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A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter

Understanding infectious disease transmission in institutional settings requires models that capture how contacts arise from structured routines, roles, and spatial constraints. In aged care facilities, interactions are driven by care…

Populations and Evolution · Quantitative Biology 2026-03-19 Haley Stone , C. Raina MacIntyre , Mohana Kunasekaran , Chris Poulos , David Heslop

Emerging empirical and theoretical thinking about human aging places considerable value upon the role of the environment as a major factor which can promote prolonged healthy longevity. Our contemporary, information-rich environment is…

Other Quantitative Biology · Quantitative Biology 2014-07-24 Marios Kyriazis

We construct a model of cell reprogramming (the conversion of fully differentiated cells to a state of pluripotency, known as induced pluripotent stem cells, or iPSCs) which builds on key elements of cell biology viz. cell cycles and cell…

Cell Behavior · Quantitative Biology 2017-09-25 R Hannam , A Annibale , R Kuehn

The high energy transfer efficiency of photosynthetic complexes has been a topic of research across many disciplines. Several attempts have been made in order to explain this energy transfer enhancement in terms of quantum mechanical…

Quantum Physics · Physics 2022-09-02 Ali Pedram , Barış Çakmak , Özgür E. Müstecaplıoğlu

We consider the dynamics of a simple one dimensional model and we discuss the phenomenon of aging (i.e., the strong dependence of the dynamical correlation functions over the waiting time). Our model is the so-called random random walk, the…

Condensed Matter · Physics 2009-10-22 Enzo Marinari , Giorgio Parisi

A mechanism of point defect migration triggered by local depolarization fields is shown to explain some still inexplicable features of aging in acceptor doped ferroelectrics. A drift-diffusion model of the coupled charged defect transport…

Materials Science · Physics 2009-11-13 Yuri A. Genenko

We study the effect of physical aging on the mechanical properties of a model polymer glass using molecular dynamics simulations. The creep compliance is determined simultaneously with the structural relaxation under a constant uniaxial…

Soft Condensed Matter · Physics 2009-11-13 Mya Warren , Joerg Rottler

The stacked contact process is a three-state spin system that describes the co-evolution of a population of hosts together with their symbionts. In a nutshell, the hosts evolve according to a contact process while the symbionts evolve…

Probability · Mathematics 2020-05-06 Eric Foxall , Nicolas Lanchier

In this paper, a model for understanding the effects of selection using systems- level computational approaches is introduced. A number of concepts and principles essential for understanding the motivation for constructing the model will be…

Populations and Evolution · Quantitative Biology 2009-03-04 Bradly Alicea

We construct a seven-component model of the in-host dynamics of the Human Immunodeficiency Virus Type-1 (i.e, HIV) that accounts for latent infection and the propensity of viral mutation. A dynamical analysis is conducted and a theorem is…

Populations and Evolution · Quantitative Biology 2016-04-18 Stephen Pankavich , Deborah Shutt

We show aging of Glauber-type dynamics on the random energy model, in the sense that we obtain the scaling limits of the clock process and of the age process. The latter encodes the Gibbs weight of the configuration occupied by the…

Probability · Mathematics 2013-03-21 Pierre Mathieu , Jean-Christophe Mourrat

Many real-world complex networks arise as a result of a competition between growth and rewiring processes. Usually the initial part of the evolution is dominated by growth while the later one rather by rewiring. The initial growth allows…

Statistical Mechanics · Physics 2020-10-07 Zdzislaw Burda , Michalina Kotwica , Krzysztof Malarz

Aging refers to the evolution of system properties with waiting time $t_w$. It is a key feature of glassy dynamics. Recent experiments have demonstrated aging in biological systems that are inherently active with a magnitude of…

Soft Condensed Matter · Physics 2026-04-10 Soumitra Kolya , Nir S. Gov , Saroj Kumar Nandi

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Hypothesis: Aging in colloidal suspensions manifests as a reduction in kinetic freedom of the colloids. In aqueous suspensions of charged colloids, the role of inter-particle electrostatics interactions on the aging dynamics is well…

Soft Condensed Matter · Physics 2021-06-17 Chandeshwar Misra , Venketesh T Ranganathan , Ranjini Bandyopadhyay

We present a study of humidity effects on the maximum stability angle in granular media. We show that a granular medium of small glass beads exhibits aging properties : the first avalanche angle increases logarithmically with the resting…

Soft Condensed Matter · Physics 2007-05-23 F. Restagno , H. Gayvallet , L. Bocquet , E. Charlaix

The paper discusses a connection between asymmetric reproduction -- that is reproduction in a parent-child relationship where the parent does not mutate during reproduction --, the fact that all non-viral lifeforms bear genes of their…

Populations and Evolution · Quantitative Biology 2015-08-11 Norbert Michael Mayer

Analysis of experimental kinetic dependences and results of the computer modeling of pairwise interactions in the heterogeneous system have shown that a character of its fractal property variation in the evolution process would be different…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 K. S. Baktybekov , S. G. Karstina , E. N. Vertyagina , A. A. Baratova

Kingman's House-of-Cards model is a simple and celebrated model to describe the evolution of population under the competition of selection and mutation. Letting mutation probabilities vary on generations makes the model more realistic and…

Probability · Mathematics 2019-11-26 Linglong Yuan
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