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Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

This thesis establishes a generalised setting with which to unify the study of finite local complexity (FLC) patterns. The abstract notion of a "pattern" is introduced, which may be seen as an analogue of the space group of isometries…

General Topology · Mathematics 2014-05-26 James J. Walton

Given an unknown $\mathbb{R}^n$-valued function $f$ on a metric space $X$, can we approximate the persistent homology of $f$ from a finite sampling of $X$ with known pairwise distances and function values? This question has been answered in…

Algebraic Topology · Mathematics 2026-03-20 Ethan André , Jingyi Li , David Loiseaux , Steve Oudot

We analyze in this paper a random feature map based on a theory of invariance I-theory introduced recently. More specifically, a group invariant signal signature is obtained through cumulative distributions of group transformed random…

Machine Learning · Computer Science 2015-12-07 Youssef Mroueh , Stephen Voinea , Tomaso Poggio

What is the "right" topological invariant of a large point cloud X? Prior research has focused on estimating the full persistence diagram of X, a quantity that is very expensive to compute, unstable to outliers, and far from a sufficient…

Algebraic Topology · Mathematics 2022-02-18 Elchanan Solomon , Alexander Wagner , Paul Bendich

Spinorial methods have proven to be a powerful tool to study geometric properties of spin manifolds. Our aim is to continue the spinorial study of manifolds that are not necessarily spin. We introduce and study the notion of $G$-invariance…

Differential Geometry · Mathematics 2025-09-15 Diego Artacho , Marie-Amélie Lawn

Recently, there has been an emerging trend to integrate persistent homology (PH) into graph neural networks (GNNs) to enrich expressive power. However, naively plugging PH features into GNN layers always results in marginal improvement with…

Machine Learning · Computer Science 2024-10-21 Chaolong Ying , Xinjian Zhao , Tianshu Yu

Biological and physical systems often exhibit distinct structures at different spatial/temporal scales. Persistent homology is an algebraic tool that provides a mathematical framework for analyzing the multi-scale structures frequently…

Algebraic Topology · Mathematics 2016-02-01 Jonathan Jaquette , Miroslav Kramár

Persistent topological properties of an image serve as an additional descriptor providing an insight that might not be discovered by traditional neural networks. The existing research in this area focuses primarily on efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Ekaterina Khramtsova , Guido Zuccon , Xi Wang , Mahsa Baktashmotlagh

A number of machine learning tasks entail a high degree of invariance: the data distribution does not change if we act on the data with a certain group of transformations. For instance, labels of images are invariant under translations of…

Machine Learning · Statistics 2021-03-01 Song Mei , Theodor Misiakiewicz , Andrea Montanari

Persistent Homology (PH) is a useful tool to study the underlying structure of a data set. Persistence Diagrams (PDs), which are 2D multisets of points, are a concise summary of the information found by studying the PH of a data set.…

Computational Geometry · Computer Science 2020-11-24 Megan Johnson , Jae-Hun Jung

The existence of characteristic structure, or shape, in complex data sets has been recognized as increasingly important for mathematical data analysis. This realization has motivated the development of new tools such as persistent homology…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Sofya Chepushtanova , Michael Kirby , Chris Peterson , Lori Ziegelmeier

This article has two goals. First, we hope to give an accessible introduction to persistent equivariant cohomology. Given a topological group $G$ acting on a filtered space, persistent Borel equivariant cohomology measures not only the…

Algebraic Topology · Mathematics 2024-09-02 Henry Adams , Evgeniya Lagoda , Michael Moy , Nikola Sadovek , Aditya De Saha

We develop the theoretical foundations of a generalized Gromov-Hausdorff distance between functions on networks that has recently been applied to various subfields of topological data analysis and optimal transport. These functional…

Discrete Mathematics · Computer Science 2022-12-08 Samir Chowdhury , Facundo Mémoli

Inferring topological and geometrical information from data can offer an alternative perspective on machine learning problems. Methods from topological data analysis, e.g., persistent homology, enable us to obtain such information,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Christoph Hofer , Roland Kwitt , Marc Niethammer , Andreas Uhl

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

A large driver of the complexity of graph learning is the interplay between structure and features. When analyzing the expressivity of graph neural networks, however, existing approaches ignore features in favor of structure, making it…

Machine Learning · Computer Science 2026-03-04 Martin Carrasco , Olga Zaghen , Kavir Sumaraj , Erik Bekkers , Bastian Rieck

Persistent homology is a powerful mathematical tool that summarizes useful information about the shape of data allowing one to detect persistent topological features while one adjusts the resolution. However, the computation of such…

Quantum Physics · Physics 2022-03-01 Bernardo Ameneyro , Vasileios Maroulas , George Siopsis

Persistent homology (PH) has been widely applied to graph data to extract topological features. However, little attention has been paid to how different distance functions on a graph affect the resulting persistence barcodes and their…

Algebraic Topology · Mathematics 2026-02-17 Eunwoo Heo , Byeongchan Choi , Jae-Hun Jung

Persistent homology is constrained to purely topological persistence while multiscale graphs account only for geometric information. This work introduces persistent spectral theory to create a unified low-dimensional multiscale paradigm for…

Combinatorics · Mathematics 2019-12-13 Rui Wang , Duc Duy Nguyen , Guo-Wei Wei
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