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The major resolution-limiting factor in cryoelectron microscopy of unstained biological specimens is radiation damage by the very electrons that are used to probe the specimen structure. To address this problem, an electron microscopy…

Quantum Physics · Physics 2015-06-18 Hiroshi Okamoto

We study the entanglement creation between two flux qubits interacting with electromagnetic field modes. No direct interaction between the qubits exists. Entanglement is reached using entanglement swapping method by an interference…

Quantum Physics · Physics 2015-05-13 M. Kurpas , E. Zipper

Entanglement--one of the most delicate phenomena in nature--is an essential resource for quantum information applications. Large entangled cluster states have been predicted to enable universal quantum computation, with the required single-…

We show that quantum computational imaging is advantageous in the setting of low-dose electron microscopy of beam-sensitive specimens. Two qudits placed near the electron beam enable full transfer of quantum information between the electron…

Quantum Physics · Physics 2026-04-14 Hiroshi Okamoto

One of the astounding consequences of quantum mechanics is that it allows the detection of a target using an incident probe, with only a low probability of interaction of the probe and the target. This 'quantum weirdness' could be applied…

In this paper we discuss design concepts for increasing the spatial resolution, improving the sensitivity, and reducing the invasiveness in scanning Superconducting Quantum Interference Device (SQUID) microscope sensors with integrated flux…

Superconductivity · Physics 2010-02-09 Nicholas C. Koshnick , John R. Kirtley , Kathryn A. Moler

We propose a scheme for controlling a radio-frequency mechanical resonator at the quantum level using a superconducting qubit. The mechanical part of the circuit consists of a suspended micrometer-long beam that is embedded in the loop of a…

Quantum Physics · Physics 2020-06-16 Marios Kounalakis , Yaroslav M. Blanter , Gary A. Steele

Rapid evolutions of microscopic fields govern the majority of elementary excitations in condensed matter and drive microelectronic currents at increasing frequencies. Beyond nominal "radio frequencies", however, access to local electric…

We report development and microwave characterization of rf SQUID (Superconducting QUantum Interference Device) qubits, consisting of an aluminium-based Josephson junction embedded in a superconducting loop patterned from a thin film of TiN…

Mesoscale and Nanoscale Physics · Physics 2017-09-29 J. T. Peltonen , P. C. J. J. Coumou , Z. H. Peng , T. M. Klapwijk , J. S. Tsai , O. V. Astafiev

We propose a simple design of a quantum electron microscope that ``queries'' a beam-sensitive phase object, such as a biological specimen, as part of quantum computation. Lower quantum query complexity, not the time complexity, of a quantum…

Quantum Physics · Physics 2026-04-15 Hiroshi Okamoto

Feynman once asked physicists to build better electron microscopes to be able to watch biology at work. While electron microscopes can now provide atomic resolution, electron beam induced specimen damage precludes high resolution imaging of…

Instrumentation and Detectors · Physics 2016-12-16 Thomas Juffmann , Stewart A. Koppell , Brannon B. Klopfer , Colin Ophus , Robert Glaeser , Mark A. Kasevich

Quantum metrology experiments in atomic physics and quantum optics have demonstrated measurement accuracy beyond the shot-noise limit via multi-particle entanglement. At the same time, electron microscopy, an essential tool for…

Quantum physics has brought enhanced capability in various sensing applications. Despite challenges from noise and loss in the radio-frequency (RF) domain, [Phys. Rev. Lett. 124, 150502 (2020)] demonstrates a route for enhanced RF-receiver…

Quantum Physics · Physics 2025-03-06 Haowei Shi , Christopher M. Jones , Mengjie Yu , Zheshen Zhang , Quntao Zhuang

We use a scanning superconducting quantum interference device (SQUID) to image the magnetic flux produced by a superconducting device designed for quantum computing. The nanometer-scale SQUID-on-tip probe reveals the flow of superconducting…

Superconductivity · Physics 2022-09-16 E. Marchiori , L. Ceccarelli , N. Rossi , G. Romagnoli , J. Herrmann , J. -C. Besse , S. Krinner , A. Wallraff , M. Poggio

A superconducting flux qubit is inductively coupled to a Superconducting QUantum Interference Device (SQUID) magnetometer, capacitively shunted to form a 1.294-GHz resonator. The qubit-state-dependent resonator frequency is weakly probed…

Superconductivity · Physics 2012-03-07 J. E. Johnson , E. M. Hoskinson , C. Macklin , D. H. Slichter , I. Siddiqi , John Clarke

We propose a quantum-assisted reconstruction framework for high-resolution tomographic imaging that significantly reduces both qubit requirements and radiation exposure. Conventional quantum reconstruction methods require solving QUBO…

Quantum Physics · Physics 2025-04-30 Hyunju Lee , Kyungtaek Jun

The study of dynamic systems at the nanometer scale can benefit from the loss and background resilience offered by quantum two-photon interference. However, fast measurements with the required resolution are difficult to realize. As a…

Quantum Physics · Physics 2025-12-08 Colin P. Lualdi , Joshua Rapp , Spencer J. Johnson , Michael Vayninger , Paul G. Kwiat

Entanglement detection is a fundamental task in quantum information science, serving as a cornerstone for quantum benchmarking and foundational studies. With an increasing qubit number that can be effectively controlled, there is a pressing…

We demonstrate a new method for measuring radio frequency (RF) electric fields based on quantum interference in an atom. Using a bright resonance prepared within an electromagnetically induced transparency window we are able to achieve a…

Atomic Physics · Physics 2012-05-22 J. Sedlacek , A. Schwettmann , H. Kübler , R. Löw , T. Pfau , J. P. Shaffer

We show that radiation damage to unstained biological specimens is not an intractable problem in electron microscopy. When a structural hypothesis of a specimen is available, quantum mechanical principles allow us to verify the hypothesis…

Quantum Physics · Physics 2015-07-01 Hiroshi Okamoto , Tatiana Latychevskaia , Hans-Werner Fink
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