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The Moran process models the spread of genetic mutations through a population. A mutant with relative fitness $r$ is introduced into a population and the system evolves, either reaching fixation (in which every individual is a mutant) or…

Computational Engineering, Finance, and Science · Computer Science 2013-08-01 Josep Diaz , Leslie Ann Goldberg , George B. Mertzios , David Richerby , Maria Serna , Paul G. Spirakis

The fixation probability of a single mutant invading a population of residents is among the most widely-studied quantities in evolutionary dynamics. Amplifiers of natural selection are population structures that increase the fixation…

Populations and Evolution · Quantitative Biology 2020-07-01 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

We consider the classic Moran process modeling the spread of genetic mutations, as extended to structured populations by Lieberman et al.\ (Nature, 2005). In this process, individuals are the vertices of a connected graph $G$. Initially,…

Discrete Mathematics · Computer Science 2016-11-08 George Giakkoupis

We consider the Moran process in a graph called the "star" and obtain the asymptotic expression for the fixation probability of a single mutant when the size of the graph is large. The expression obtained corrects the previously known…

Populations and Evolution · Quantitative Biology 2016-03-21 Fabio A. C. C. Chalub

Populations evolve by accumulating advantageous mutations. Every population has some spatial structure that can be modeled by an underlying network. The network then influences the probability that new advantageous mutations fixate.…

Populations and Evolution · Quantitative Biology 2024-01-29 Jakub Svoboda , Soham Joshi , Josef Tkadlec , Krishnendu Chatterjee

We consider the modified Moran process on graphs to study the spread of genetic and cultural mutations on structured populations. An initial mutant arises either spontaneously (aka \emph{uniform initialization}), or during reproduction (aka…

Discrete Mathematics · Computer Science 2018-05-15 Andreas Pavlogiannis , Josef Tkadlec , Krishnendu Chatterjee , Martin A. Nowak

Evolutionary dynamics on graphs can lead to many interesting and counterintuitive findings. We study the Moran process, a discrete time birth-death process, that describes the invasion of a mutant type into a population of wild-type…

Populations and Evolution · Quantitative Biology 2015-04-23 Laura Hindersin , Arne Traulsen

The rate of biological evolution depends on the fixation probability and on the fixation time of new mutants. Intensive research has focused on identifying population structures that augment the fixation probability of advantageous mutants.…

Populations and Evolution · Quantitative Biology 2019-03-11 Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

This work studies the generalized Moran process, as introduced by Lieberman et al. [Nature, 433:312-316, 2005]. We introduce the parameterized notions of selective amplifiers and selective suppressors of evolution, i.e. of networks (graphs)…

Data Structures and Algorithms · Computer Science 2018-05-02 George B. Mertzios , Paul G. Spirakis

The spatial structure of an evolving population affects which mutations become fixed. Some structures amplify selection, increasing the likelihood that beneficial mutations become fixed while deleterious mutations do not. Other structures…

The Moran process, as studied by Lieberman, Hauert and Nowak, is a randomised algorithm modelling the spread of genetic mutations in populations. The algorithm runs on an underlying graph where individuals correspond to vertices. Initially,…

Probability · Mathematics 2016-05-06 Andreas Galanis , Andreas Göbel , Leslie Ann Goldberg , John Lapinskas , David Richerby

We consider a generalized version of the birth-death (BD) and death-birth (DB) processes introduced by Kaveh, Komarova, and Kohandel (2015), in which two constant fitnesses, one for birth and the other for death, describe the selection…

Probability · Mathematics 2025-12-08 Poly H. da Silva , Max O. Souza

This paper is based on the complete classification of evolutionary scenarios for the Moran process with two strategies given by Taylor et al. (B. Math. Biol. 66(6): 1621--1644, 2004). Their classification is based on whether each strategy…

Populations and Evolution · Quantitative Biology 2018-11-27 Evandro P. Souza , Eliza M. Ferreira , Armando G. M. Neves

Evolutionary games on graphs describe how strategic interactions and population structure determine evolutionary success, quantified by the probability that a single mutant takes over a population. Graph structures, compared to the…

Populations and Evolution · Quantitative Biology 2017-05-08 Philipp M. Altrock , Arne Traulsen , Martin A. Nowak

Natural microbial populations often have complex spatial structures. This can impact their evolution, in particular the ability of mutants to take over. While mutant fixation probabilities are known to be unaffected by sufficiently…

Populations and Evolution · Quantitative Biology 2024-12-30 Alia Abbara , Anne-Florence Bitbol

We analyze evolutionary dynamics on graphs, where the nodes represent individuals of a population. The links of a node describe which other individuals can be displaced by the offspring of the individual on that node. Amplifiers of…

Populations and Evolution · Quantitative Biology 2016-10-27 Laura Hindersin , Arne Traulsen

Hypergraphs have been a useful tool for analyzing population dynamics such as opinion formation and the public goods game occurring in overlapping groups of individuals. In the present study, we propose and analyze evolutionary dynamics on…

Physics and Society · Physics 2023-10-16 Ruodan Liu , Naoki Masuda

Inspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present the first known examples of undirected structures acting as suppressors of selection for any fitness…

Populations and Evolution · Quantitative Biology 2017-11-01 Fernando Alcalde Cuesta , Pablo González Sequeiros , Álvaro Lozano Rojo

Different evolutionary models are known to make disparate predictions for the success of an invading mutant in some situations. For example, some evolutionary mechanics lead to amplification of selection in structured populations, while…

Populations and Evolution · Quantitative Biology 2020-07-01 Francisco Herrerías-Azcué , Vicente Pérez-Muñuzuri , Tobias Galla

In evolutionary dynamics, a key measure of a mutant trait's success is the probability that it takes over the population given some initial mutant-appearance distribution. This "fixation probability" is difficult to compute in general, as…

Populations and Evolution · Quantitative Biology 2022-02-18 Alex McAvoy , Benjamin Allen
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