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Data-intensive science communities are progressively adopting FAIR practices that enhance the visibility of scientific breakthroughs and enable reuse. At the core of this movement, research objects contain and describe scientific…

Referring understanding is a fundamental task that bridges natural language and visual content by localizing objects described in free-form expressions. However, existing works are constrained by limited language expressiveness, lacking the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yani Zhang , Dongming Wu , Wencheng Han , Xingping Dong

Motivation: The rapid growth of biological data has intensified the need for transparent, reproducible, and well-documented computational workflows. The ability to clearly connect the steps of a workflow in the code with their description…

Computation and Language · Computer Science 2026-03-10 Clémence Sebe , Olivier Ferret , Aurélie Névéol , Mahdi Esmailoghli , Ulf Leser , Sarah Cohen-Boulakia

Meta-learning is a line of research that develops the ability to leverage past experiences to efficiently solve new learning problems. Meta-Reinforcement Learning (meta-RL) methods demonstrate a capability to learn behaviors that…

Machine Learning · Computer Science 2022-08-25 Brieuc Pinon , Jean-Charles Delvenne , Raphaël Jungers

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

As sequencing technologies become more affordable and genomic databases expand continuously, the reuse of publicly available sequencing data emerges as a powerful strategy for studying microbial pathogens. Indeed, raw sequencing reads…

Quantitative Methods · Quantitative Biology 2025-05-16 Damien Richard , Nils Poulicard

The establishment of links between data (e.g., patient records) and Web resources (e.g., literature) and the proper visualization of such discovered knowledge is still a challenge in most Life Science domains (e.g., biomedicine). In this…

Information Retrieval · Computer Science 2010-12-09 R. Berlanga , E. Jimenez-Ruiz , V. Nebot

Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based…

Biological Physics · Physics 2016-10-31 Marco Di Stefano , Jonas Paulsen , Tonje G. Lien , Eivind Hovig , Cristian Micheletti

Due to the complexity of robotics, the reproducibility of results and experiments is one of the fundamental problems in robotics research. While the problem has been identified by the community, the approaches that address the problem…

Robotics · Computer Science 2018-01-26 Aljoscha Pörtner , Martin Hoffmann , Matthias König

While automated experiments and high-throughput methods are becoming more mainstream in the age of data, empowering individual researchers to capture, collate, and contextualize their data faster and more reproducibly still remains a…

Computers and Society · Computer Science 2020-07-30 Ha-Kyung Kwon , Chirranjeevi Balaji Gopal , Jared Kirschner , Santiago Caicedo , Brian D. Storey

In the field of computational science and engineering, workflows often entail the application of various software, for instance, for simulation or pre- and postprocessing. Typically, these components have to be combined in arbitrarily…

Software Engineering · Computer Science 2022-11-15 Philipp Diercks , Dennis Gläser , Ontje Lünsdorf , Michael Selzer , Bernd Flemisch , Jörg F. Unger

Object-Centric Process Mining enables the analysis of complex operational behavior by capturing interactions among multiple business objects (e.g., orders, items, deliveries). These interactions are recorded using Object-Centric Event Data…

Databases · Computer Science 2025-08-27 Shahrzad Khayatbashi , Majid Rafiei , Jiayuan Chen , Timotheus Kampik , Gregor Berg , Amin Jalali

The genome-scale metabolic model with protein constraint (PC-model) has been increasingly popular for microbial metabolic simulations. We present PROSO Toolbox, a unified and simple-to-use PC-model toolbox that takes any high-quality…

Molecular Networks · Quantitative Biology 2023-08-30 Haoyang Yao , Laurence Yang

The visual analysis of retinal data contributes to the understanding of a wide range of eye diseases. For the evaluation of cross-sectional studies, ophthalmologists rely on workflows and toolsets established in their work environment. That…

Human-Computer Interaction · Computer Science 2023-01-06 Martin Röhlig , Lars Nonnemann , Hans-Jörg Schulz , Oliver Stachs , Heidrun Schumann

It is prominently recognized that dataset development in machine learning is a value-laden process from problem formulation to data processing, use, and reuse. Structured documentation frameworks such as datasheets, data statements, and…

Computers and Society · Computer Science 2026-05-13 Eshta Bhardwaj , Ciara Zogheib , Christoph Becker

The best way to model, understand, and quantify the information contained in complex systems is an open question in physics, mathematics, and computer science. The uncertain relationship between entropy and complexity further complicates…

Machine Learning · Computer Science 2022-11-10 Stephen Casey

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

Artificial intelligence is transforming molecular and materials science, but its growing computational and data demands raise critical sustainability challenges. In this Perspective, we examine resource considerations across the AI-driven…

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman