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We present a fully discrete stability analysis of the domain-of-dependence stabilization for hyperbolic problems. The method aims to address issues caused by small cut cells by redistributing mass around the neighborhood of a small cut cell…

Numerical Analysis · Mathematics 2026-05-07 Louis Petri , Gunnar Birke , Christian Engwer , Hendrik Ranocha

We present a novel Neural Embedding Spatio-Temporal (NEST) point process model for spatio-temporal discrete event data and develop an efficient imitation learning (a type of reinforcement learning) based approach for model fitting. Despite…

Machine Learning · Computer Science 2021-01-25 Shixiang Zhu , Shuang Li , Zhigang Peng , Yao Xie

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak

Cell sorting, the segregation of cells with different properties into distinct domains, is a key phenomenon in biological processes such as embryogenesis. We use a phase-field model of a confluent cell layer to study the role of activity in…

Biological Physics · Physics 2024-03-05 James N. Graham , Guanming Zhang , Julia M. Yeomans

Isologous diversification theory for cell differentiation is proposed, based on simulations of interacting cells with biochemical networks and cell division process following consumption of some chemicals. According to the simulations of…

adap-org · Physics 2008-02-03 Kunihiko Kaneko , Tetsuya Yomo

Transitive consistency is an intrinsic property for collections of linear invertible transformations between Euclidean coordinate frames. In practice, when the transformations are estimated from data, this property is lacking. This work…

Optimization and Control · Mathematics 2015-09-03 Johan Thunberg , Florian Bernard , Jorge Goncalves

Protein pattern formation is essential for the spatial organization of many intracellular processes like cell division, flagellum positioning, and chemotaxis. A prominent example of intracellular patterns are the oscillatory pole-to-pole…

Biological Physics · Physics 2018-02-21 Erwin Frey , Jacob Halatek , Simon Kretschmer , Petra Schwille

A ubiquitous feature of living cells is their growth over time followed by division into daughter cells. How isogenic cell populations maintain size homeostasis, i.e., a narrow distribution of cell size, is an intriguing fundamental…

Cell Behavior · Quantitative Biology 2016-06-03 César Augusto Vargas-García , Mohammad Soltani , Abhyudai Singh

The performance of cellular system significantly depends on its network topology, where the spatial deployment of base stations (BSs) plays a key role in the downlink scenario. Moreover, cellular networks are undergoing a heterogeneous…

Networking and Internet Architecture · Computer Science 2014-11-11 Yifan Zhou , Zhifeng Zhao , Qianlan Ying , Rongpeng Li , Xuan Zhou , Xianfu Chen , Honggang Zhang

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

Evolving data streams induce joint nonstationarity in continual semantic segmentation, where semantic classes, input distributions, and supervision availability change simultaneously over time. This setting reflects practical structured…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Prashant Pandey , Himanshu Kumar , Devineni Sri Venkatraya Chowdary , Brejesh Lall

The present paper studies existence and distributional uniqueness of subclasses of stationary hard-core particle systems arising as thinnings of stationary particle processes. These subclasses are defined by natural maximality criteria. We…

Probability · Mathematics 2018-01-17 Christian Hirsch , Günter Last

A simple model of particle creation and annihilation in an isolated assembly of particles with conserved energy and fixed volume, the Cell Model, is formulated. With increasing time, particle number distribution, obtained by averaging over…

Nuclear Theory · Physics 2018-04-25 M. Gazdzicki , M. I. Gorenstein , A. Fronczak , P. Fronczak , M. Mackowiak-Pawlowska

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

In this paper, we exploit the theory of dense graph limits to provide a new framework to study the stability of graph partitioning methods, which we call structural consistency. Both stability under perturbation as well as asymptotic…

Combinatorics · Mathematics 2016-08-15 Peter Diao , Dominique Guillot , Apoorva Khare , Bala Rajaratnam

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

Developing epithelial tissues coordinate cell proliferation and mechanical forces to achieve proper size and shape. As epithelial cells tightly adhere together to form the confluent tissue, the distribution of cell areas significantly…

Biological Physics · Physics 2026-01-22 Michael F. Staddon , Natalie A. Dye , Marko Popović , Frank Jülicher

The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth,…

Biological Physics · Physics 2024-04-10 Johannes C. Krämer , Edouard Hannezo , Gerhard Gompper , Jens Elgeti

Segregation of populations is a key question in evolution theory. One important aspect is the relation between spatial organization and the population's composition. Here we study a specific example -- sectors in expanding bacterial…

Condensed Matter · Physics 2009-10-31 Ido Golding , Inon Cohen , Eshel Ben-Jacob

During development, spatio-temporal patterns ranging from checkerboard to engulfing occur with precise proportions of the respective cell fates. Key developmental regulators are intracellular transcriptional interactions and intercellular…

Biological Physics · Physics 2022-11-15 Simon Schardt , Sabine C. Fischer
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