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In equilibrium self-assembly, microscopic building blocks spontaneously self-organize into stable structures as dictated by their interaction potentials, which limits the accessible structural features to those that correspond to global…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Chenghung Chou , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

Computational modeling of assembly is challenging for many systems because their timescales vastly exceed those accessible to simulations. This article describes the MultiMSM, which is a general framework that uses Markov state models…

Soft Condensed Matter · Physics 2024-05-07 Anthony Trubiano , Michael F. Hagan

We demonstrate that the assembly pathway method underlying assembly theory (AT) is an encoding scheme widely used by popular statistical compression algorithms. We show that in all cases (synthetic or natural) AT performs similarly to other…

Information Theory · Computer Science 2024-08-15 Abicumaran Uthamacumaran , Felipe S. Abrahão , Narsis A. Kiani , Hector Zenil

Assembly of protein complexes like virus shells, the centriole, the nuclear pore complex or the actin cytoskeleton is strongly determined by their spatial structure. Moreover it is becoming increasingly clear that the reversible nature of…

Subcellular Processes · Quantitative Biology 2014-05-13 Heinrich C. R. Klein , Ulrich S. Schwarz

This work unravels the atomic details of the interaction of solute atoms with nanoscale crystalline defects. The complexity of this phenomenon is elucidated through detailed atom probe tomographic investigations on epitaxially-strained,…

Materials Science · Physics 2021-12-22 Samik Mukherjee , Simone Assali , Oussama Moutanabbir

Inspired by recent successes using single-stranded DNA tiles to produce complex structures, we develop a two-step coarse-graining approach that uses detailed thermodynamic calculations with oxDNA, a nucleotide-based model of DNA, to…

Soft Condensed Matter · Physics 2018-04-09 Pedro Fonseca , Flavio Romano , John S. Schreck , Thomas E. Ouldridge , Jonathan P. K. Doye , Ard A. Louis

Self-assemblies, structured via nanoparticles, show promise as materials for advanced applications, like photonic devices, electrochemical energy storage units and catalysis support. Despite observing diverse morphologies, a comprehensive…

We present a theoretical description of a mechanism for self assembly in binary soft nanoparticle systems of the type which were studied experimentally by Talapin et al [1]. We focus on, in particular, the conditions for formation of…

Statistical Mechanics · Physics 2021-04-13 Anuradha Jagannathan

The self-assembly of anisotropic building blocks into complex spatial architectures is an important design strategy in material science but the mechanisms by which the anisotropic interactions influence the early-stage growth and formation…

Soft Condensed Matter · Physics 2026-05-05 Dillip Kumar Mohapatra , Teun W. J. Verouden , Janne-Mieke Meijer

Theories of protein crystallization based on spheres that form close-packed crystals predict optimal assembly within a `slot' of second virial coefficients and enhanced assembly near the metastable liquid-vapor critical point. However, most…

Soft Condensed Matter · Physics 2014-04-04 Thomas K. Haxton , Stephen Whitelam

At the nanometric scale, the synthesis of a random alloy (i.e. without phase segregation, whatever the composition) by chemical synthesis remains a not easy task, even for simple binary type systems. In this context, a unique approach based…

Aluminum alloys, the most widely utilized lightweight structural materials, predominantly depend on coherent complex-structured nano-plates to enhance their mechanical properties. Despite several decades of research, the atomic-scale…

Materials Science · Physics 2024-10-22 Junyuan Bai , Gaowu Qin , Xueyong Pang , Zhihao Zhao

We use numerical simulations to show how noninteracting hard particles binding to a deformable elastic shell may self-assemble into a variety of linear patterns. This is a result of the nontrivial elastic response to deformations of shells.…

Soft Condensed Matter · Physics 2011-02-25 Andela Šarić , Angelo Cacciuto

In this work we seek to understand some of the fundamental processes that govern self-assembly at the nanoscale in the context of the formation of metallic structures on patterned co-polymer templates. To this end we focus on the…

Materials Science · Physics 2007-05-23 Ajay Gopinathan

The self-assembly of binary nanoparticle superlattices from colloidal mixtures is a promising method for the fabrication of complex colloidal co-crystal structures. However, binary mixtures often form amorphous or metastable phases instead…

Soft Condensed Matter · Physics 2022-05-11 R. Allen LaCour , Timothy C. Moore , Sharon C. Glotzer

The cytoplasm is a heterogeneous mixture containing many types of proteins that self-assemble into a wide variety of complexes. The accuracy and speed of cytoplasmic self-assembly is astonishing because it involves the correct…

Statistical Mechanics · Physics 2025-11-21 Félix Benoist , Pablo Sartori

Protein assembly plays an important role throughout all phyla of life, both physiologically and pathologically. In particular, aggregation and polymerization of proteins are key-strategies that regulate cellular function. In recent years,…

I present a review of the theoretical and computational methodologies that have been used to model the assembly of viral capsids. I discuss the capabilities and limitations of approaches ranging from equilibrium continuum theories to…

Biomolecules · Quantitative Biology 2013-01-09 Michael F. Hagan

With their ability to handle an increased amount of information, multivariate and multichannel signals can be used to solve problems normally not solvable with signals obtained from a single source. One such problem is the decomposition…

Information Theory · Computer Science 2019-04-02 Ljubisa Stankovic , Milos Brajovic , Milos Dakovic , Danilo Mandic

Interactions between the components in many-body systems can give rise to spontaneous formation of complex structures. Usually very little is known about the connection between the interactions and the resulting structure. Here we present a…

Soft Condensed Matter · Physics 2014-05-16 Erik Edlund , Oskar Lindgren , Martin Nilsson Jacobi