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The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics…
In the 21st century, biosensors have gathered much wider attention than ever before, irrespective of the technology that promises to bring them forward. With the recent COVID-19 outbreak, the concern and efforts to restore global health and…
We study the problem of estimating the origin of an epidemic outbreak -- given a contact network and a snapshot of epidemic spread at a certain time, determine the infection source. Finding the source is important in different contexts of…
This study presents a novel approach at the intersection of genomic analysis and artificial intelligence (AI) to predict viral mutations and assess the risks of future pandemics. Through comprehensive genomic analysis, genetic markers…
Linear waste management systems are unsustainable and contribute to environmental degradation, economic inequity, and health disparities. Among the array of environmental challenges stemming from anthropogenic impacts, the management of…
Understanding how epidemics spread in a system is a crucial step to prevent and control outbreaks, with broad implications on the system's functioning, health, and associated costs. This can be achieved by identifying the elements at higher…
Organisms have evolved immune systems that can counter pathogenic threats. The adaptive immune system in vertebrates consists of a diverse repertoire of immune receptors that can dynamically reorganize to specifically target the…
Zoonosis refers to the transmission of infectious diseases from animal to human. The increasing number of zoonosis incidence makes the great losses to lives, including humans and animals, and also the impact in social economic. It motivates…
Estimating population-level prevalence and transmission dynamics of wildlife pathogens can be challenging, partly because surveillance data is sparse, detection-driven, and unevenly sequenced. Using highly pathogenic avian influenza A/H5…
Corporate responses to illness is currently an ad-hoc, subjective process that has little basis in data on how disease actually spreads at the workplace. Additionally, many studies have shown that productivity is not an individual factor…
Feeding the growing human population sustainably amidst climate change is one of the most important challenges in the 21st century. Current practices often lead to the overuse of agronomic inputs, such as synthetic fertilizers and water,…
ZV-Sim is an open-source, modular Python framework for probabilistic simulation and analysis of pre-emergent novel zoonotic diseases using pervasive sensing data. It incorporates customizable Human and Animal Presence agents that leverage…
Biodefense is the discipline of ensuring biosecurity with respect to select groups of organisms and limiting their spread. This field has increasingly been challenged by novel threats from nature that have been weaponized such as SARS,…
Causality and causal inference have emerged as core research areas at the interface of modern statistics and domains including biomedical sciences, social sciences, computer science, and beyond. The field's inherently interdisciplinary…
The human-associated microbiome is closely tied to human health and is of substantial clinical interest. Metagenomics-based tools are emerging for clinical diagnostics, tracking the spread of diseases, and surveillance of potential…
This paper introduces an innovative model for infectious diseases in predator-prey populations. We not only prove the existence of global non-negative solutions but also establish essential criteria for the system's decline and…
Diagnostic tests that can detect pre-clinical or sub-clinical infection, are one of the most powerful tools in our armoury of weapons to control infectious diseases. Considerable effort has been paid to improving diagnostic testing for…
Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…
From pathogens and computer viruses to genes and memes, contagion models have found widespread utility across the natural and social sciences. Despite their success and breadth of adoption, the approach and structure of these models remain…
Biocybersecurity is a novel space for the 21st century that meets our innovations in biotechnology and computing head on. Within this space, many considerations are open for and demand consideration as groups endeavor to develop products…