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Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the…

Quantitative Methods · Quantitative Biology 2023-04-26 Soumya Das , D. Vijay Anand , Moo K. Chung

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

Applications · Statistics 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

The importance of studying the brain microstructure is described and the existing and state of the art non-invasive methods for the investigation of the brain microstructure using Diffusion Weighted Magnetic Resonance Imaging (DWI) is…

Neural and Evolutionary Computing · Computer Science 2013-11-13 Hamed Yousefi Mesri

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

Neural and Evolutionary Computing · Computer Science 2014-07-16 Axel Wismüller , Xixi Wang , Adora M. DSouza , Mahesh B. Nagarajan

In statistical connectomics, the quantitative study of brain networks, estimating the mean of a population of graphs based on a sample is a core problem. Often, this problem is especially difficult because the sample or cohort size is…

Tractography has become an indispensable part of brain connectivity studies. However, it is currently facing problems with reliability. In particular, a substantial amount of nerve fiber reconstructions (streamlines) in tractograms produced…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Antonia Hain , Daniel Jörgens , Rodrigo Moreno

Resting-state functional magnetic resonance imaging (rsfMRI) is a powerful tool for investigating the relationship between brain function and cognitive processes as it allows for the functional organization of the brain to be captured…

Machine Learning · Computer Science 2025-02-25 Bishal Thapaliya , Esra Akbas , Jiayu Chen , Raam Sapkota , Bhaskar Ray , Pranav Suresh , Vince Calhoun , Jingyu Liu

We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…

Medical Physics · Physics 2025-09-19 Yoshiki Kubota , Yosuke Nagata , Manabu Tamura , Akimasa Hirata

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Due to imaging artifacts and low signal-to-noise ratio in ultrasound images, automatic bone surface segmentation networks often produce fragmented predictions that can hinder the success of ultrasound-guided computer-assisted surgical…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Aimon Rahman , Wele Gedara Chaminda Bandara , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Graphical models have been used extensively for modeling brain connectivity networks. However, unmeasured confounders and correlations among measurements are often overlooked during model fitting, which may lead to spurious scientific…

Methodology · Statistics 2020-12-10 Yanxin Jin , Yang Ning , Kean Ming Tan

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

In this paper, we use data from the Human Connectome Project (N=461) to investigate the effect of scan length on reliability of resting-state functional connectivity (rsFC) estimates produced from resting-state functional magnetic resonance…

Applications · Statistics 2016-06-22 Amanda F. Mejia , Mary Beth Nebel , Anita D. Barber , Ann S. Choe , Martin A. Lindquist

Conventional visualization media such as MRI prints and computer screens are inherently two dimensional, making them incapable of displaying true 3D volume data sets. By applying only transparency or intensity projection, and ignoring…

Graphics · Computer Science 2007-05-23 Gibby Koldenhof

Human brain activity is often measured using the blood-oxygen-level dependent (BOLD) signals obtained through functional magnetic resonance imaging (fMRI). The strength of connectivity between brain regions is then measured as a Pearson…

Other Quantitative Biology · Quantitative Biology 2022-05-20 Moo K. Chung , Zijian Chen

When re-structuring patient cohorts into so-called population graphs, initially independent data points can be incorporated into one interconnected graph structure. This population graph can then be used for medical downstream tasks using…

Social and Information Networks · Computer Science 2023-09-20 Tamara T. Mueller , Sophie Starck , Leonhard F. Feiner , Kyriaki-Margarita Bintsi , Daniel Rueckert , Georgios Kaissis

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland
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