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I review the advancements of atomic scale nanoelectronics towards quantum neuromorphics. First, I summarize the key properties of elementary combinations of few neurons, namely long-- and short--term plasticity, spike-timing dependent…

Emerging Technologies · Computer Science 2016-09-21 Enrico Prati

Neuromorphic computing aims to reproduce the energy efficiency and adaptability of biological intelligence in hardware. Superconducting devices are an attractive platform due to their ultra-low dissipation and fast switching dynamics. Here…

Superconductivity · Physics 2026-02-17 Khalil Harrabi , Leonardo Cadorim , Milorad Milosevic

Artificial Neural Networks (ANNs) are one of the most widely employed forms of bio-inspired computation. However the current trend is for ANNs to be structurally homogeneous. Furthermore, this structural homogeneity requires the application…

Neural and Evolutionary Computing · Computer Science 2024-03-26 Andrew Walter , Shimeng Wu , Andy M. Tyrrell , Liam McDaid , Malachy McElholm , Nidhin Thandassery Sumithran , Jim Harkin , Martin A. Trefzer

The memory demands of large-scale deep neural networks (DNNs) require synaptic weight values to be stored and updated in off-chip memory like dynamic random-access memory, which reduces energy efficiency and increases training time.…

Applied Physics · Physics 2025-10-08 Abhishek Kumar , Peter D. Hodgson , Manus Hayne , Avirup Dasgupta

This paper presents verification and implementation methods that have been developed for the design of the BrainScaleS-2 65nm ASICs. The 2nd generation BrainScaleS chips are mixed-signal devices with tight coupling between full-custom…

Hardware Architecture · Computer Science 2020-03-26 Andreas Grübl , Sebastian Billaudelle , Benjamin Cramer , Vitali Karasenko , Johannes Schemmel

A striking difference between brain-inspired neuromorphic processors and current von Neumann processors architectures is the way in which memory and processing is organized. As Information and Communication Technologies continue to address…

Neural and Evolutionary Computing · Computer Science 2017-11-08 Giacomo Indiveri , Shih-Chii Liu

Arbor is a software library designed for efficient simulation of large-scale networks of biological neurons with detailed morphological structures. It combines customizable neuronal and synaptic mechanisms with high-performance computing,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-16 Jannik Luboeinski , Sebastian Schmitt , Shirin Shafiee , Thorsten Hater , Fabian Bösch , Christian Tetzlaff

Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…

Neurons and Cognition · Quantitative Biology 2015-05-05 Maurizio De Pittà , Nicolas Brunel , Andrea Volterra

Information in neural networks is represented as weighted connections, or synapses, between neurons. This poses a problem as the primary computational bottleneck for neural networks is the vector-matrix multiply when inputs are multiplied…

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Neuromorphic engineering makes use of mixed-signal analog and digital circuits to directly emulate the computational principles of biological brains. Such electronic systems offer a high degree of adaptability, robustness, and energy…

Systems and Control · Electrical Eng. & Systems 2026-04-09 Loris Mendolia , Chenxi Wen , Elisabetta Chicca , Giacomo Indiveri , Rodolphe Sepulchre , Jean-Michel Redouté , Alessio Franci

Neuromorphic devices have gained significant attention as potential building blocks for the next generation of computing technologies owing to their ability to emulate the functionalities of biological nervous systems. The essential…

Optical communication achieves high fanout and short delay advantageous for information integration in neural systems. Superconducting detectors enable signaling with single photons for maximal energy efficiency. We present designs of…

Neural and Evolutionary Computing · Computer Science 2018-11-14 Jeffrey M. Shainline , Sonia M. Buckley , Adam N. McCaughan , Jeff Chiles , Richard P. Mirin , Sae Woo Nam

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

This paper describes how realistic neuromorphic networks can have their connectivity fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the two-dimensional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Luciano da Fontoura Costa , Marconi Soares Barbosa

Traditional computation based on von Neumann architecture is limited by the time and energy consumption due to data transfer between the storage and the processing units. The von Neumann architecture is also inefficient in solving…

Emerging Technologies · Computer Science 2023-01-04 Dheemahi Rao , Bivas Saha

The approximation capability of ANNs and their RNN instantiations, is strongly correlated with the number of parameters packed into these networks. However, the complexity barrier for human understanding, is arguably related to the number…

Neural and Evolutionary Computing · Computer Science 2023-03-10 Julian Lemmel , Radu Grosu

Our current understanding of neuroplasticity paints a picture of a complex interconnected system of dependent processes which shape cortical structure so as to produce an efficient information processing system. Indeed, the cooperation of…

Neurons and Cognition · Quantitative Biology 2018-04-03 Zoe Tosi , John Beggs

Neuropeptides, members of a large and evolutionarily ancient family of proteinaceous cell-cell signaling molecules, are widely recognized as extremely potent regulators of brain function and behavior. At the cellular level, neuropeptides…

Neurons and Cognition · Quantitative Biology 2020-04-20 Stephen J. Smith , Michael Hawrylycz , Jean Rossier , Uygar Sümbül

Learning in living organisms is typically associated with networks of neurons. The use of large numbers of adjustable units has also been a crucial factor in the continued success of artificial neural networks. In light of the complexity of…

Neurons and Cognition · Quantitative Biology 2024-05-10 Matthew Smart , Stanislav Y. Shvartsman , Martin Mönnigmann
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