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Cyanobacteria sequester photosynthetic enzymes into microcompartments which facilitate the conversion of carbon dioxide into sugars. Geometric similarities between these structures and self-assembling viral capsids have inspired models that…

Soft Condensed Matter · Physics 2018-07-10 Grant M. Rotskoff , Phillip L. Geissler

We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation…

Populations and Evolution · Quantitative Biology 2010-07-13 M. E. Cates , D. Marenduzzo , I. Pagonabarraga , J. Tailleur

To characterize the thermodynamical equilibrium of DNA chains interacting with a solution of non-specific binding proteins, a Flory-Huggins free energy model was implemented. We explored the dependence on DNA and protein concentrations of…

Soft Condensed Matter · Physics 2015-11-04 Guillaume Le Treut , François Képès , Henri Orland

Nanoindentation, a common technique for probing the mechanical properties of crystalline materials, exhibits both surface and bulk-dominated responses that are linked to the parent crystal's elasticity and plasticity. For FCC crystals, the…

Materials Science · Physics 2020-02-04 Michail Tzimas , John Michopoulos , Giacomo Po , Andrew C. E. Reid , Stefanos Papanikolaou

Eukaryotic cells demonstrate a wide variety of dynamic patterns of filamentous actin (F-actin) and its regulators. Some of these patterns play important roles in cell functions, such as distinct motility modes, which motivate this study. We…

Pattern Formation and Solitons · Physics 2026-04-13 Jack M. Hughes , Saar Modai , Leah Edelstein-Keshet , Arik Yochelis

For over two decades, Flux Balance Analysis (FBA) has been successfully used for predicting growth rates and intracellular reaction rates in microbiological metabolism. An aspect that is often omitted from this analysis, is segregation or…

Systems and Control · Electrical Eng. & Systems 2023-06-02 Michiel Busschaert , Florence H. Vermeire , Steffen Waldherr

We analyze the molecular dynamics heterogeneity of the liquid crystal 4-n-octyl-4'-cyanobiphenyl nanoconfined in porous silicon. We show that the temperature dependence of the dynamic correlation length ?wall, which measures the distance…

Interaction between hydrogen (H) and metals is central to many materials problems of scientific and technological importance. Chief among them is the development of H storage and H-resistant materials. H segregation or trapping at lattice…

Materials Science · Physics 2013-11-06 Weiwei Xing , Xing-Qiu Chen , Gang Lu , Dianzhong Li , Yiyi Li

Fluid flow has a major effect on the aggregation and fragmentation of bacterial colonies. Yet, a generic framework to understand and predict how hydrodynamics affects colony size remains elusive. This study investigates how fluid flow…

Soft Condensed Matter · Physics 2026-04-21 Yuri Z. Sinzato , Robert Uittenbogaard , Petra M. Visser , Jef Huisman , Maziyar Jalaal

Recent studies have suggested that the Nuclear Pore Complex (NPC) plays a significant role in mechanotransduction. When a force is exerted, the NPC's diameter widens, leading to an increased molecular flux into the nucleus. In this study,…

Biological Physics · Physics 2025-04-09 Atsushi Matsuda , Mohammad R. K. Mofrad

We study the surface diffusion of the model cyanobacterium Synechocystis sp. PCC $6803$ during the incipient stages of cell contact with a glass surface in the dilute regime. We observe a twitching motility with alternating immobile…

DNA-based storage has emerged as a promising alternative to traditional data storage methods, offering unmatched advantages in data density, longevity, and sustainability. Two main approaches have developed: in-vitro storage, where…

Information Theory · Computer Science 2026-04-29 Liav Koram , Ohad Elishco

The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

Biological Physics · Physics 2019-01-17 John J. Molina , Ryoichi Yamamoto

During batch growth on mixtures of two growth-limiting substrates, microbes consume the substrates either sequentially or simultaneously. These growth patterns are manifested in all types of bacteria and yeasts. The ubiquity of these growth…

Cell Behavior · Quantitative Biology 2008-01-09 Jason T. Noel , Atul Narang

We study the clustering of a model cyanobacterium \textit{Synechocystis} into microcolonies. The bacteria are allowed to diffuse onto surfaces of different hardness, and interact with the others by aggregation and detachment. We find that…

Biological Physics · Physics 2020-03-04 Thomas Vourc'h , Julien Léopoldès , Hassan Peerhossaini

In response to natural or anthropocentric pollutions coupled to global climate changes, microorganisms from aquatic environments can suddenly accumulate on water surface. These dense suspensions, known as blooms, are harmful to ecosystems…

Biological Physics · Physics 2015-11-16 Julien Dervaux , Annick Méjean , Philippe Brunet

Biological systems are majorly dependent on their property of bistability in order to exhibit nongenetic heterogeneity in terms of cellular morphology and physiology. Spatial patterns of phenotypically heterogeneous cells, arising due to…

Quantitative Methods · Quantitative Biology 2023-01-25 Priya Chakraborty , Ushasi Roy , Mohit K. Jolly , Sayantari Ghosh

Cells control the size and organization of biomolecular condensates formed by liquid-liquid phase separation (LLPS), but multiple mechanisms likely contribute to this control and remain to be fully elucidated. Here we propose a…

Biological Physics · Physics 2026-04-10 Le Qiao , Peter Gispert , Lukas S. Stelzl , Friederike Schmid

To assess long-term structural integrity under operational conditions in nuclear reactors, SS 316LN with varying nitrogen content is subjected to thermal aging for 20000 hours at 650{\deg}C. While the annealing twins and heterogeneous grain…

How do phase separated cellular structures set their size? To elucidate this, we study the dynamics and steady states of a phase separating nucleator that is advected by the self-straining cytoskeletal network which it nucleates. We find…