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This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

An algorithm based on PLS regression has been developed and optimized for measuring blood glucose level using the infra-red transmission spectrum of blood samples. A set of blood samples were tagged with their glucose concentration using an…

Quantitative Methods · Quantitative Biology 2018-04-11 Afarin Aghassizadeh , Mohammad Reza Nematollahi , Iman Mirzaie , Mehdi Fardmanesh

Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's…

Machine Learning · Computer Science 2020-03-23 Rafael T. Sousa , Lucas A. Pereira , Anderson S. Soares

People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring…

Signal Processing · Electrical Eng. & Systems 2020-09-08 Taiyu Zhu , Kezhi Li , Pau Herrero , Pantelis Georgiou

Chronic diseases such as diabetes are quite prevalent in the world and are responsible for a significant number of deaths per year. In addition, treatments for such chronic diseases account for a high healthcare cost. However, research has…

Machine Learning · Computer Science 2021-09-07 Asish Satpathy , Satyajit Behari

To perform precision medicine in realtime at home, a device capable of long distance continuously monitoring target biomolecules in unprocessed blood under dynamic situations is essential. In this study, an integrative buffer free wireless…

We propose a model-free artificial pancreas (AP) for people with type 1 diabetes. The algorithmic parameters are tuned to a virtual population of 1,000,000 individuals, and the AP repeatedly estimates the basal and bolus insulin…

Despite the importance of emphasizing the right psychotherapy treatment for an individual patient, assessing the outcome of the therapy session is equally crucial. Evidence showed that continuous monitoring patient's progress can…

Computation and Language · Computer Science 2022-12-19 Noor Fazilla Abd Yusof , Chenghua Lin

We present GlucOS, a novel system for trustworthy automated insulin delivery. Fundamentally, this paper is about a system we designed, implemented, and deployed on real humans and the lessons learned from our experiences. GlucOS introduces…

Cryptography and Security · Computer Science 2025-10-28 Hari Venugopalan , Shreyas Madhav Ambattur Vijayanand , Caleb Stanford , Stephanie Crossen , Samuel T. King

The availability of continuous glucose monitors as over-the-counter commodities have created a unique opportunity to monitor a person's blood glucose levels, forecast blood glucose trajectories and provide automated interventions to prevent…

Machine Learning · Computer Science 2026-04-16 Ebrahim Farahmand , Shovito Barua Soumma , Nooshin Taheri Chatrudi , Hassan Ghasemzadeh

Diabetes is a global epidemic and it is increasing at an alarming rate. The International Diabetes Federation (IDF) projected that the total number of people with diabetes globally may increase by 48%, from 425 million (year 2017) to 629…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Wei Xiang Lim , Zhiyuan Chen , Amr Ahmed , Tissa Chandesa , Iman Liao

An ever broader range of physical platforms provides the possibility to study and engineer quantum dynamics under continuous measurements. In many experimental arrangements the system of interest is monitored by means of an ancillary…

Quantum Physics · Physics 2015-10-19 Ondřej Černotík , Denis V. Vasilyev , Klemens Hammerer

In the Oral Glucose Tolerance Test (OGTT), a patient, after an overnight fast ingests a load of glucose. Then measurements of glucose concentration are taken every 30 minutes during two hours. The test is used to aid diagnosis of diabetes,…

Applications · Statistics 2017-11-27 Miguel Angel Moreles , Joaquin Peña , Paola Vargas , Adriana Monroy , Silvestre Alavez

Previous menstrual health literature highlights a variety of signals not included in existing menstrual trackers because they are either difficult to gather or are not typically associated with menstrual health. Since it has become…

Human-Computer Interaction · Computer Science 2024-09-09 Georgianna Lin , Brenna Li , Helen Li , Chloe Zhao , Khai N Truong , Alex Mariakakis

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

This paper presents a novel approach to noninvasive hyperglycemia monitoring utilizing electrocardiograms (ECG) from an extensive database comprising 1119 subjects. Previous research on hyperglycemia or glucose detection using ECG has been…

Signal Processing · Electrical Eng. & Systems 2024-03-13 MohammadReza Hosseinzadehketilateh , Banafsheh Adami , Nima Karimian

The treatment of obesity and diabetes remains a challenge and the biological mechanisms of these diseases are still not fully understood. Diabetes and obesity are associated with increased risk of the development of cardiovascular…

Other Quantitative Biology · Quantitative Biology 2018-04-13 Rédoane Daoudi

The use of AI analytics in health informatics has seen a rapid growth in recent years. In this talk, we look at AI analytics use in managing chronic health conditions such as diabetes, obesity, etc. We focus on the challenges in managing…

Computers and Society · Computer Science 2024-02-06 Aladdin Ayesh

This paper presents a control algorithm for creating an artificial pancreas for type 1 diabetes, factoring in input saturation for a practical application. By utilizing the parallel distributed compensation and Takagi-Sugeno Fuzzy model, we…

Systems and Control · Electrical Eng. & Systems 2024-08-21 Mohammadreza Ganji , Mahdi Pourgholi

Every year, humanity loses about 1.5 million persons due to diabetic disease. Therefore continuous monitoring of diabetes is highly needed, but the conventional approach, i.e., fingertip pricking, causes mental and physical pain to the…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Abdelrhman Y. Soliman , Ahmed M. Nor , Octavian Fratu , Simona Halunga , Osama A. Omer , Ahmed S. Mubark