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During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process. The continuous positional information…

Molecular Networks · Quantitative Biology 2017-02-08 Ruben Perez-Carrasco , Pilar Guerrero , James Briscoe , Karen Page

Humans and other organisms make decisions choosing between different options, with the aim to maximize the reward and minimize the cost. The main theoretical framework for modeling the decision-making process has been based on the highly…

Neurons and Cognition · Quantitative Biology 2024-11-19 Olga Tapinova , Tal Finkelman , Tamar Reitich-Stolero , Rony Paz , Assaf Tal , Nir S. Gov

In Valence Change Memory (VCM) cells, the conductance of an insulating switching layer is reversibly modulated by creating and redistributing point defects under an external field. Accurate simulations of the switching dynamics of these…

Disordered Systems and Neural Networks · Physics 2023-01-02 Manasa Kaniselvan , Mathieu Luisier , Marko Mladenović

The electronic conduction of a novel, three-terminal molecular architecture, analogous to a heterojunction bipolar transistor is studied. In this architecture, two diode arms consisting of donor-acceptor molecular wires fuse through a ring,…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Haiying He , Ravindra Pandey , Shashi P. Karna

Travelling waves of neural firing activity are observed in brain tissue as a part of various sensory, motor and cognitive processes. They represent an object of major interest in the study of excitable networks, with analysis conducted in…

Neurons and Cognition · Quantitative Biology 2025-11-10 Henry D. J. Kerr , Peter Ashwin , Kyle C. A. Wedgwood

In this paper, we study pairs of oscillators that are indirectly coupled via active (excitable) cells. We introduce a scalar phase model for coupled oscillators and excitable cells. We first show that one excitable and one oscillatory cell…

Dynamical Systems · Mathematics 2019-06-05 Derek Orr , Bard Ermentrout

We have varied the disorder in a two-dimensional electron system in silicon by applying substrate bias. When the disorder becomes sufficiently low, we observe the emergence of the metallic phase, and find evidence for a metal-insulator…

Strongly Correlated Electrons · Physics 2009-10-30 Dragana Popovic , A. B. Fowler , S. Washburn

Cell crawling on flat substrates is based on intracellular flows of the actin cytoskeleton that are driven by both actin polymerization at the front and myosin contractility at the back. The new experimental tool of optogenetics makes it…

Subcellular Processes · Quantitative Biology 2023-07-04 Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Mechanistic interpretability has transformed the analysis of transformer circuits by decomposing model behavior into competing algorithms, identifying phase transitions during training, and deriving closed-form predictions for when and why…

Machine Learning · Computer Science 2026-03-19 Alma Lago

Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…

Neurons and Cognition · Quantitative Biology 2015-07-23 Pengsheng Zheng

This paper presents a methodology of controlling the resonance energy exchange in mechanical system consisting of two weakly coupled magnetic pendulums interacting with the magnetic field generated by coils placed underneath. It is shown…

Systems and Control · Electrical Eng. & Systems 2023-04-20 Valery N. Pilipchuk , Krystian Polczyński , Maksymilian Bednarek , Jan Awrejcewicz

We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that…

Neurons and Cognition · Quantitative Biology 2015-06-11 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre

We analyse biased ensembles of trajectories for the random-field Ising model on a fully-connected lattice, which is described exactly by mean-field theory. By coupling the activity of the system to a dynamical biasing field, we find a range…

Statistical Mechanics · Physics 2021-10-27 Jules Guioth , Robert L. Jack

We present an approach for constructing dynamic models for the simulation of gene regulatory networks from simple computational elements. Each element is called a ``gene gate'' and defines an input/output-relationship corresponding to the…

Molecular Networks · Quantitative Biology 2007-10-09 R. Blossey , L. Cardelli , A. Phillips

In our previous work, we proposed a novel neuron model based on symmetric differential equations and demonstrated its potential as an efficient signal propagator. Building upon that foundation, the present study delves deeper into the…

Neural and Evolutionary Computing · Computer Science 2025-08-01 Kun Jiang

We consider a general class of translation-invariant systems with a specific category of output nonlinearities motivated by biological sensing. We show that no dynamic output feedback can stabilize this class of systems to an isolated…

Systems and Control · Electrical Eng. & Systems 2025-02-21 Debojyoti Biswas , Eduardo D. Sontag , Noah J. Cowan

The present habilitation thesis in theoretical biological physics addresses two central dynamical processes in cells and organisms: (i) active motility and motility control and (ii) self-organized pattern formation. The unifying theme is…

Cell Behavior · Quantitative Biology 2018-03-21 Benjamin M. Friedrich

Power transistors such as IGBTs and MOSFETs are a source of electromagnetic interference (EMI) during switching due to rapid voltage/current variations. Increasing the switching time can reduce the generation of EMI but increases losses.…

Systems and Control · Electrical Eng. & Systems 2023-07-28 Daniel Sting Martinez-Padron , Nicolas Patin , Eric Monmasson

Oscillatory activity is ubiquitous in natural and engineered network systems. The interaction scheme underlying interdependent oscillatory components governs the emergence of network-wide patterns of synchrony that regulate and enable…

Adaptation and Self-Organizing Systems · Physics 2022-08-12 Tommaso Menara , Giacomo Baggio , Danielle S. Bassett , Fabio Pasqualetti

The possibility of electron beam guiding is theoretically explored on the surface of a topological insulator through the proximity interaction with a magnetic material. The electronic band modification induced by the exchange coupling at…

Mesoscale and Nanoscale Physics · Physics 2015-06-17 Xiaodong Li , Ki Wook Kim
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