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Scaling long-context capabilities is crucial for Multimodal Large Language Models (MLLMs). However, real-world multimodal datasets are extremely heterogeneous. Existing training frameworks predominantly rely on static parallelism…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-26 Yifan Niu , Han Xiao , Dongyi Liu , Wei Zhou , Jia Li

As the artificial intelligence community advances into the era of large models with billions of parameters, distributed training and inference have become essential. While various parallelism strategies-data, model, sequence, and…

Machine Learning · Computer Science 2025-03-13 Ruifeng She , Bowen Pang , Kai Li , Zehua Liu , Tao Zhong

Medical vision language pre-training (VLP) has emerged as a frontier of research, enabling zero-shot pathological recognition by comparing the query image with the textual descriptions for each disease. Due to the complex semantics of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Vu Minh Hieu Phan , Yutong Xie , Yuankai Qi , Lingqiao Liu , Liyang Liu , Bowen Zhang , Zhibin Liao , Qi Wu , Minh-Son To , Johan W. Verjans

The machine learning (ML) and deep learning (DL) techniques are widely recognized to be powerful tools for virtual drug screening. The recently reported ML- or DL-based scoring functions have shown exciting performance in predicting…

Quantitative Methods · Quantitative Biology 2023-07-07 Zechen Wang , Liangzhen Zheng , Sheng Wang , Mingzhi Lin , Zhihao Wang , Adams Wai-Kin Kong , Yuguang Mu , Yanjie Wei , Weifeng Li

Virtual Screening (VS) of vast compound libraries guided by Artificial Intelligence (AI) models is a highly productive approach to early drug discovery. Data splitting is crucial for better benchmarking of such AI models. Traditional random…

Quantitative Methods · Quantitative Biology 2024-07-02 Qianrong Guo , Saiveth Hernandez-Hernandez , Pedro J Ballester

Document parsing, as a fundamental yet crucial vision task, is being revolutionized by vision-language models (VLMs). However, the autoregressive (AR) decoding inherent to VLMs creates a significant bottleneck, severely limiting parsing…

Computation and Language · Computer Science 2026-03-17 Lei Li , Ze Zhao , Meng Li , Zhongwang Lun , Yi Yuan , Xingjing Lu , Zheng Wei , Jiang Bian , Zang Li

Digital pathology has fundamentally altered diagnostic workflows by enabling the computational analysis of gigapixel Whole Slide Images (WSIs), yet effectively deciphering their complex tumor microenvironments remains a formidable…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuemei Qiu , Dawei Fan , Yebin Huang , Yanping Chen , Lifang Wei

High-Performance Computing (HPC) platforms enable scientific software to achieve breakthroughs in many research fields such as physics, biology, and chemistry, by employing Research Software Engineering (RSE) techniques. These include 1)…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-16 Matan Rusanovsky , Re'em Harel , Lee-or Alon , Idan Mosseri , Harel Levin , Gal Oren

A new generation of manycore processors is on the rise that offers dozens and more cores on a chip and, in a sense, fuses host processor and accelerator. In this paper we target the efficient training of generalized linear models on these…

Performance · Computer Science 2021-10-29 Eliza Wszola , Celestine Mendler-Dünner , Martin Jaggi , Markus Püschel

Large-scale HPC simulations of plasma dynamics in fusion devices require efficient parallel I/O to avoid slowing down the simulation and to enable the post-processing of critical information. Such complex simulations lacking parallel I/O…

Cross-core communication is increasingly a bottleneck as the number of processing elements increase per system-on-chip. Typical hardware solutions to cross-core communication are often inflexible; while software solutions are flexible, they…

Hardware Architecture · Computer Science 2021-01-21 Qinzhe Wu , Jonathan Beard , Ashen Ekanayake , Andreas Gerstlauer , Lizy K. John

This study proposes a deep learning-based approach for discovering loops in programming code according to their potential for parallelization. Two genetic algorithm-based code generators were developed to produce two distinct types of code:…

Machine Learning · Computer Science 2025-10-03 Izavan dos S. Correia , Henrique C. T. Santos , Tiago A. E. Ferreira

Self-driving laboratories offer a promising path toward reducing the labor-intensive, time-consuming, and often irreproducible workflows in the biological sciences. Yet their stringent precision requirements demand highly robust models…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Anbang Liu , Guanzhong Hu , Jiayi Wang , Ping Guo , Han Liu

For image-related deep learning tasks, the first step often involves reading data from external storage and performing preprocessing on the CPU. As accelerator speed increases and the number of single compute node accelerators increases,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-30 Jia Wei , Xingjun Zhang , Witold Pedrycz , Longxiang Wang , Jie Zhao

Molecular docking is an essential step in the drug discovery process involving the detection of three-dimensional poses of a ligand inside the active site of the protein. In this paper, we address the Molecular Docking search phase by…

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Scientific applications are often complex, irregular, and computationally-intensive. To accommodate the ever-increasing computational demands of scientific applications, high-performance computing (HPC) systems have become larger and more…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-20 Ali Mohammed , Aurelien Cavelan , Florina M. Ciorba , Ruben M. Cabezon , Ioana Banicesu

Speculative decoding accelerates large language model inference by using smaller draft models to generate candidate tokens for parallel verification. However, current approaches are limited by sequential stage dependencies that prevent full…

Artificial Intelligence · Computer Science 2025-05-06 Bradley McDanel , Sai Qian Zhang , Yunhai Hu , Zining Liu

High-level synthesis (HLS) aims at democratizing custom hardware acceleration with highly abstracted software-like descriptions. However, efficient accelerators still require substantial low-level hardware optimizations, defeating the HLS…

Hardware Architecture · Computer Science 2024-11-21 Giovanni Brignone , Roberto Bosio , Fabrizio Ottati , Claudio Sansoè , Luciano Lavagno

Understanding and extracting structured insights from unstructured documents remains a foundational challenge in industrial NLP. While Large Language Models (LLMs) enable zero-shot extraction, traditional pipelines often fail to handle…