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The Jansen-Rit model of a cortical column in the cerebral cortex is widely used to simulate spontaneous brain activity (EEG) and event-related potentials. It couples a pyramidal cell population with two interneuron populations, of which one…

Dynamical Systems · Mathematics 2025-02-11 Huda Mahdi , Jan Sieber , Krasimira Tsaneva-Atanasova

In this paper we study the emergence of homeostasis in a two-layer system of the Game of Life, in which the Game of Life in the first layer couples with another system of cellular automata in the second layer. Homeostasis is defined here as…

Neural and Evolutionary Computing · Computer Science 2024-05-10 Keisuke Suzuki , Takashi Ikegami

Coupled biological oscillators can tick with the same period. How this collective period is established is a key question in understanding biological clocks. We explore this question in the segmentation clock, a population of coupled…

Tissues and Organs · Quantitative Biology 2010-09-03 Leah Herrgen , Saul Ares , Luis G. Morelli , Christian Schroeter , Frank Julicher , Andrew C. Oates

The equilibration of sinusoidally modulated distribution of the kinetic temperature is analyzed in the $\beta$-Fermi-Pasta-Ulam-Tsingou chain with different degrees of nonlinearity and for different wavelengths of temperature modulation.…

A variety of nonlinear models of biological systems generate complex chaotic behaviors that contrast with biological homeostasis, the observation that many biological systems prove remarkably robust in the face of changing external or…

Chaotic Dynamics · Physics 2023-07-07 Jonathan Jaquette , Sonal Kedia , Evelyn Sander , Jonathan D. Touboul

A minimalistic model of the half-center oscillator is proposed. Within it, we consider dynamics of two excitable neurons interacting by means of the excitatory coupling. In the parameter space of the model, we identify the regions of…

Dynamical Systems · Mathematics 2021-03-02 A. G. Korotkov , T. A. Levanova , M. A. Zaks , G. V. Osipov

Synchronization is studied in a spatially-distributed network of weekly-coupled, excitatory neurons of Hodgkin-Huxley type. All neurons are coupled to each other synaptically with a fixed time delay and a coupling strength inversely…

Soft Condensed Matter · Physics 2007-05-23 Yuqing Wang , Z. D. Wang , Y. -X. Li , X. Pei

We consider a single theta neuron with delayed self-feedback in the form of a Dirac delta function in time. Because the dynamics of a theta neuron on its own can be solved explicitly -- it is either excitable or shows self-pulsations -- we…

Dynamical Systems · Mathematics 2023-01-11 Carlo R. Laing , Bernd Krauskopf

Unlike isolated beta-cells, which usually produce continuous spikes or fast and irregular bursts, electrically coupled beta-cells are apt to exhibit robust bursting action potentials. We consider the noise induced by thermal fluctuations as…

Cell Behavior · Quantitative Biology 2007-05-23 J. Jo , H. Kang , M. Y. Choi , D. S. Koh

We analyze the collective behavior of a lattice model of pulse-coupled oscillators. By means of computer simulations we find the relation between the intrinsic dynamics of each member of the population and their mutual interaction that…

Condensed Matter · Physics 2009-10-28 Alvaro Corral , Conrad J. Perez , Albert Diaz-Guilera , Alex Arenas

In this article we study the behavior of globally coupled assemblies of a large number of Integrate and Fire oscillators with excitatory pulse-like interactions. On some simple models we show that the additive effects of pulses on the state…

Condensed Matter · Physics 2009-10-28 Samuele Bottani

To understand the sophisticated control mechanisms of the human's endocrine system is a challenging task that is a crucial step towards precise medical treatment of many disfunctions and diseases. Although mathematical models describing the…

Systems and Control · Computer Science 2019-09-20 Hadi Taghvafard , Anton V. Proskurnikov , Ming Cao

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…

Data Analysis, Statistics and Probability · Physics 2009-11-13 Ronny Bartsch , Jan W. Kantelhardt , Thomas Penzel , Shlomo Havlin

We consider a pair of identical theta neurons in the excitable regime, each coupled to the other via a delayed Dirac delta function with the same delay. This simple network can support different periodic solutions, and we concentrate on two…

Pattern Formation and Solitons · Physics 2024-12-11 Carlo R. Laing , Bernd Krauskopf

The organization of live cells to tissues is associated with the mechanical interaction between cells, which is mediated through their elastic environment. We model cells as spherical active force dipoles surrounded by an infinite elastic…

Biological Physics · Physics 2017-06-08 Roman Golkov , Yair Shokef

The density of synaptic receptors in front of presynaptic release sites is stabilized in the presence of scaffold proteins, but the receptors and scaffold molecules have local exchanges with characteristic times shorter than that of the…

Biological Physics · Physics 2009-11-13 Ken Sekimoto , Antoine Triller

We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled…

Soft Condensed Matter · Physics 2015-06-23 M. Leoni , P. Sens

Understanding complex systems which exhibit desynchronization as an emergent property should have important implications, particularly in treating neurological disorders and designing efficient communication networks. Here were demonstrate…

Mathematical Physics · Physics 2012-11-06 J. Borresen , D. Broomhead

We investigate the combined effects of distributed delay and the balance between excitatory and inhibitory nodes on the stability of synchronous oscillations in a network of coupled Stuart--Landau oscillators. To this end a network model is…

Adaptation and Self-Organizing Systems · Physics 2014-09-16 Carolin Wille , Judith Lehnert , Eckehard Schöll