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Machine learning for early prediction in medicine has recently shown breakthrough performance, however, the focus on improving prediction accuracy has led to a neglect of faithful explanations that are required to gain the trust of medical…
Generative medical AI now appears fluent and knowledgeable enough to resemble clinical intelligence, encouraging the belief that scaling will make it safe. But clinical reasoning is not text generation. It is a responsibility-bound process…
Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…
In this paper, we design and implement a generic medical knowledge based system (MKBS) for identifying diseases from several symptoms. In this system, some important aspects like knowledge bases system, knowledge representation, inference…
While increasing patients' access to medical documents improves medical care, this benefit is limited by varying health literacy levels and complex medical terminology. Large language models (LLMs) offer solutions by simplifying medical…
We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…
The regression discontinuity (RD) design is a quasi-experimental design that estimates the causal effects of a treatment by exploiting naturally occurring treatment rules. It can be applied in any context where a particular treatment or…
Stigma, a recognized global barrier to effective disease management, impacts social interactions, resource access, and psychological well-being. In this study, we developed a patient-centered framework for deriving design requirements and…
There is a growing interest in creating tools to assist in clinical note generation using the audio of provider-patient encounters. Motivated by this goal and with the help of providers and medical scribes, we developed an annotation scheme…
Personalized medication planning involves selecting medications and determining a dosing schedule to achieve medical goals specific to each individual patient. Previous work successfully demonstrated that automated planners, using general…
An AI design framework was developed based on three core principles, namely understandability, trust, and usability. The framework was conceptualized by synthesizing evidence from the literature and by consulting with experts. The initial…
Background The use of a clinical decision support system for assessing the quality of care, based on computerized clinical guidelines (GLs), is likely to improve care, reduce costs, save time, and enhance the staff's capabilities.…
A common practice in the medical industry is the use of clinical notes, which consist of detailed patient observations. However, electronic health record systems frequently do not contain these observations in a structured format, rendering…
Clinicians are expected to disclose harmful medical errors to patients and families in line with ethical, regulatory, and patient care standards, yet these conversations remain challenging because of their emotional complexity and limited…
Like other fields of Traditional Medicines, Unani Medicines have been found as an effective medical practice for ages. It is still widely used in the subcontinent, particularly in Pakistan and India. However, Unani Medicines Practitioners…
Understanding decision-making in clinical environments is of paramount importance if we are to bring the strengths of machine learning to ultimately improve patient outcomes. Several factors including the availability of public data, the…
Background: In medical and health professions education (HPE), AI is increasingly used to assess clinical competencies, including via virtual standardized patients. However, most evaluations rely on AI-human interrater reliability and lack…
More than 200 generic drugs approved by the U.S. Food and Drug Administration for non-cancer indications have shown promise for treating cancer. Due to their long history of safe patient use, low cost, and widespread availability,…
As large language models (LLMs) are deployed in high-stakes domains like healthcare, understanding how well their decision-making aligns with human preferences and values becomes crucial, especially when we recognize that there is no single…
As artificial intelligence (AI) becomes increasingly embedded in healthcare delivery, this chapter explores the critical aspects of developing reliable and ethical Clinical Decision Support Systems (CDSS). Beginning with the fundamental…