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We consider a Markov-modulated Brownian motion $\{Y(t), \rho(t)\}$ with two boundaries at $0$ and $b > 0$, and allow for the controlling Markov chain $\{\rho(t)\}$ to instantaneously undergo a change of phase upon hitting either of the two…

Probability · Mathematics 2016-03-08 Guy Latouche , Giang T. Nguyen

We study the performance limits of state-dependent discrete memoryless channels with a discrete state available at both the encoder and the decoder. We establish the epsilon-capacity as well as necessary and sufficient conditions for the…

Information Theory · Computer Science 2014-07-16 Marco Tomamichel , Vincent Y. F. Tan

Inferring the causal structure underlying stochastic dynamical systems from observational data holds great promise in domains ranging from science and health to finance. Such processes can often be accurately modeled via stochastic…

Machine Learning · Computer Science 2025-03-04 Georg Manten , Cecilia Casolo , Emilio Ferrucci , Søren Wengel Mogensen , Cristopher Salvi , Niki Kilbertus

Periodic boundary conditions when applied to staggered grids, which define variables on both cell edges and cell centers, can be shown to have a problem with uniqueness of variables at cell edges depending on the number of points in the…

Mathematical Physics · Physics 2024-10-01 Divyanshu Gola

The previously formulated model for the evolution of the genetic code was shown to clarify why base triplets of some precursor amino acids differ by a single base from product amino acid codons, while others show less homology. First, the…

Biological Physics · Physics 2007-05-23 Brian K. Davis

Two known results on the relationship between conditional and unconditional independence are obtained as a consequence of the main result of this paper, a theorem that uses independence of Markov kernels to obtain a minimal condition which…

Statistics Theory · Mathematics 2021-10-28 A. G. Nogales , P. Pérez

Laboratory experiments with bacterial colonies, under well-controlled conditions often lead to evolutionary diversification, where at least two ecotypes emerge from an initially monomorphic population. Empirical evidence suggests that such…

Populations and Evolution · Quantitative Biology 2024-11-06 Roberto Corral López , Samir Suweis , Sandro Azaele , Miguel A. Muñoz

In special coordinates (codon position--specific nucleotide frequencies) bacterial genomes form two straight lines in 9-dimensional space: one line for eubacterial genomes, another for archaeal genomes. All the 348 distinct bacterial…

Genomics · Quantitative Biology 2007-11-13 A. N. Gorban , A. Yu. Zinovyev

Markov networks are probabilistic graphical models that employ undirected graphs to depict conditional independence relationships among variables. Our focus lies in constraint-based structure learning, which entails learning the undirected…

Machine Learning · Computer Science 2024-03-14 Tuukka Korhonen , Fedor V. Fomin , Pekka Parviainen

Antiterminators are essential components of bacterial transcriptional regulation, allowing the control of gene expression in response to fluctuating environmental conditions. Among them, RNA-binding antiterminator proteins play a major role…

Molecular Networks · Quantitative Biology 2025-09-17 Diane Soussan , Ali Tahrioui , Rafael Ruiz de la Haba , Adrien Forge , Sylvie Chevalier , Olivier Lesouhaitier , Cécile Muller

Perturbation analysis of Markov chains provides bounds on the effect that a change in a Markov transition matrix has on the corresponding stationary distribution. This paper compares and analyzes bounds found in the literature for finite…

Probability · Mathematics 2024-04-03 Karim Abbas , Joost Berkhout , Bernd Heidergott

Let $(X_n \colon n\in\Z)$ be a two-sided recurrent Markov chain with fixed initial state $X_0$ and let $\nu$ be a probability measure on its state space. We give a necessary and sufficient criterion for the existence of a non-randomized…

Probability · Mathematics 2015-06-11 Peter Morters , Istvan Redl

Bacteria pose unique challenges for genome-wide association studies (GWAS) because of strong structuring into distinct strains and substantial linkage disequilibrium across the genome. While methods developed for human studies can correct…

In this review-type paper written at the occasion of the Oberwolfach workshop {\em One-sided vs. Two-sided stochastic processes} (february 22-29, 2020), we discuss and compare Markov properties and generalisations thereof in more…

Probability · Mathematics 2020-12-01 Aernout van Enter , Arnaud Le Ny , Frédéric Paccaut

Inferring dependence structure through undirected graphs is crucial for uncovering the major modes of multivariate interaction among high-dimensional genomic markers that are potentially associated with cancer. Traditionally, conditional…

Methodology · Statistics 2016-04-04 Anindya Bhadra , Arvind Rao , Veerabhadran Baladandayuthapani

Two recent and seemingly-unrelated techniques for proving mixing bounds for Markov chains are: (i) the framework of Spectral Independence, introduced by Anari, Liu and Oveis Gharan, and its numerous extensions, which have given rise to…

Probability · Mathematics 2022-06-07 Yuansi Chen , Ronen Eldan

Nonlinear Markov chains with finite state space have been introduced in Kolokoltsov (2010). The characteristic property of these processes is that the transition probabilities do not only depend on the state, but also on the distribution of…

Probability · Mathematics 2020-07-07 Berenice Anne Neumann

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

Populations and Evolution · Quantitative Biology 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

We rigorously prove a form of disorder-resistance for a class of one-dimensional cellular automaton rules, including some that arise as boundary dynamics of two-dimensional solidification rules. Specifically, when started from a random…

Probability · Mathematics 2015-09-30 Janko Gravner , Alexander E. Holroyd

This paper studies limit theorems for Markov Chains with general state space under conditions which imply subgeometric ergodicity. We obtain a central limit theorem and moderate deviation principles for additive not necessarily bounded…

Probability · Mathematics 2007-05-23 Randal Douc , Arnaud Guillin , Eric Moulines