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Motivation: Cellular Electron CryoTomography (CECT) is an emerging 3D imaging technique that visualizes subcellular organization of single cells at submolecular resolution and in near-native state. CECT captures large numbers of…

Quantitative Methods · Quantitative Biology 2018-05-16 Yixiu Zhao , Xiangrui Zeng , Qiang Guo , Min Xu

Factorized information criterion (FIC) is a recently developed approximation technique for the marginal log-likelihood, which provides an automatic model selection framework for a few latent variable models (LVMs) with tractable inference…

Machine Learning · Computer Science 2015-04-23 Kohei Hayashi , Shin-ichi Maeda , Ryohei Fujimaki

We present a computational motivation for restricted maximum likelihood (REML) estimation in linear mixed models using an expectation--maximization (EM) algorithm. At each iteration, maximum likelihood (ML) and REML solve the same…

Computation · Statistics 2026-02-11 Andrew T. Karl

The EM-algorithm is a general procedure to get maximum likelihood estimates if part of the observations on the variables of a network are missing. In this paper a stochastic version of the algorithm is adapted to probabilistic neural…

Artificial Intelligence · Computer Science 2013-03-26 Gerhard Paass

Handling missing values plays an important role in the analysis of survival data, especially, the ones marked by cure fraction. In this paper, we discuss the properties and implementation of stochastic approximations to the…

Methodology · Statistics 2021-07-22 Sandip Barui , Suvra Pal , Nutan Mishra , Katherine Davies

This paper proposes a new approach for Bayesian and maximum likelihood parameter estimation for stationary Gaussian processes observed on a large lattice with missing values. We propose an MCMC approach for Bayesian inference, and a Monte…

Computation · Statistics 2014-02-19 Jonathan R. Stroud , Michael L. Stein , Shaun Lysen

Targeted Maximum Likelihood Estimation (TMLE) is increasingly used for doubly robust causal inference, but how missing data should be handled when using TMLE with data-adaptive approaches is unclear. Based on the Victorian Adolescent Health…

In some multivariate problems with missing data, pairs of variables exist that are never observed together. For example, some modern biological tools can produce data of this form. As a result of this structure, the covariance matrix is…

Methodology · Statistics 2013-08-13 Max Grazier G'Sell , Shai S. Shen-Orr , Robert Tibshirani

For many machine learning tasks, the input data lie on a low-dimensional manifold embedded in a high dimensional space and, because of this high-dimensional structure, most algorithms are inefficient. The typical solution is to reduce the…

Machine Learning · Computer Science 2019-03-05 Anna C. Gilbert , Rishi Sonthalia

Stochastic Maximum Likelihood (SML) is a popular direction of arrival (DOA) estimation technique in array signal processing. It is a parametric method that jointly estimates signal and instrument noise by maximum likelihood, achieving…

Applications · Statistics 2021-02-04 Matthieu Simeoni , Paul Hurley

Estimating the Individual Treatment Effect from observational data, defined as the difference between outcomes with and without treatment or intervention, while observing just one of both, is a challenging problems in causal learning. In…

Machine Learning · Computer Science 2020-05-07 Céline Beji , Michaël Bon , Florian Yger , Jamal Atif

Model error covariances play a central role in the performance of data assimilation methods applied to nonlinear state-space models. However, these covariances are largely unknown in most of the applications. A misspecification of the model…

Computation · Statistics 2019-11-06 María Magdalena Lucini , Peter Jan van Leeuwen , Manuel Pulido

The expectation-maximization (EM) algorithm and its variants are widely used in statistics. In high-dimensional mixture linear regression, the model is assumed to be a finite mixture of linear regression and the number of predictors is much…

Statistics Theory · Mathematics 2023-07-24 Ning Wang , Xin Zhang , Qing Mai

Over the past decades, there has been a surge of interest in studying low-dimensional structures within high-dimensional data. Statistical factor models $-$ i.e., low-rank plus diagonal covariance structures $-$ offer a powerful framework…

Machine Learning · Statistics 2025-05-20 Daniel Cederberg

We propose an l1-regularized likelihood method for estimating the inverse covariance matrix in the high-dimensional multivariate normal model in presence of missing data. Our method is based on the assumption that the data are missing at…

Methodology · Statistics 2012-02-28 Nicolas Städler , Peter Bühlmann

We consider an empirical likelihood inference for parameters defined by general estimating equations when some components of the random observations are subject to missingness. As the nature of the estimating equations is wide-ranging, we…

Statistics Theory · Mathematics 2009-03-05 Dong Wang , Song Xi Chen

In this paper, we present a method of maximum a posteriori estimation of parameters in dynamic factor models with incomplete data. We extend maximum likelihood expectation maximization iterations by Ba\'nbura & Modugno (2014) to penalized…

Methodology · Statistics 2022-10-14 Erik Spånberg

Many datasets suffer from missing values due to various reasons,which not only increases the processing difficulty of related tasks but also reduces the accuracy of classification. To address this problem, the mainstream approach is to use…

Machine Learning · Computer Science 2024-08-14 Cong Guo , Chun Liu , Wei Yang

Equalisation Maximisation (EqM) is an algorithm for estimating parameters in auto-regressive (AR) models where some fraction of the data is missing. It has previously been shown that the EqM algorithm is a competitive alternative to…

Computation · Statistics 2013-08-22 Johan Dahlin , Fredrik Lindsten , Thomas B. Schön

Predictive values are measures of the clinical accuracy of a binary diagnostic test, and depend on the sensitivity and the specificity of the test and on the disease prevalence among the population being studied. This article studies…

Other Statistics · Statistics 2024-08-14 Jose Antonio Roldan-Nofuentes
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