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Related papers: Modules in the metabolic network of E.coli with re…

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We present a new method of identifying a specific module in a dynamic network, possibly with feedback loops. Assuming known topology, we express the dynamics by an acyclic network composed of two blocks where the first block accounts for…

Systems and Control · Computer Science 2017-05-04 Niklas Everitt , Giulio Bottegal , Håkan Hjalmarsson

The functioning of a living cell is largely determined by the structure of its regulatory network, comprising non-linear interactions between regulatory genes. An important factor for the stability and evolvability of such regulatory…

Molecular Networks · Quantitative Biology 2015-05-13 Gunnar Boldhaus , Konstantin Klemm

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Recent studies have revealed that neural networks learn interpretable algorithms for many simple problems. However, little is known about how these algorithms emerge during training. In this article, I study the training dynamics of a small…

Machine Learning · Computer Science 2024-10-29 Tiberiu Musat

Modular verification is a technique used to face the state explosion problem often encountered in the verification of properties of complex systems such as concurrent interactive systems. The modular approach is based on the observation…

Logic in Computer Science · Computer Science 2012-11-20 Peter Drábik , Andrea Maggiolo-Schettini , Paolo Milazzo

Modularity structures are common in various social and biological networks. However, its dynamical origin remains an open question. In this work, we set up a dynamical model describing the evolution of a social network. Based on the…

Physics and Society · Physics 2011-08-19 Menghui Li , Shuguang Guan , Choy-Heng Lai

Aiming at improving the efficiency and accuracy of community detection in complex networks, we proposed a new algorithm, which is based on the idea that communities could be detected from subnetworks by comparing the internal and external…

Physics and Society · Physics 2016-12-20 Jihui Han , Wei Li , Weibing Deng

The galactose network is a complex system responsible for galactose metabolism. It has been extensively studied experimentally and mathematically at the unicellular level to broaden our understanding of its regulatory mechanisms at higher…

Molecular Networks · Quantitative Biology 2016-02-12 Tina M. Mitre , Anmar Khadra , Michael C. Mackey

Modularity is one of the most prominent properties of real-world complex networks. Here, we address the issue of module identification in two important classes of networks: bipartite networks and directed unipartite networks. Nodes in…

Data Analysis, Statistics and Probability · Physics 2011-11-10 R. Guimera , M. Sales-Pardo , L. A. N. Amaral

Mixtures of particles that interact through phoretic effects are known to aggregate if they belong to species that exhibit attractive self-interactions. We study self-organization in a model metabolic cycle composed of three species of…

Soft Condensed Matter · Physics 2023-09-29 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

The relationship between the design and functionality of molecular networks is now a key issue in biology. Comparison of regulatory networks performing similar tasks can give insights into how network architecture is constrained by the…

Molecular Networks · Quantitative Biology 2015-06-26 Ala Trusina , Kim Sneppen , Ian B. Dodd , Keith E. Shearwin , J. Barry Egan

The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the…

Neurons and Cognition · Quantitative Biology 2018-11-01 Gorka Zamora-López , Yuhan Chen , Gustavo Deco , Morten L. Kringelbach , Changsong Zhou

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

Neurons and Cognition · Quantitative Biology 2026-02-24 Alessandro Salatiello

The identification of cellular objectives is one of the central topics in the research of microbial metabolic networks. In particular, the information about a cellular objective is needed in flux balance analysis which is a commonly used…

Molecular Networks · Quantitative Biology 2012-03-22 Tommi Aho , Juha Kesseli , Olli Yli-Harja , Stuart A. Kauffman

The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…

Neurons and Cognition · Quantitative Biology 2014-03-26 Roberta Russo , Hans J Herrmann , Lucilla de Arcangelis

Unraveling the structure of complex biological networks and relating it to their functional role is an important task in systems biology. Here we attempt to characterize the functional organization of the large-scale metabolic networks of…

Molecular Networks · Quantitative Biology 2015-06-12 Shalini Singh , Areejit Samal , Varun Giri , Sandeep Krishna , Nandula Raghuram , Sanjay Jain

The connectome, or the entire connectivity of a neural system represented by network, ranges various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they…

Neurons and Cognition · Quantitative Biology 2014-10-01 Jinseop S. Kim , Marcus Kaiser

Escherichia coli and Bacillus subtilis are two of the best-studied prokaryotic model organisms. Previous analyses of their transcriptional regulatory networks have shown that they exhibit high plasticity during evolution and suggested that…

We consider the problem of detecting communities or modules in networks, groups of vertices with a higher-than-average density of edges connecting them. Previous work indicates that a robust approach to this problem is the maximization of…

Data Analysis, Statistics and Probability · Physics 2007-05-23 M. E. J. Newman

Identifying influential nodes in a network is a fundamental issue due to its wide applications, such as accelerating information diffusion or halting virus spreading. Many measures based on the network topology have emerged over the years…

Social and Information Networks · Computer Science 2022-12-26 Zakariya Ghalmane , Mohammed El Hassouni , Chantal Cherifi , Hocine Cherifi