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Ordinary differential equation models are nowadays widely used for the mechanistic description of biological processes and their temporal evolution. These models typically have many unknown and non-measurable parameters, which have to be…

Quantitative Methods · Quantitative Biology 2021-05-27 Alejandro F. Villaverde , Dilan Pathirana , Fabian Fröhlich , Jan Hasenauer , Julio R. Banga

Stochastic differential equations (SDEs) are established tools to model physical phenomena whose dynamics are affected by random noise. By estimating parameters of an SDE intrinsic randomness of a system around its drift can be identified…

Computation · Statistics 2012-05-03 Umberto Picchini , Susanne Ditlevsen

In this paper an efficient model based diagnostic process is described for systems whose components possess a causal relation between their inputs and their outputs. In this diagnostic process, firstly, a set of focuses on likely broken…

Artificial Intelligence · Computer Science 2022-09-21 Nico Roos

Limit cycle oscillations are phenomena arising in nonlinear dynamical systems and characterized by periodic, locally-stable, and self-sustained state trajectories. Systems controlled in a closed loop along a periodic trajectory can also be…

Systems and Control · Electrical Eng. & Systems 2023-03-20 Defne E. Ozan , Mingzhou Yin , Andrea Iannelli , Roy S. Smith

The dynamic behaviour of a power system can be described by a system of differential-algebraic equations. Time-domain simulations are used to simulate the evolution of these dynamics. They often require the use of small time step sizes and…

Systems and Control · Electrical Eng. & Systems 2024-07-08 Jochen Stiasny , Baosen Zhang , Spyros Chatzivasileiadis

Physics-informed neural networks (PINNs) are an emerging technique to solve partial differential equations (PDEs). In this work, we propose a simple but effective PINN approach for the phase-field model of ferroelectric microstructure…

Materials Science · Physics 2024-09-06 Lan Shang , Sizheng Zheng , Jin Wang , Jie Wang

Previous work introduced a lower-dimensional numerical model for the geometric nonlinear simulation and optimization of compliant pressure actuated cellular structures. This model takes into account hinge eccentricities as well as…

Quantitative Methods · Quantitative Biology 2017-07-31 Markus Pagitz , Remco I. Leine

Recently, we have demonstrated that our approach is a highly effective tool while analysing complex phenomena existing in networks of coupled nonlinear systems. In the present article we present the results of our investigations into a…

Dynamical Systems · Mathematics 2025-07-04 Volodymyr Denysenko , Artur Dabrowski

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

Biomolecules · Quantitative Biology 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

Multiscale dynamical systems, modeled by high-dimensional stiff ordinary differential equations (ODEs) with wide-ranging characteristic timescales, arise across diverse fields of science and engineering, but their numerical solvers often…

Numerical Analysis · Mathematics 2025-08-14 Junjie Yao , Yuxiao Yi , Liangkai Hang , Weinan E , Weizong Wang , Yaoyu Zhang , Tianhan Zhang , Zhi-Qin John Xu

Process mining provides methods to analyse event logs generated by information systems during the execution of processes. It thereby supports the design, validation, and execution of processes in domains ranging from healthcare, through…

Databases · Computer Science 2024-02-06 Mehdi Acheli , Daniela Grigori , Matthias Weidlich

Inferring the structure and dynamics of network models is critical to understanding the functionality and control of complex systems, such as metabolic and regulatory biological networks. The increasing quality and quantity of experimental…

Dynamical Systems · Mathematics 2016-05-27 Niall M. Mangan , Steven L. Brunton , Joshua L. Proctor , J. Nathan Kutz

Identifying accurate dynamic models is required for the simulation and control of various technical systems. In many important real-world applications, however, the two main modeling approaches often fail to meet requirements: first…

Machine Learning · Computer Science 2021-04-19 Manuel A. Roehrl , Thomas A. Runkler , Veronika Brandtstetter , Michel Tokic , Stefan Obermayer

In many scientific fields, the generation and evolution of data are governed by partial differential equations (PDEs) which are typically informed by established physical laws at the macroscopic level to describe general and predictable…

Methodology · Statistics 2025-07-01 Ziyuan Chen , Shunxing Yan , Fang Yao

Discovering dynamical models to describe underlying dynamical behavior is essential to draw decisive conclusions and engineering studies, e.g., optimizing a process. Experimental data availability notwithstanding has increased…

Machine Learning · Computer Science 2022-10-12 Pawan Goyal , Peter Benner

Simple models have been used to describe ecological processes for over a century. However, the complexity of ecological systems makes simple models subject to modeling bias due to simplifying assumptions or unaccounted factors, limiting…

Quantitative Methods · Quantitative Biology 2024-01-24 Jorge Arroyo-Esquivel , Christopher A Klausmeier , Elena Litchman

Differential Evolution (DE) is a renowned optimization stratagem that can easily solve nonlinear and comprehensive problems. DE is a well known and uncomplicated population based probabilistic approach for comprehensive optimization. It has…

Neural and Evolutionary Computing · Computer Science 2015-06-22 Sandeep Kumar , Vivek Kumar Sharma , Rajani Kumari

Persistence of excitation (PE) is an important requirement for the successful operation of data-driven predictive control, as it ensures that the input-output data contains sufficient information about the underlying system dynamics.…

Systems and Control · Electrical Eng. & Systems 2025-09-08 Lucca Heinze Faro , Yuanbo Nie , Paul Trodden

Equilibrium formally can be represented as an ensemble of uncoupled systems undergoing unbiased dynamics in which detailed balance is maintained. Many non-equilibrium processes can be described by suitable subsets of the equilibrium…

The discipline of process mining deals with analyzing execution data of operational processes, extracting models from event data, checking the conformance between event data and normative models, and enhancing all aspects of processes.…

Data Structures and Algorithms · Computer Science 2022-04-11 Marco Pegoraro , Merih Seran Uysal , Wil M. P. van der Aalst
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