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Disease-gene prediction (DGP) refers to the computational challenge of predicting associations between genes and diseases. Effective solutions to the DGP problem have the potential to accelerate the therapeutic development pipeline at early…
Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…
Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…
Graph convolutional network (GCN) is an emerging neural network approach. It learns new representation of a node by aggregating feature vectors of all neighbors in the aggregation process without considering whether the neighbors or…
Federated Collaborative Filtering (FedCF) is an emerging field focused on developing a new recommendation framework with preserving privacy in a federated setting. Existing FedCF methods typically combine distributed Collaborative Filtering…
Graph Neural Networks (GNNs) have shown excellent performance on graphs that exhibit strong homophily with respect to the node labels i.e. connected nodes have same labels. However, they perform poorly on heterophilic graphs. Recent…
To address the lack of public power system data for machine learning research in energy networks, we investigate the use of variational graph autoencoders (VGAEs) for synthetic distribution grid generation. Using two open-source datasets,…
Software-defined networking (SDN) and the network function virtualization (NFV) led to great developments in software based control technology by decreasing expenditures. Service function chaining (SFC) is an important technology to find…
Recently, Graph Convolutional Networks (GCNs) and their variants have been receiving many research interests for learning graph-related tasks. While the GCNs have been successfully applied to this problem, some caveats inherited from…
Recent advances in deep learning have accelerated its use in various applications, such as cellular image analysis and molecular discovery. In molecular discovery, a generative adversarial network (GAN), which comprises a discriminator to…
Learning representation for graph classification turns a variable-size graph into a fixed-size vector (or matrix). Such a representation works nicely with algebraic manipulations. Here we introduce a simple method to augment an attributed…
We introduce and analyze a general model of a population evolving over a network of selectively neutral genotypes. We show that the population's limit distribution on the neutral network is solely determined by the network topology and…
The mining and exploitation of graph structural information have been the focal points in the study of complex networks. Traditional structural measures in Network Science focus on the analysis and modelling of complex networks from the…
Several algorithms for RNA inverse folding have been used to design synthetic riboswitches, ribozymes and thermoswitches, whose activity has been experimentally validated. The RNAiFold software is unique among approaches for inverse folding…
Generative Adversarial Network (GAN) is a useful type of Neural Networks in various types of applications including generative models and feature extraction. Various types of GANs are being researched with different insights, resulting in a…
Neural networks for structured data like graphs have been studied extensively in recent years. To date, the bulk of research activity has focused mainly on static graphs. However, most real-world networks are dynamic since their topology…
Structural changes in a network representation of a system (e.g.,different experimental conditions, time evolution), can provide insight on its organization, function and on how it responds to external perturbations. The deeper…
Phylogenetic networks are used to represent evolutionary scenarios in biology and linguistics. To find the most probable scenario, it may be necessary to compare candidate networks, to distinguish different networks, and to see when one…
Understanding how genetic variants influence cellular-level processes is an important step towards understanding how they influence important organismal-level traits, or "phenotypes", including human disease susceptibility. To this end…
Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…