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Previous studies on event-related functional magnetic resonance imaging experimental designs are primarily based on linear models, in which a known shape of the hemodynamic response function (HRF) is assumed. However, the HRF shape is…

Applications · Statistics 2014-01-09 Ming-Hung Kao , Dibyen Majumdar , Abhyuday Mandal , John Stufken

Extracting activation patterns from functional Magnetic Resonance Images (fMRI) datasets remains challenging in rapid-event designs due to the inherent delay of blood oxygen level-dependent (BOLD) signal. The general linear model (GLM)…

Machine Learning · Computer Science 2013-05-14 Fabian Pedregosa , Michael Eickenberg , Bertrand Thirion , Alexandre Gramfort

Functional Magnetic Resonance Imaging is a noninvasive tool for studying cerebral function. Many factors challenge activation detection, especially in low-signal scenarios that arise in the performance of high-level cognitive tasks. We…

Methodology · Statistics 2019-05-07 Israel Almodóvar-Rivera , Ranjan Maitra

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

Statistics Theory · Mathematics 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Functional Magnetic Resonance Imaging (fMRI) relies on multi-step data processing pipelines to accurately determine brain activity; among them, the crucial step of spatial smoothing. These pipelines are commonly suboptimal, given the local…

Computer Vision and Pattern Recognition · Computer Science 2017-10-03 Albert Vilamala , Kristoffer Hougaard Madsen , Lars Kai Hansen

When working with task-related fMRI data, one of the most crucial parts of the data analysis consists of determining a proper estimate of the BOLD response. The following document presents a lite model for the Hemodynamic Response Function…

Neurons and Cognition · Quantitative Biology 2020-04-29 Manuel Morante

In this paper we introduce a new hierarchical model for the simultaneous detection of brain activation and estimation of the shape of the hemodynamic response in multi-subject fMRI studies. The proposed approach circumvents a major…

Applications · Statistics 2015-11-13 David Degras , Martin A. Lindquist

As the deep learning revolution marches on, masked modeling has emerged as a distinctive approach that involves predicting parts of the original data that are proportionally masked during training, and has demonstrated exceptional…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Qinrong Cai , Yu Guan , Zhibo Chen , Dong Liang , Qiuyun Fan , Qiegen Liu

Neuronal brain activity in response to repeated stimuli can be perceived using functional magnetic resonance imaging (fMRI). In this paper, we develop a statistical model for fMRI data that estimates both the associated haemodynamic…

Applications · Statistics 2015-01-26 Christopher J. Brignell , William J. Browne , Ian L. Dryden , Susan T. Francis

Computational studies that use block-structured adaptive mesh refinement (AMR) approaches suffer from unnecessarily high mesh resolution in regions adjacent to important solution features. This deficiency limits the performance of AMR…

Computational Physics · Physics 2022-03-02 Brandon Gusto , Tomasz Plewa

Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 William Consagra , Eardi Lila

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

Methodology · Statistics 2023-10-30 Fangyijie Wang , Michael Salter-Townshend

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

Scaling temporal dynamics in functional MRI (fMRI) signals have been evidenced for a decade as intrinsic characteristics of ongoing brain activity (Zarahn et al., 1997). Recently, scaling properties were shown to fluctuate across brain…

Statistics Theory · Mathematics 2013-08-21 P. Ciuciu , G. Varoquaux , P. Abry , S. Sadaghiani , A. Kleinschmidt

Accurate fMRI analysis requires sensitivity to temporal structure across multiple scales, as BOLD signals encode cognitive processes that emerge from fast transient dynamics to slower, large-scale fluctuations. Existing deep learning (DL)…

Signal Processing · Electrical Eng. & Systems 2026-01-06 Furkan Genç , Boran İsmet Macun , Sait Sarper Özaslan , Emine U. Saritas , Tolga Çukur

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

The hemodynamic response (HR) in event-related functional magnetic resonance imaging is typically assumed to be stationary. While there are some approaches in the literature to model nonstationary HRs, few focus on rapid changes. In this…

Methodology · Statistics 2025-02-19 Friederike Preusse , Thorsten Dickhaus , André Brechmann

Functional Magnetic Resonance Imaging (fMRI) data is a widely used kind of four-dimensional biomedical data, which requires effective compression. However, fMRI compressing poses unique challenges due to its intricate temporal dynamics, low…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ruoran Li , Runzhao Yang , Wenxin Xiang , Yuxiao Cheng , Tingxiong Xiao , Jinli Suo

Standard detection of evoked brain activity in functional MRI (fMRI) relies on a fixed and known shape of the impulse response of the neurovascular coupling, namely the hemodynamic response function (HRF). To cope with this issue, the joint…

Applications · Statistics 2015-01-07 Aina Frau-Pascual , Thomas Vincent , Florence Forbes , Philippe Ciuciu
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