Related papers: A feasible roadmap for unsupervised deconvolution …
Bulk gene expression experiments relied on aggregations of thousands of cells to measure the average expression in an organism. Advances in microfluidic and droplet sequencing now permit expression profiling in single cells. This study of…
We present a method for fine-grained face manipulation. Given a face image with an arbitrary expression, our method can synthesize another arbitrary expression by the same person. This is achieved by first fitting a 3D face model and then…
Many high-dimensional data sets suffer from hidden confounding which affects both the predictors and the response of interest. In such situations, standard regression methods or algorithms lead to biased estimates. This paper substantially…
Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in…
Endmember (EM) spectral variability can greatly impact the performance of standard hyperspectral image analysis algorithms. Extended parametric models have been successfully applied to account for the EM spectral variability. However, these…
It has previously been hypothesized, and supported with some experimental evidence, that deeper representations, when well trained, tend to do a better job at disentangling the underlying factors of variation. We study the following related…
This work studies the problem of estimating a two-dimensional superposition of point sources or spikes from samples of their convolution with a Gaussian kernel. Our results show that minimizing a continuous counterpart of the $\ell_1$ norm…
We propose an approach to learn image representations that consist of disentangled factors of variation without exploiting any manual labeling or data domain knowledge. A factor of variation corresponds to an image attribute that can be…
Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult. Currently, the…
Generating faithful visualizations of human faces requires capturing both coarse and fine-level details of the face geometry and appearance. Existing methods are either data-driven, requiring an extensive corpus of data not publicly…
We present a method for feature interpretation that makes use of recent advances in autoregressive density estimation models to invert model representations. We train generative inversion models to express a distribution over input features…
We consider the problem of multivariate density deconvolution where the distribution of a random vector needs to be estimated from replicates contaminated with conditionally heteroscedastic measurement errors. We propose a conceptually…
Hyperspectral unmixing, the process of estimating a common set of spectral bases and their corresponding composite percentages at each pixel, is an important task for hyperspectral analysis, visualization and understanding. From an…
The reconstruction of phylogenetic trees from mixed populations has become important in the study of cancer evolution, as sequencing is often performed on bulk tumor tissue containing mixed populations of cells. Recent work has shown how to…
This paper addresses mesh restoration problems, i.e., denoising and completion, by learning self-similarity in an unsupervised manner. For this purpose, the proposed method, which we refer to as Deep Mesh Prior, uses a graph convolutional…
We consider the multichannel blind deconvolution problem where we observe the output of multiple channels that are all excited with the same unknown input. From these observations, we wish to estimate the impulse responses of each of the…
There have been a fairly of research interests in exploring the disentanglement of appearance and shape from human images. Most existing endeavours pursuit this goal by either using training images with annotations or regulating the…
In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal…
Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…
Lexical ambiguity makes it difficult to compute various useful statistics of a corpus. A given word form might represent any of several morphological feature bundles. One can, however, use unsupervised learning (as in EM) to fit a model…