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Divergence between populations for a given trait can be driven by natural or sexual selection, interacting with migration behaviour. Mating preference for different phenotypes can lead to the emergence and persistence of differentiated…

Populations and Evolution · Quantitative Biology 2018-01-25 Charline Smadi , Helene Leman , Violaine Llaurens

We consider an infinitely large population under stabilising selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a…

Populations and Evolution · Quantitative Biology 2016-01-13 Kavita Jain , Wolfgang Stephan

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or…

Populations and Evolution · Quantitative Biology 2013-03-05 Richard A. Neher , Oskar Hallatschek

Since steep declines in a population's size also typically alter its composition, population bottlenecks are considered highly important for evolution. However, despite such significance, the mechanisms governing the impact of a given…

Populations and Evolution · Quantitative Biology 2022-06-28 Emanuele Crosato , Jeffrey N. Philippson , Shashi Thutupalli , Richard G. Morris

Gene drive alleles bias their own inheritance to offspring. They can fix in a wild-type population in spite of a fitness cost, and even lead to the eradication of the target population if the fitness cost is high. However, this outcome may…

Populations and Evolution · Quantitative Biology 2026-04-30 Léna Kläy , Léo Girardin , Florence Débarre , Vincent Calvez

The evolution of cooperation often depends upon population structure, yet nearly all models of cooperation implicitly assume that this structure remains static. This is a simplifying assumption, because most organisms possess genetic traits…

Populations and Evolution · Quantitative Biology 2012-08-03 Simon T. Powers , Alexandra S. Penn , Richard A. Watson

We study the influence of stochastic effects due to finite population size in the evolutionary dynamics of populations interacting in the multi-person Prisoner's Dilemma game. This paper is an extension of the investigation presented in a…

Populations and Evolution · Quantitative Biology 2007-05-23 Anders Eriksson , Kristian Lindgren

There is an urgent and well-recognized need to extend genetic studies to diverse populations, but several obstacles continue to be prohibitive, including (but not limited to) the difficulty of recruiting individuals from diverse populations…

Populations and Evolution · Quantitative Biology 2021-09-28 Charleston W. K. Chiang

Horizontal gene transfer consists in exchanging genetic materials between microorganisms during their lives. This is a major mechanism of bacterial evolution and is believed to be of main importance in antibiotics resistance. We consider a…

Probability · Mathematics 2019-12-18 Nicolas Champagnat , Sylvie Méléard , Viet Chi Tran

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

The search ability of an Evolutionary Algorithm (EA) depends on the variation among the individuals in the population. Maintaining an optimal level of diversity in the EA population is imperative to ensure that progress of the EA search is…

Neural and Evolutionary Computing · Computer Science 2014-11-18 Maumita Bhattacharya

Selection, mutation and random drift affect the dynamics of allele frequencies and consequently of quantitative traits. While the macroscopic dynamics of quantitative traits can be measured, the underlying allele frequencies are typically…

Populations and Evolution · Quantitative Biology 2016-03-15 Katarína Boďová , Gašper Tkačik , Nicholas H. Barton

One of the key difficulties in using estimation-of-distribution algorithms is choosing the population size(s) appropriately: Too small values lead to genetic drift, which can cause enormous difficulties. In the regime with no genetic drift,…

Neural and Evolutionary Computing · Computer Science 2023-09-11 Benjamin Doerr , Weijie Zheng

Species introductions to new habitats can cause a decline in the population size of competing native species and consequently also in their genetic diversity. We are interested in why these adverse effects are weak in some cases whereas in…

Populations and Evolution · Quantitative Biology 2013-01-03 Meike J. Wittmann , Martin Hutzenthaler , Wilfried Gabriel , Dirk Metzler

The question of whether biological populations survive or are eventually driven to extinction has long been examined using mathematical models. In this work we study population survival or extinction using a stochastic, discrete…

Populations and Evolution · Quantitative Biology 2021-09-15 Yifei Li , Stuart T. Johnston , Pascal R. Buenzli , Peter van Heijster , Matthew J. Simpson

The evolutionary edit distance between two individuals in a population, i.e., the amount of applications of any genetic operator it would take the evolutionary process to generate one individual starting from the other, seems like a…

Neural and Evolutionary Computing · Computer Science 2017-05-01 Thomas Gabor , Lenz Belzner

Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

Populations and Evolution · Quantitative Biology 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

Evolution occurs in populations of reproducing individuals. The structure of a biological population affects which traits evolve. Understanding evolutionary game dynamics in structured populations is difficult. Precise results have been…

Populations and Evolution · Quantitative Biology 2017-08-16 Benjamin Allen , Gabor Lippner , Yu-Ting Chen , Babak Fotouhi , Naghmeh Momeni , Martin A. Nowak , Shing-Tung Yau

The accumulation of beneficial mutations on many competing genetic backgrounds in rapidly adapting populations has a striking impact on evolutionary dynamics. This effect, known as clonal interference, causes erratic fluctuations in the…

Populations and Evolution · Quantitative Biology 2013-05-31 Katya Kosheleva , Michael Desai

Observed differences in mean phenotypic values across human groups have attracted renewed interest with the rise of large-scale genomic studies and polygenic risk prediction. However, the genetic basis of these differences is far more…

Populations and Evolution · Quantitative Biology 2026-05-25 Nicole Kleman , Meng Lin , Christopher R. Gignoux , Arslan A. Zaidi
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