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In various applications, the potential outcome of a unit may be influenced by the treatments received by other units, a phenomenon known as interference, as well as by prior treatments, referred to as carryover effects. These phenomena…

Methodology · Statistics 2025-01-27 Haoyang Yu , Wei Ma , Hanzhong Liu

The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient…

In this paper we consider the problem of constructing $T$-optimal discriminating designs for Fourier regression models. We provide explicit solutions of the optimal design problem for discriminating between two Fourier regression models,…

Methodology · Statistics 2015-12-24 Holger Dette , Viatcheslav B. Melas , Petr Shpilev

We consider optimal non-sequential designs for a large class of (linear and nonlinear) regression models involving polynomials and rational functions with heteroscedastic noise also given by a polynomial or rational weight function. The…

Computation · Statistics 2011-08-30 Dávid Papp

The aim of this paper is to characterize and construct universally optimal designs among the class of circular repeated-measurements designs when the parameters do not permit balance for carry-over effects. It is shown that some circular…

Statistics Theory · Mathematics 2014-10-08 R. A. Bailey , Peter J. Cameron , Katarzyna Filipiak , Joachim Kunert , Augustyn Markiewicz

The purpose of this short note is to show that the Christoffel-Darboux polynomial, useful in approximation theory and data science, arises naturally when deriving the dual to the problem of semi-algebraic D-optimal experimental design in…

Optimization and Control · Mathematics 2020-12-09 Yohann de Castro , Fabrice Gamboa , Didier Henrion , Jean Lasserre

In an order-of-addition experiment, each treatment is a permutation of m components. It is often unaffordable to test all the m! treatments, and the design problem arises. We consider a model that incorporates the order of each pair of…

Statistics Theory · Mathematics 2018-05-15 Jiayu Peng , Rahul Mukerjee , Dennis K. J. Lin

We present a unified deterministic approach for experimental design problems using the method of interlacing polynomials. Our framework recovers the best-known approximation guarantees for the well-studied D/A/E-design problems with simple…

Data Structures and Algorithms · Computer Science 2024-10-16 Lap Chi Lau , Robert Wang , Hong Zhou

This paper reviews the design of experiments for generalised linear models, including optimal design, Bayesian design and designs for models with random effects.

Methodology · Statistics 2015-10-20 Anthony C. Atkinson , David C. Woods

We consider experiments for comparing treatments using units that are ordered linearly over time or space within blocks. In addition to the block effect, we assume that a trend effect influences the response. The latter is modeled as a…

Statistics Theory · Mathematics 2008-12-18 Dibyen Majumdar , John Stufken

The purpose of this paper is to study optimality of circular neighbor-balanced block designs when neighbor effects are present in the model. In the literature many optimality results are established for direct effects and neighbor effects…

Statistics Theory · Mathematics 2007-06-13 R. A. Bailey , P. Druilhet

This paper introduces a framework to systematically optimize the control and design of an electric vehicle transmission, connecting powertrain sizing studies to detailed gearbox design methods. To this end, we first create analytical models…

Systems and Control · Electrical Eng. & Systems 2022-10-31 Olaf Borsboom , Thijs de Mooy , Mauro Salazar , Theo Hofman

In this paper we extend the results of Radloff and Schwabe (2018), which could be applied for example to Poisson regression, negative binomial regression and proportional hazard models with censoring, to a wider class of non-linear multiple…

Methodology · Statistics 2021-04-07 Martin Radloff , Rainer Schwabe

In this paper some new properties and computational tools for finding KL-optimum designs are provided. KL-optimality is a general criterion useful to select the best experimental conditions to discriminate between statistical models. A…

Methodology · Statistics 2018-01-04 Giacomo Aletti , Caterina May , Chiara Tommasi

In this work we build optimal experimental designs for precise estimation of the functional coefficient of a function-on-function linear regression model where both the response and the factors are continuous functions of time. After…

Methodology · Statistics 2024-12-20 Caterina May , Theodoros Ladas , Davide Pigoli , Kalliopi Mylona

We consider the utilization of a computational model to guide the optimal acquisition of experimental data to inform the stochastic description of model input parameters. Our formulation is based on the recently developed consistent…

Computation · Statistics 2021-05-04 Scott N. Walsh , Tim M. Wildey , John D. Jakeman

We clarify the mathematical structure underlying unitary $t$-designs. These are sets of unitary matrices, evenly distributed in the sense that the average of any $t$-th order polynomial over the design equals the average over the entire…

Quantum Physics · Physics 2009-11-13 D. Gross , K. Audenaert , J. Eisert

Classical designs of randomized experiments, going back to Fisher and Neyman in the 1930s still dominate practice even in online experimentation. However, such designs are of limited value for answering standard questions in settings,…

This short paper is concerned with the use of spherical t-designs as optimal designs for the spherical harmonic regression model in three dimensions over a range of specified criteria. The nature of the designs is explored and their…

Applications · Statistics 2024-11-21 Linda M. Haines

In paired comparison experiments respondents usually evaluate pairs of competing options. For this situation we introduce an appropriate model and derive optimal designs in the presence of second-order interactions when all attributes are…

Methodology · Statistics 2019-01-24 Eric Nyarko , Rainer Schwabe