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Related papers: SMaSH: A Benchmarking Toolkit for Human Genome Var…

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Semantic hashing represents documents as compact binary vectors (hash codes) and allows both efficient and effective similarity search in large-scale information retrieval. The state of the art has primarily focused on learning hash codes…

Information Retrieval · Computer Science 2021-03-29 Christian Hansen , Casper Hansen , Jakob Grue Simonsen , Stephen Alstrup , Christina Lioma

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the…

Genomics · Quantitative Biology 2024-06-18 Teddy Lazebnik , Liron Simon-Keren

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Clinical adoption of human genome sequencing requires methods with known accuracy of genotype calls at millions or billions of positions across a genome. Previous work showing discordance amongst sequencing methods and algorithms has made…

Genomics · Quantitative Biology 2014-02-18 Justin M. Zook , Brad Chapman , Jason Wang , David Mittelman , Oliver Hofmann , Winston Hide , Marc Salit

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

Cell clustering is crucial for uncovering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq) data by identifying cell types and marker genes. Despite its importance, benchmarks for scRNA-seq clustering methods remain…

Genomics · Quantitative Biology 2025-12-03 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Jiajia Wang , Ran Zhang , Pengfei Wang , Yuanchun Zhou

Recent advances in generative models have led to their application in password guessing, with the aim of replicating the complexity, structure, and patterns of human-created passwords. Despite their potential, inconsistencies and inadequate…

Cryptography and Security · Computer Science 2025-10-20 William Corrias , Fabio De Gaspari , Dorjan Hitaj , Luigi V. Mancini

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

Schema Matching is a method of finding attributes that are either similar to each other linguistically or represent the same information. In this project, we take a hybrid approach at solving this problem by making use of both the provided…

Databases · Computer Science 2020-04-22 Tanvi Sahay , Ankita Mehta , Shruti Jadon

Semantic hashing has become a powerful paradigm for fast similarity search in many information retrieval systems. While fairly successful, previous techniques generally require two-stage training, and the binary constraints are handled…

Computation and Language · Computer Science 2018-05-16 Dinghan Shen , Qinliang Su , Paidamoyo Chapfuwa , Wenlin Wang , Guoyin Wang , Lawrence Carin , Ricardo Henao

Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are starting to be used as markers to improve prognosis or…

Genomics · Quantitative Biology 2008-01-22 Franck Rapaport , Emmanuel Barillot , Jean-Philippe Vert

Background: Advances in high throughput sequencing technologies provide a huge number of genomes to be analyzed. Thus, computational methods play a crucial role in analyzing and extracting knowledge from the data generated. Investigating…

In this paper we provide a broad benchmarking of recent genetic programming approaches to symbolic regression in the context of state of the art machine learning approaches. We use a set of nearly 100 regression benchmark problems culled…

Neural and Evolutionary Computing · Computer Science 2018-06-08 Patryk Orzechowski , William La Cava , Jason H. Moore

The use of deep learning models in computational biology has increased massively in recent years, and it is expected to continue with the current advances in the fields such as Natural Language Processing. These models, although able to…

Quantum information processing offers promising advances for a wide range of fields and applications, provided that we can efficiently assess the performance of the control applied in candidate systems. That is, we must be able to determine…

Quantum Physics · Physics 2015-01-26 Christopher Granade , Christopher Ferrie , D. G. Cory

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

As quantum technology matures, the efficient benchmarking of quantum devices remains a key challenge. Although sample-efficient, information-theoretic benchmarking techniques have recently been proposed, there is still a gap in adapting…

Quantum Physics · Physics 2025-10-22 Ana Silva , Eliska Greplova

The detection of rare variants is important for understanding the genetic heterogeneity in mixed samples. Recently, next-generation sequencing (NGS) technologies have enabled the identification of single nucleotide variants (SNVs) in mixed…

Genomics · Quantitative Biology 2016-04-25 Fan Zhang , Patrick Flaherty

Nanopore sequencing technologies continue to advance rapidly, offering critical benefits such as real-time analysis, the ability to sequence extremely long DNA fragments (up to millions of bases in a single read), and the option to…

Genomics · Quantitative Biology 2025-10-07 Furkan Eris , Ulysse McConnell , Can Firtina , Onur Mutlu

Variant and gene interpretation are fundamental to personalized medicine and translational biomedicine. However, traditional approaches are manual and labor-intensive. Generative language models (LMs) can facilitate this process,…

Artificial Intelligence · Computer Science 2025-10-15 Owen Queen , Harrison G. Zhang , James Zou