and Probability · Physics 2016-05-18 Magnus O. Ulfarsson , Frosti Palsson , Jakob Sigurdsson , Johannes R. Sveinsson

Survivors of childhood cancer need lifelong monitoring for side effects from radiotherapy. However, longitudinal data from routine monitoring is often infrequently and irregularly sampled, and subject to inaccuracies. Due to this,…

In recent years microbiome studies have become increasingly prevalent and large-scale. Through high-throughput sequencing technologies and well-established analytical pipelines, relative abundance data of operational taxonomic units and…

Methodology · Statistics 2022-05-12 Yan Li , Gen Li , Kun Chen

Difference-in-Differences (DID) research designs usually rely on variation of treatment timing such that, after making an appropriate parallel trends assumption, one can identify, estimate, and make inference about causal effects. In…

Econometrics · Economics 2020-09-07 Michelle Marcus , Pedro H. C. Sant'Anna

Principal Components Analysis is a widely used technique for dimension reduction and characterization of variability in multivariate populations. Our interest lies in studying when and why the rotation to principal components can be used…

Machine Learning · Statistics 2014-10-01 Daniel A Díaz-Pachón , Jean-Eudes Dazard , J. Sunil Rao

Data analysis often requires methods that are invariant with respect to specific transformations, such as rotations in case of images or shifts in case of images and time series. While principal component analysis (PCA) is a widely-used…

Machine Learning · Statistics 2024-01-30 Florian Heinrichs

Principal variables analysis (PVA) is a technique for selecting a subset of variables that capture as much of the information in a dataset as possible. Existing approaches for PVA are based on the Pearson correlation matrix, which is not…

Methodology · Statistics 2023-09-29 Dylan Clark-Boucher , Jeffrey W. Miller

Pulsar Timing Array (PTA) searches for nHz gravitational-wave backgrounds (GWBs) typically model time-correlated noise by assuming a diagonal covariance in Fourier space, neglecting inter-frequency correlations introduced by the finite…

Instrumentation and Methods for Astrophysics · Physics 2025-06-18 Marco Crisostomi , Rutger van Haasteren , Patrick M. Meyers , Michele Vallisneri

Gait recognition aims to distinguish different walking patterns by analyzing video-level human silhouettes, rather than relying on appearance information. Previous research on gait recognition has primarily focused on extracting local or…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Qian Wu , Ruixuan Xiao , Kaixin Xu , Jingcheng Ni , Boxun Li , Ziyao Xu

Principal Component Analysis (PCA) is a fundamental data preprocessing tool in the world of machine learning. While PCA is often thought of as a dimensionality reduction method, the purpose of PCA is actually two-fold: dimension reduction…

Machine Learning · Computer Science 2023-01-25 Arpita Gang , Waheed U. Bajwa

Often in Phase 3 clinical trials measuring a long-term time-to-event endpoint, such as overall survival or progression-free survival, investigators also collect repeated measures on biomarkers which may be predictive of the primary…

Methodology · Statistics 2022-11-30 Abigail J. Burdon , Lisa V. Hampson , Christopher Jennison

Principal component analysis (PCA) is commonly used in genetics to infer and visualize population structure and admixture between populations. PCA is often interpreted in a way similar to inferred admixture proportions, where it is assumed…

Methodology · Statistics 2023-02-10 Jan van Waaij , Song Li , Genís Garcia-Erill , Anders Albrechtsen , Carsten Wiuf

Principal component analysis (PCA) is largely adopted for chemical process monitoring and numerous PCA-based systems have been developed to solve various fault detection and diagnosis problems. Since PCA-based methods assume that the…

Machine Learning · Computer Science 2017-12-13 Haitao Zhao

Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal components are used to understand the variation in the data or to reduce the dimension of…