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Imaging of microvasculature is primarily performed with X-ray contrast agents, owing to the wide availability of absorption-contrast laboratory source microCT compared to phase contrast capable devices. Standard commercial contrast agents…
Among the research efforts to segment the retinal vasculature from fundus images, deep learning models consistently achieve superior performance. However, this data-driven approach is very sensitive to domain shifts. For fundus images, such…
Existing methods to reconstruct vascular structures from a computed tomography (CT) angiogram rely on injection of intravenous contrast to enhance the radio-density within the vessel lumen. However, pathological changes can be present in…
Recently, a new detector concept, for combined imaging and spectroscopy of fast-neutrons and gamma was presented. It encompasses a liquid-xenon (LXe) converter-scintillator coupled to a UV-sensitive gaseous Thick Gas Electron Multiplier…
Laser Doppler holography (LDH) is a full-field imaging technique that was recently used in the human eye to reveal blood flow contrasts in the retinal and choroidal vasculature non-invasively, and with high temporal resolution. We here…
Vascular diseases pose a significant threat to human health, with X-ray angiography established as the gold standard for diagnosis, allowing for detailed observation of blood vessels. However, angiographic X-rays expose personnel and…
We have developed and successfully tested a prototype of a new type of high position resolution hybrid X-ray detector. It contains a thin wall lead glass capillary plate converter of X-rays combined with a microgap parallel-plate avalanche…
(abridged) Vortex coronagraphs are among the most promising solutions to perform high contrast imaging at small angular separations. They feature a very small inner working angle, a clear 360 degree discovery space, have demonstrated very…
Pulmonary hypertension (PH) can lead to significant vascular remodeling, resulting in altered pulmonary blood flow. Estimating the patient-specific contributions of each remodeling event is necessary to optimize and individualize clinical…
Context. High contrast imaging has thoroughly combed through the limited search space accessible with first-generation ground-based adaptive optics instruments and the Hubble Space Telescope. Only a few objects were discovered, and many…
Coronary angiography (CAG) is the gold-standard imaging modality for evaluating coronary artery disease, but its interpretation and subsequent treatment planning rely heavily on expert cardiologists. To enable AI-based decision support, we…
Microvascular imaging has advanced significantly with ultrafast data acquisition and improved clutter filtering, enhancing the sensitivity of power Doppler imaging to small vessels. However, the image quality remains limited by spatial…
White light endoscopy is the clinical gold standard for detecting diseases in the gastrointestinal tract. Most applications involve identifying visual abnormalities in tissue color, texture, and shape. Unfortunately, the contrast of these…
Coronagraphy is a powerful technique to achieve high contrast imaging and hence to image faint companions around bright targets. Various concepts have been used in the visible and near-infrared regimes, while coronagraphic applications in…
Existing Medical Large Vision-Language Models (Med-LVLMs), encapsulating extensive medical knowledge, demonstrate excellent capabilities in understanding medical images. However, there remain challenges in visual localization in medical…
Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…
Gallium-based liquid metals have recently been found important in a variety of newly emerging applications such as room temperature metal 3D printing, direct writing of electronics and biomedicine etc. In all these practices, one frequently…
Iodinated contrast agents are widely utilized in numerous interventional procedures, yet posing substantial health risks to patients. This paper presents CAS-GAN, a novel GAN framework that serves as a "virtual contrast agent" to synthesize…
Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…
Presented here are first tests of a Gaseous Photomultiplier based on a cascade of Thick GEM structures intended for gamma-ray position reconstruction in liquid Argon. The detector has a MgF$_2$ window, transparent to VUV light, and a CsI…