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In the presence of modeling errors, the mainstream Bayesian methods seldom give a realistic account of uncertainties as they commonly underestimate the inherent variability of parameters. This problem is not due to any misconception in the…

Applications · Statistics 2020-05-19 Omid Sedehi , Costas Papadimitriou , Lambros S. Katafygiotis

Network growth processes can be understood as generative models of the structure and history of complex networks. This point of view naturally leads to the problem of network archaeology: reconstructing all the past states of a network from…

This paper analyzes hierarchical Bayesian inverse problems using techniques from high-dimensional statistics. Our analysis leverages a property of hierarchical Bayesian regularizers that we call approximate decomposability to obtain…

Statistics Theory · Mathematics 2024-01-09 Daniel Sanz-Alonso , Nathan Waniorek

Comparing paleoclimate time series is complicated by a variety of typical features, including irregular sampling, age model uncertainty (e.g., errors due to interpolation between radiocarbon sampling points) and time uncertainty…

Applications · Statistics 2019-03-29 Jasper G. Franke , Reik V. Donner

We develop and apply a learning framework for parameter estimation in initial value problems that are assessed only indirectly via aggregate data such as sample means and/or standard deviations. Our comprehensive framework follows Bayesian…

Quantitative Methods · Quantitative Biology 2025-06-27 Stephen McCoy , Daniel McBride , D. Katie McCullough , Benjamin C. Calfee , Erik Zinser , David Talmy , Ioannis Sgouralis

In this work, we propose a Bayesian thinning algorithm for recovering weighted point source functions in the heat equation from boundary flux observations. The major challenge in the classical Bayesian framework lies in constructing…

Computation · Statistics 2025-09-19 Zhiliang Deng , Chen Li , Xiaomei Yang

While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and their applicability over macroscopic time scales of physical…

Machine Learning · Statistics 2016-09-08 P. S. Koutsourelakis , Elias Bilionis

Multilevel models (MLMs) are a central building block of the Bayesian workflow. They enable joint, interpretable modeling of data across hierarchical levels and provide a fully probabilistic quantification of uncertainty. Despite their…

Multiscale modeling is a systematic approach to describe the behavior of complex systems by coupling models from different scales. The approach has been demonstrated to be very effective in areas of science as diverse as materials science,…

Computational Physics · Physics 2020-01-08 Ting Wang , Kenneth W. Leiter , Petr Plechac , Jaroslaw Knap

Comparative and evolutive ecologists are interested in the distribution of quantitative traits among related species. The classical framework for these distributions consists of a random process running along the branches of a phylogenetic…

Applications · Statistics 2017-08-24 Paul Bastide , Mahendra Mariadassou , Stéphane Robin

Introduction : Mass spectrometry approaches are very attractive to detect protein panels in a sensitive and high speed way. MS can be coupled to many proteomic separation techniques. However, controlling technological variability on these…

Genomics · Quantitative Biology 2012-02-23 Pierre Grangeat , Pascal Szacherski , Laurent Gerfault , Jean-François Giovannelli

Bayesian paradigm takes advantage of well fitting complicated survival models and feasible computing in survival analysis owing to the superiority in tackling the complex censoring scheme, compared with the frequentist paradigm. In this…

Methodology · Statistics 2021-09-10 Chong Zhong , Zhihua Ma , Junshan Shen , Catherine Liu

A frequent challenge encountered with compositional ecological data is how to interpret and model data with a high proportion of zeros and $N$'s. Such data frequently occur in ecological applications where counts of species are collected…

Methodology · Statistics 2025-08-04 James Sweeney , John Haslett , Dipankar Bandyopadhyay , Michael Fop , Andrew C. Parnell

A fully Bayesian approach is proposed for ultrahigh-dimensional nonparametric additive models in which the number of additive components may be larger than the sample size, though ideally the true model is believed to include only a small…

Methodology · Statistics 2013-09-24 Zuofeng Shang , Ping Li

Phylodynamics focuses on the problem of reconstructing past population size dynamics from current genetic samples taken from the population of interest. This technique has been extensively used in many areas of biology, but is particularly…

Computation · Statistics 2015-07-23 Shiwei Lan , Julia A. Palacios , Michael Karcher , Vladimir N. Minin , Babak Shahbaba

Multilevel compositional data are data that are repeatedly measured or clustered within groups and are non-negative and sum to a constant value. These data arise in various settings, such as intensive, longitudinal studies using ecological…

Methodology · Statistics 2025-02-21 Flora Le , Tyman E. Stanford , Dorothea Dumuid , Joshua F. Wiley

Phylogenetics, the inference of evolutionary trees from molecular sequence data such as DNA, is an enterprise that yields valuable evolutionary understanding of many biological systems. Bayesian phylogenetic algorithms, which approximate a…

Populations and Evolution · Quantitative Biology 2016-10-27 Vu Dinh , Aaron E. Darling , Frederick A. Matsen

Molecular phylogenetic and phylogeographic reconstructions generally assume time-homogeneous substitution processes. Motivated by computational convenience, this assumption sacrifices biological realism and offers little opportunity to…

Populations and Evolution · Quantitative Biology 2013-09-13 Filip Bielejec , Philippe Lemey , Guy Baele , Andrew Rambaut , Marc A Suchard

Scientific studies in many areas of biology routinely employ evolutionary analyses based on the probabilistic inference of phylogenetic trees from molecular sequence data. Evolutionary processes that act at the molecular level are highly…

Populations and Evolution · Quantitative Biology 2024-12-10 Mandev S. Gill , Guy Baele , Marc A. Suchard , Philippe Lemey

A model-independent or non-parametric approach for modeling a database has been widely used in cosmology. In these scenarios, the data has been used directly to reconstruct an underlying function. In this work, we introduce a novel…

Cosmology and Nongalactic Astrophysics · Physics 2023-01-19 Ahmad Mehrabi